This issue of Neurosurgery Clinics, Guest Edited by Drs. Manish K. Aghi and Lewis S. Blevins, will focus on Pituitary Adenoma. Topics include, but are not limited to, Molecular biology of nonfunctional and functional pituitary adenomas, Intraoperative Fluorescent Visualization of pituitary adenomas, Intraoperative MRI for pituitary adenomas, Pituitary Apoplexy, Management of giant pituitary adenomas, Management of Pituitary Adenomas Invading the Cavernous Sinus, Management of Recurrent Pituitary Adenomas, Medical Management of Cushing’s Disease, Medical Management of Acromegaly, Surgery for Pediatric Pituitary Adenomas, Visual Outcomes after Pituitary Surgery, Endocrine Outcomes after Pituitary Surgery, Sodium perturbations after pituitary surgery, and Sinonasal Quality of Life After Pituitary Surgery.

This issue of the Neurosurgery Clinics of North America, Guest Edited by Drs. Manish Aghi and Lewis Blevins, is devoted to Management of Pituitary Tumors. Experts in the field have assembled to provide articles on Imaging of the pituitary and parasellar region; Management of Incidentally Found Nonfunctional Pituitary Tumors; Endoscopic Surgery for Pituitary Tumors; Prolactinomas – Medical versus Surgical Management; Neurosurgery for Cushing’s Disease; Postoperative radiotherapy and stereotactic radiosurgery for pituitary tumors; Management options for persistent postoperative acromegaly; Medical management of persistent and recurrent Cushing’s disease; Management of Large Aggressive Nonfunctional Pituitary Tumors – Experimental Medical Options when Surgery and Radiation Fail; Pituitary Carcinoma; Visual Outcomes after Surgery For Nonfunctional Adenomas Causing Visual Compromise; and Hypopituitarism and Central Diabetes Insipidus: Peri-Operative Diagnosis and Management.

This issue of Neurosurgery Clinics focus on Intraoperative Imaging. Article topics will include historical, current and future intraoperative imaging modality; iMRI suites: history, design, utility and cost-effectiveness; Stereotactic platforms for iMRI; iMRI for tumor: maximizing extent of resection of glioma; IMRI for tumor: combining iMRI with functional MRI; iMRI for tumor: pituitary adenoma; iMRI for tumor: MR thermometry; iMRI for tumor: LITT for spinal tumors; iMRI for functional/epilepsy neurosurgery: DBS placement; iMRI for functional/epilepsy neurosurgery: MR thermometry for mesial temporal epilepsy; iMRI for functional/epilepsy neurosurgery: MR thermometry HIFU; Fluorescence imaging/agents in tumor resection; Intraoperative 3D ultrasound; Intraoperative 3D CT: spine surgery; Intraoperative 3D CT: cranial/functional/trigem; Intraoperative imaging for vascular lesions; Imaging of intraoperative drug delivery; Intraoperative ultrasound for peripheral nerve; and Intraoperative Raman Spectroscopy.

The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. - Presents a comprehensive, translational source of information about the pituitary in one reference work - Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches - Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders - Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches

The management of pituitary adenomas and other sellar tumors is one of the most difficult tasks for neurosurgeons and endocrinologists. Optimal treatment requires a multidisciplinary approach; neurological, ophthalmological, and endocrinological tests are all required. Fortunately, the past decade has seen rapid improvements in the management of patients with pituitary adenomas and other sellar tumors. Transsphenoidal surgery has gone from being an innovative approach to pituitary adenomas to having become the standard procedure for a whole variety of sellar and para-sellar lesions. The authors contributing to this book expertly detail the state-of-the-art treatment of patients with pituitary adenomas, covering operative approaches, peri-operative management, surgical pathology as well as the newer extensions such as image guidance and endoscopy. They also identify the complementary roles of radiosurgery and transcranial surgery in the approach to sellar and suprasellar tumors. In addition the text gives a glimpse at what the future may hold for the treatment of such tumors. The present volume of Frontiers of Hormone Research will be of great value for endocrinologists, neurosurgeons, neuropathologists, neuro-ophthalmologists, and otolaryngologists in the treatment of patients with pituitary adenomas.

Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions. The book stresses the importance of teamwork and has been produced by one of the pioneering groups in the field of endoscopic approaches to the pituitary. It is a useful guide primarily for neurosurgeons and sinonasal endoscopic surgeons but also for other specialists involved in the diagnosis and treatment of skull base lesions.

In this issue of Neurosurgery Clinics, Guest Editor James A. Stadler brings his considerable expertise to the topic of syndromic neurosurgery. Top experts in the field cover key topics such as Syndromic epilepsy, tumor syndromes, syndromic craniosynostosis, and more. - Provides in-depth, clinical reviews on syndromic neurosurgery, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 14 relevant, practice-oriented topics including The history of syndromic neurosurgery; Multidisciplinary evaluation of neurosurgical patients with genetic syndromes; Neurosurgical evaluation and management of children with achondroplasia; Neurosurgical evaluation and management of patients with connective tissue disorders; and more.

In this issue of Neurosurgery Clinics, guest editors Drs. Randy L. Jensen and Gabriel Zada bring their considerable expertise to the topic of Meningioma. Top experts in the field cover key topics such as genomic and epigenomic landscape of meningioma; current pathology of meningiomas; medical management of meningiomas; endoscope endonasal and keyhole surgery for skull base meningiomas; open craniotomy for meningiomas; and more. - Contains 17 relevant, practice-oriented topics including management of intraventricular meningioma; spinal meningiomas; immunotherapy and other targeted therapies for meningiomas; the role of radiotherapy in the treatment of higher-grade meningioma; advanced meningioma imaging; and more. - Provides in-depth clinical reviews on meningioma, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Because the base of the skull has proven to be one of the most challenging regions of the body to access, treatment options were once limited for patients with tumors or lesions in this area. However, with recent advancements and breakthroughs in treatment, patients with skull base tumors now have an array of surgical options that can help them return to leading a normal and active life. The Endoscopic Endonasal Approach (EEA) is an innovative surgical technique used to remove brain tumors and lesions—some as large as softballs—all through the nose.

Atlas of Clinical Gross Anatomy uses over 500 incredibly well-executed and superb dissection photos and illustrations to guide you through all the key structures you'll need to learn in your gross anatomy course. This medical textbook helps you master essential surface, gross, and radiologic anatomy concepts through high-quality photos, digital enhancements, and concise text introductions throughout. - Get a clear understanding of surface, gross, and radiologic anatomy with a resource that's great for use before, during, and after lab work, in preparation for examinations, and later on as a primer for clinical work. - Learn as intuitively as possible with large, full-page photos for effortless comprehension. No more confusion and peering at small, closely cropped pictures! - Easily distinguish highlighted structures from the background in each dissection with the aid of digitally color-enhanced images. - See structures the way they present in the anatomy lab with specially commissioned dissections, all done using freshly dissected cadavers prepared using low-alcohol fixative. - Bridge the gap between gross anatomy and clinical practice with clinical correlations throughout. - Master anatomy efficiently with one text covering all you need to know, from surface to radiologic anatomy, that's ideal for shortened anatomy courses. - Review key structures quickly thanks to detailed dissection headings and unique icon navigation. - Access the full text and self assessment questions at studentconsult.com.