Living organisms are adapted to their environment. Modern compilers and runtime systems for computer software are no different: as part of a continuous optimization process, they can adapt the execution cycle of a program to the workload it operates on. This thesis brings novel ideas to the software optimization domain. It illustrates methodological and practical contributions that advance the state of the art for performance profiling techniques and adaptive runtime designs, backed by promising experimental results on industrial-strength benchmarks. Part of the results has been presented in flagship programming language venues.

Written in an accessible and easy-to-read style, this cutting-edge book presents advanced solutions to current and future telecommunications optimization problems. The field of telecommunications is growing and changing ever more rapidly, presenting new real-world problems for optimization researchers to address. Telecommunications engineers tend to know all about the problems involved but are often not aware of developments in computer science and artificial intelligence that might solve those problems. This unique book takes a colloborative approach describing the essence of the problems and then the heuristic and adaptive techniques which are now recognised as adept at solving these problems. In addition the emerging technologies in telecommunications and increasing use of the Internet expand the role that advanced heuristic and adaptive methods can play. Topics covered include: Heuristic techniques covering local search methods and population-based search techniques Adaptive computation techniques covering neural computation, fuzzy logic and game theory Practical and successful ways to address problems in network design and planning, routing, protocol design and network management This state-of-the-art book will be an essential resource for optimization researchers needing a wider appreciation of the problems in telecommunications, and indispensable for telecommunications engineers using heuristic and adaptive techniques.

Control Applications of Nonlinear Programming and Optimization presents the proceedings of the Fifth IFAC Workshop held in Capri, Italy on June 11-14, 1985. The book covers various aspects of the optimization of control systems and of the numerical solution of optimization problems. The text also discusses specific applications concerned with the optimization of aircraft trajectories, of mineral and metallurgical processes, of wind tunnels, and of nuclear reactors. The book also considers computer-aided design of control systems. The book is useful to mathematicians, engineers, and computer engineers.

This book constitutes the refereed proceedings of the Third International Conference on Swarm, Evolutionary, and Memetic Computing, SEMCCO 2012, held in Bhubaneswar, India, in December 2012. The 96 revised full papers presented were carefully reviewed and selected from 310 initial submissions. The papers cover a wide range of topics in swarm, evolutionary, memetic and other intelligent computing algorithms and their real world applications in problems selected from diverse domains of science and engineering.

This book constitutes the refereed proceedings of the Second International Symposium on High-Performance Computing, ISHPC'99, held in Kyoto, Japan in May 1999. The 23 revised full papers presented were carefully selected from a total of 61 submissions. Also included are the abstracts of several invited talks and 12 reviewed short papers corresponding to the poster presentations given at the symposium. The papers address many current issues in high-performance computing and communication, regarding hardware and network architectures as well as regarding software and theoretical foundations; also advanced applications are studied in a variety of fields including modeling, visualisation, and computational science.

The 15th Workshop on Languages and Compilers for Parallel Computing was held in July 2002 at the University of Maryland, College Park. It was jointly sponsored by the Department of Computer Science at the University of Ma- land and the University of Maryland Institute for Advanced Computer Studies (UMIACS).LCPC2002broughttogetherover60researchersfromacademiaand research institutions from many countries. The program of 26 papers was selected from 32 submissions. Each paper was reviewed by at least three Program Committee members and sometimes by additional reviewers. Prior to the workshop, revised versions of accepted papers were informally published on the workshop’s website and in a paper proceedings that was distributed at the meeting. This year, the workshopwas organizedinto sessions of papers on related topics, and each session consisted of two to three 30-minute presentations.Based on feedback from the workshop,the papers were revised and submitted for inclusion in the formal proceedings published in this volume. Two papers were presented at the workshop but later withdrawn from the ?nal proceedings by their authors. We were very lucky to have Bill Carlson from the Department of Defense give the LCPC 2002 keynote speech on “UPC: A C Language for Shared M- ory Parallel Programming.” Bill gave an excellent overview of the features and programming model of the UPC parallel programming language.

The disciplines of science and engineering rely heavily on the forecasting of prospective constraints for concepts that have not yet been proven to exist, especially in areas such as artificial intelligence. Obtaining quality solutions to the problems presented becomes increasingly difficult due to the number of steps required to sift through the possible solutions, and the ability to solve such problems relies on the recognition of patterns and the categorization of data into specific sets. Predictive modeling and optimization methods allow unknown events to be categorized based on statistics and classifiers input by researchers. The Handbook of Research on Predictive Modeling and Optimization Methods in Science and Engineering is a critical reference source that provides comprehensive information on the use of optimization techniques and predictive models to solve real-life engineering and science problems. Through discussions on techniques such as robust design optimization, water level prediction, and the prediction of human actions, this publication identifies solutions to developing problems and new solutions for existing problems, making this publication a valuable resource for engineers, researchers, graduate students, and other professionals.

Apply adaptive research to improve results in drug development The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently. With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development. Chapters explore such subjects as: The adaptive concept Design and operational adaptations Sample-size reestimation Agile clinical development Safety and dose finding Statistics in adaptive research, including frequentist and Bayesian approaches Data management technologies The future of clinical development By combining centuries-old intellectual foundations, recent technological advances, and modern management techniques, adaptive research preserves the integrity and validity of clinical research but dramatically improves efficiency.

This volume constitutes the refereed proceedings of the 13th International Conference on Parallel Computing. The papers are organized into topical sections covering support tools and environments, performance prediction and evaluation, scheduling and load balancing, compilers for high performance, parallel and distributed databases, grid and cluster computing, peer-to-peer computing, distributed systems and algorithms, and more.

This IBM® Redbooks® publication focuses on gathering the correct technical information, and laying out simple guidance for optimizing code performance on IBM POWER8® processor-based systems that run the IBM AIX®, IBM i, or Linux operating systems. There is straightforward performance optimization that can be performed with a minimum of effort and without extensive previous experience or in-depth knowledge. The POWER8 processor contains many new and important performance features, such as support for eight hardware threads in each core and support for transactional memory. The POWER8 processor is a strict superset of the IBM POWER7+TM processor, and so all of the performance features of the POWER7+ processor, such as multiple page sizes, also appear in the POWER8 processor. Much of the technical information and guidance for optimizing performance on POWER8 processors that is presented in this guide also applies to POWER7+ and earlier processors, except where the guide explicitly indicates that a feature is new in the POWER8 processor. This guide strives to focus on optimizations that tend to be positive across a broad set of IBM POWER® processor chips and systems. Specific guidance is given for the POWER8 processor; however, the general guidance is applicable to the IBM POWER7+, IBM POWER7®, IBM POWER6®, IBM POWER5, and even to earlier processors. This guide is directed at personnel who are responsible for performing migration and implementation activities on POWER8 processor-based systems. This includes system administrators, system architects, network administrators, information architects, and database administrators (DBAs).