Next Generation Sequencing Ngs Technology In Dna Analysis
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Author |
: Urszula Demkow |
Publisher |
: Academic Press |
Total Pages |
: 336 |
Release |
: 2015-09-10 |
ISBN-10 |
: 9780128018415 |
ISBN-13 |
: 0128018410 |
Rating |
: 4/5 (15 Downloads) |
Synopsis Clinical Applications for Next-Generation Sequencing by : Urszula Demkow
Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies
Author |
: Stuart M. Brown |
Publisher |
: |
Total Pages |
: 0 |
Release |
: 2015 |
ISBN-10 |
: 1621821234 |
ISBN-13 |
: 9781621821236 |
Rating |
: 4/5 (34 Downloads) |
Synopsis Next-generation DNA Sequencing Informatics by : Stuart M. Brown
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"
Author |
: Xinkun Wang |
Publisher |
: CRC Press |
Total Pages |
: 252 |
Release |
: 2016-04-06 |
ISBN-10 |
: 9781482217896 |
ISBN-13 |
: 1482217899 |
Rating |
: 4/5 (96 Downloads) |
Synopsis Next-Generation Sequencing Data Analysis by : Xinkun Wang
A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi
Author |
: Hirak Ranjan Dash |
Publisher |
: Elsevier |
Total Pages |
: 614 |
Release |
: 2023-11-30 |
ISBN-10 |
: 9780323993807 |
ISBN-13 |
: 032399380X |
Rating |
: 4/5 (07 Downloads) |
Synopsis Next Generation Sequencing (NGS) Technology in DNA Analysis by : Hirak Ranjan Dash
Next Generation Sequencing (NGS) Technology in DNA Analysis explains and summarizes next generation sequencing (NGS) technological applications in the field of forensic DNA analysis. The book covers the transition from capillary electrophoresis (CE)-based technique to NGS platforms and the fundamentals of NGS technologies, applications, and advances. Sections provide an overview of NGS technology and forensic science, including information on processing biological samples for forensic analysis, sequence analysis, and data analysis software as well as the analysis of NGS data. The book explores the valuable applications of NGS-based forensic DNA analysis and covers the validations and interpretation guidelines of NGS workflows. With chapter contributions from an international array of experts and the inclusion of practical case studies, this book is a useful reference for academicians and researchers in genetics, biotechnology, bioinformatics, biology, and medicine as well as forensic DNA scientists and practitioners who aim to learn, use, apply, and validate NGS-based technologies. - Describes the fundamentals of NGS and its advances for forensic applications - Explains the transition from CE-based technique to NGS technology - Includes case studies related to NGS and DNA fingerprinting - Explores the future use and applications of NGS technologies
Author |
: Jerzy Kulski |
Publisher |
: BoD – Books on Demand |
Total Pages |
: 466 |
Release |
: 2016-01-14 |
ISBN-10 |
: 9789535122401 |
ISBN-13 |
: 9535122401 |
Rating |
: 4/5 (01 Downloads) |
Synopsis Next Generation Sequencing by : Jerzy Kulski
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
Author |
: Ajay Vora |
Publisher |
: Springer |
Total Pages |
: 345 |
Release |
: 2017-04-21 |
ISBN-10 |
: 9783319397085 |
ISBN-13 |
: 3319397087 |
Rating |
: 4/5 (85 Downloads) |
Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author |
: Pankaj Kumar Arora |
Publisher |
: Springer Nature |
Total Pages |
: 341 |
Release |
: 2019-09-12 |
ISBN-10 |
: 9789811388446 |
ISBN-13 |
: 981138844X |
Rating |
: 4/5 (46 Downloads) |
Synopsis Microbial Technology for the Welfare of Society by : Pankaj Kumar Arora
This book describes various aspects of modern microbiology including microbial enzymes, secondary metabolites, next-generation sequencing, microbial-based biopesticides, microbial-based cancer therapies, biodiesel, and microbial products from fermentation, biodegradation, bioremediation and wastewater treatment. Further, it explains how and why microbes play an important role in preserving the welfare of living beings and the environment. Many bacteria play a significant part in cleaning our environment by detoxifying various xenobiotic compounds, while several microbes produce secondary metabolites that are useful to human beings. The book is divided into 15 chapters that cover various aspects of microorganism-based biotechnology, including recent methodologies such as advanced molecular techniques, as well developments in classical microbiological techniques. The authors also explain how the latest and classical techniques are being used in modern-day microbial biotechnology. All chapters were written by experts from prominent universities, research laboratories, and institutes around the globe. Above all, they focus on recent advances in microbial technology that promote the welfare of living beings and the environment.
Author |
: Richard Durbin |
Publisher |
: Cambridge University Press |
Total Pages |
: 372 |
Release |
: 1998-04-23 |
ISBN-10 |
: 9781139457392 |
ISBN-13 |
: 113945739X |
Rating |
: 4/5 (92 Downloads) |
Synopsis Biological Sequence Analysis by : Richard Durbin
Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
Author |
: Bruce Budowle |
Publisher |
: Academic Press |
Total Pages |
: 753 |
Release |
: 2010-10-27 |
ISBN-10 |
: 9780123820075 |
ISBN-13 |
: 0123820073 |
Rating |
: 4/5 (75 Downloads) |
Synopsis Microbial Forensics by : Bruce Budowle
Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. - A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference - New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few - Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease
Author |
: Mourad Elloumi |
Publisher |
: Springer |
Total Pages |
: 356 |
Release |
: 2017-09-18 |
ISBN-10 |
: 9783319598260 |
ISBN-13 |
: 3319598260 |
Rating |
: 4/5 (60 Downloads) |
Synopsis Algorithms for Next-Generation Sequencing Data by : Mourad Elloumi
The 14 contributed chapters in this book survey the most recent developments in high-performance algorithms for NGS data, offering fundamental insights and technical information specifically on indexing, compression and storage; error correction; alignment; and assembly. The book will be of value to researchers, practitioners and students engaged with bioinformatics, computer science, mathematics, statistics and life sciences.