This book features an in-depth examination of the ongoing problem of bovine mastitis and the potential solutions offered by polymer nanoparticles. With extensive research and analysis, the book delves into the causes and consequences of bovine mastitis, including the shift in the relevance of various infections and the increasing problem of antibiotic resistance. The authors explore the use of nanoparticles as a potential alternative to traditional antibiotics and the importance of tailoring their characteristics for specific uses. Detailed discussions of the pros and cons of different manufacturing procedures and characterizations of bovine mastitis, drug-resistant bacteria, and resistance development make this monograph an invaluable resource for researchers and experts in the field of veterinary medicine, and an excellent resource for those interested in investigating the viability of nano-materials as future antibiotic alternatives.

Worldwide, mastitis is still one of the most important diseases in the dairy sector. Being a multifactorial disease, caused by multiple pathogens, control remains a difficult issue. Mastitis not only affects the health of milk-producing animals, having consequences for the profitability of dairy farms, it also affects the animal welfare. Moreover, mastitis negatively influences the milk quality having consequences for the dairy processing industry. In other words: mastitis affects a large part of the dairy production chain. Due to ongoing scientific effort, insight in mastitis in the context of increasingly complex farming systems, is improving. This insight leads to better methods to control mastitis, either by prevention or by adequate measures (e.g. therapy) when a cow (or goat or sheep) gets mastitis. This book reflects the current knowledge from all over the world on mastitis as it was presented during the 4th IDF International Mastitis Conference, held in June 2005 in Maastricht, the Netherlands. The papers of the 115 oral presentations and the 13 keynote presentations are reflecting not only the current knowledge of mastitis control but are also giving ideas for future solutions for control measures.

Introducing Smart Nanocarrier for Effective Drug Delivery—a pioneering guide that delves into the realm of nanotechnology and its revolutionary impact on drug delivery systems. This comprehensive volume offers a deep understanding of smart nanocarriers' principles, design, and applications, setting it apart as a cutting-edge resource in the field. Nanotechnology has transformed drug delivery, enhanced therapeutic outcomes, and minimized side effects. This book provides a concise yet thorough overview of this dynamic landscape, elucidating key concepts and methodologies. It covers foundational principles and explores advanced strategies for targeted drug delivery, personalized medicine, and combination therapy. KEY FEATURES In-depth exploration of various types of nanocarriers, from liposomes to polymeric nanoparticles, highlighting their unique attributes. Detailed examination of smart stimuli-responsive nanocarriers that release drugs at precise locations and times. Comprehensive analysis of the latest advancements in nanomedicine, including nanodiagnostics and theranostics. Case studies illustrating real-world applications and success stories of nanocarrier-enhanced drug delivery. Smart Nanocarrier for Effective Drug Delivery is an invaluable resource for researchers, practitioners, and students in pharmaceutical sciences, nanotechnology, and drug delivery. It offers a roadmap to harnessing the potential of nanocarriers for enhancing therapeutic efficacy while minimizing adverse effects. This book equips readers with the knowledge to navigate the rapidly evolving landscape of smart nanocarrier technology, making it an essential addition to their professional toolkit.

The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy. Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.

Recognising the future leaders of Comparative and Clinical Medicine is fundamental to safeguarding tomorrow's driving force in innovation. This collection will showcase the high-quality work of internationally recognized researchers in the early stages of their careers. We aim to highlight research by leading scientists of the future across the entire breadth of Comparative and Clinical Medicine and present advances in theory, experiment, and methodology with applications to compelling problems.

Veterinary medicine is advancing at a very rapid pace, particularly given the breadth of the discipline. This book examines new developments covering a wide range of issues from health and welfare in livestock, pets, and wild animals to public health supervision and biomedical research. As well as containing reviews offering fresh insight into specific issues, this book includes a selection of scientific articles which help to chart the advance of this science. The book is divided into several sections. The opening chapters cover the veterinary profession and veterinary science in general, while later chapters look at specific aspects of applied veterinary medicine in pets and in livestock. Finally, research papers are grouped by specialisms with a view to exploring progress in areas such as organ transplantation, therapeutic use of natural substances, and the use of new diagnostic techniques for disease control. This book was produced during World Veterinary Year 2011, which marked the 250th anniversary of the veterinary profession. It provides a fittingly concise and enjoyable overview of the whole science of veterinary medicine.

This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

Antibiotics, the backbone of modern clinical-medicine, are facing serious challenges from emerging antimicrobial-resistance (AMR), a complicated phenomenon expanding in bacterial species, from nosocomial to community origins, where microbes are no longer sensitive to a range of commonly used antibiotics. AMR has exploded in recent years and is posing a serious threat to human health and survival. This necessitates novel and effective ways of diagnosis, drug-delivery, and treatment; nanotechnology and advanced nanomaterials are hailed as a potent solution in containing AMR.The main thrust of this volume is to explain the most current research on the central theme of potential use of nano-approaches for diagnosis, detection, drug-delivery and as antimicrobial agents against drug-resistant pathogenic microbes. This book provides an integrated blend of basic and advanced information for students, scholars, scientists and practitioners, interested or already engaged in research in these areas. We have brought together leading international authors to present and highlight various aspects of nanotechnology in combating AMR in WHO-prioritized microbes. Topics range from advances in nanomaterial synthesis, characterization, functionalization and improvisation, as well as applications in sensing, diagnosis of AMR, and their therapeutic and drug-delivery potential against MDR and XDR microbial phenotypes.

This cutting-edge reference book discusses the biomedical applications of nanomaterials. It covers different types of nanoparticles, such as polymeric nanoparticles, lipoidal nanoparticles, and metallic nanoparticles. It discusses the current trends and challenges in the development of safe biomedicines. The book reviews FDA-approved medicines, nanohybrid systems for early-stage diagnosis and treatment of diseases, advanced approaches of cost-effective bio-imaging, and theragnostics. It also covers the basic design and fundamental understanding of surface-engineered biomedicine. The book is meant for experts in the healthcare industry as well as post-graduates in biomedical engineering and nanotechnology.

This is the second edition of the book, containing 16 chapters which focus on prevention and control of mastitis as well as on the different factors that lead to mastitis resulting in poor milk quality. The book contains two appendices, the first contains a liner line chart and the second contains parlour audit. An index is also provided.