In this issue of Clinics in Perinatology, guest editors Drs. Ravi Mangal Patel and Amy Keir bring their considerable expertise to the topic of Neonatal Transfusion Medicine. Transfusions to neonates convey both benefits and risks, and evidence-based data for possible adverse effects, preterm morbidities, mortality, and neuro-developmental problems associated with transfusions is needed to make decisions for proper care. This issue fills the gap of evidence-based knowledge in order to improve outcomes in patients. - Contains 9 practice-oriented topics including potential mechanisms mediating harm from platelet transfusions in neonates; plasma transfusion in the neonate; neonatal blood banking practices; transfusion in neonatal ECMO; allogenic cord blood transfusion in infants; and more. - Provides in-depth clinical reviews on neonatal transfusion medicine, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Perinatology, guest editors Drs. Heather C. Kaplan and Munish Gupta bring their considerable expertise to the topic of Quality Improvement. In recent years, the growing use of quality improvement (QI) methods to apply evidence-based practices to clinical care has resulted in a greater penetration of QI methods in neonatal intensive care units across the world and a more sophisticated appreciation of how best to use them. This issue provides important updates in these areas as well as looks at the future of QI in perinatology. - Contains 15 practice-oriented topics including frameworks for quality improvement: Lean Six Sigma and the model for improvement in perinatology; sustaining improvement in perinatology; recent progress in global health quality improvement in perinatology; measuring equity for quality improvement in perinatology; pursuing equity for all mothers and newborns through population health: the role of perinatal quality collaboratives; and more. - Provides in-depth clinical reviews on quality improvement in perinatology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Perinatology, guest editors Drs. David K. Stevenson and Gary M. Shaw, along with research scientist Ron J. Wong, bring their considerable expertise to the topic of Preterm Birth. Preterm birth is the leading cause of death among children, with one million children dying due to preterm birth before the age of five years. This issue is a key resource for perinatologists who seek to predict and improve outcomes for preterm births, providing actionable clinical information in hopes of reaching the United Nations Sustainable Development Goal to end all preventable deaths of newborns and children aged under five years by 2030. - Contains 15 practice-oriented topics including genomics of preterm birth; predicting preterm birth using proteomics; predicting preterm birth using the microbiome; predicting preterm birth using the immunome; a new taxonomy of preterm birth; and more. - Provides in-depth clinical reviews of preterm birth, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Perinatology, guest editors Akhil Maheshwari and Jonathan R. Swanson bring their considerable expertise to the topic of Neonatal and Perinatal Nutrition. Top experts in the field cover key topics such as nutritional assessment, genomics and nutrient needs, lipids and fatty acids, glucose homeostasis, and more. - Contains 16 relevant, practice-oriented topics including maternal nutrition and fetal/infant development; infant nutrition in the developing world; short bowel syndrome and motility; malabsorption syndromes and food intolerance; and more. - Provides in-depth clinical reviews on neonatal and perinatal nutrition, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Perinatology, guest editor Dr. Lina Chalak brings her considerable expertise to the topic of Perinatal Asphyxia: Moving the Needle. Top experts discuss current clinical information on perinatal asphyxia, giving perinatologists they guidance they need to improve outcomes in newborns, while looking at results from clinical trials, neuroimaging biomarkers, and low-resource settings. - Contains 15 practice-oriented topics including the role of a maternal-placental-fetal triad; treating seizures and improving newborn outcomes; advances in neuroimaging biomarkers and scoring; moving the needle in low-resource settings: is hypothermia a friend or foe?; ethical and medicolegal perspectives on cooling: where to draw the line?; and more. - Provides in-depth clinical reviews of perinatal asphyxia, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Together with Consulting Editor Dr. William Rayburn, Guest Editors Dr. Cynthia Gyamfi-Bannerman and Dr. Russel Miller have curated a state-of-the-art monograph devoted to Advances in Maternal Fetal Medicine. They have secured expert authors to submit clinical reviews for perinatologists. Specific articles are devoted to the following topics: Advances in delivery management for the preterm fetus (magnesium sulfate, late-preterm antenatal corticosteroids); Approaches to stillbirth prevention; Current preterm birth prevention strategies; Neurological outcomes after fetal therapy for complicated monochorionic twins; Innovations in fetal myelomeningocele (fMMC) repair; An update on biologic agents in pregnancy; Telemedicine in obstetrics; The impact of racial and socioeconomic disparities on obstetrical outcomes; Opioids use and misuse in pregnancy; Advances in statewide and national obstetrical QI collaborations; Optimizing term delivery timing and mode of delivery; Preeclampsia; E-Z infections can be quite challenging: Contemporary understanding of Ebola and Zika virus in pregnancy; and Next-generation genetic testing in obstetrics. Readers will come away with the evidence-based recommendations they need to improve patient outcomes.maternal fetal medicine; fetus; pregnancy;

In this issue of Clinics in Perinatology, guest editors Drs. Brenda Poindexter and Amy B. Hair bring their considerable expertise to the topic of Neonatal Nutrition. Emphasizing evidence to support clinical decision making, top experts in the field discuss important topics in the nutrition of neonates with the goals of reducing infant mortality and morbidity. - Contains 14 practice-oriented topics including maternal diet for babies in the NICU; myths and fallacies about feeding healthy term and late-preterm infants during neonatal transition; enteral nutrition: evidence for feeding practices; post-NEC nutrition; nutrition management of high-risk neonates after discharge; and more. - Provides in-depth clinical reviews of neonatal nutrition, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Perinatology, Guest Editors Anup Katheria and Lisa Stellwagen bring their considerable expertise to the topic of Care for the Term Newborn. Top experts in the field cover key topics such as delivery room triage and transitions of care; early onset sepsis; congenital infections; postnatal screening & testing; and more. - Provides in-depth, clinical reviews on Care for the Term Newborn, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 14 relevant, practice-oriented topics including Umbilical Cord Management for vigorous and non-vigorous infants; Fetal Circulation and Critical Congenital Cardiac Disease; Alternative Birth Practices, Refusal, and Therapeutic Hesitancy; Prenatal Substance Exposure; and more.

In this issue of Clinics in Perinatology, guest editors Drs. Nathalie Maitre and Andrea F. Duncan bring their considerable expertise to the topic of Neurological and Developmental Outcomes of High-Risk Neonates. Preterm birth complications are the leading cause of death among children under five years of age, and three-quarters of these deaths could be prevented with current, cost-effective interventions. In this issue, top experts provide neonatologists and perinatologists with the clinical information they need to improve outcomes in high-risk newborns. - Contains 15 practice-oriented topics including neonatal opioid withdrawal syndrome; healthcare disparities in high-risk neonates; autism spectrum and high-risk infant phenotypes; NICU transition to home interventions; telehealth and other innovations in NICU follow up; and more. - Provides in-depth clinical reviews on neurological and developmental outcomes of high-risk neonates, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Perinatology, guest editors Drs. Ravi Mangal Patel and Amy Keir bring their considerable expertise to the topic of Neonatal Transfusion Medicine. Transfusions to neonates convey both benefits and risks, and evidence-based data for possible adverse effects, preterm morbidities, mortality, and neuro-developmental problems associated with transfusions is needed to make decisions for proper care. This issue fills the gap of evidence-based knowledge in order to improve outcomes in patients. Contains 9 practice-oriented topics including potential mechanisms mediating harm from platelet transfusions in neonates; plasma transfusion in the neonate; neonatal blood banking practices; transfusion in neonatal ECMO; allogenic cord blood transfusion in infants; and more. Provides in-depth clinical reviews on neonatal transfusion medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.