New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.

Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices covers the modern micro and nanotechnologies used for diagnosis, drug delivery, and theranostics using micro, nano, and implantable systems. In-depth coverage of all aspects of disease treatment is included. In addition, the book covers cutting-edge research and technology that will help readers gain knowledge of novel approaches and their applications to improve drug/agent specificity for diagnosis and efficient disease treatment. It is a comprehensive guide for medical specialists, the pharmaceutical-industry, and academic researchers discussing the impact of nanotechnology on diagnosis, drug delivery, and theranostics. - Gives readers working in immunology, drug delivery, and medicine a greater awareness on how novel nanotechnology orientated methods can help improve treatment - Provides readers with backgrounds in nanotechnology, chemistry, and materials science an understanding on how nanotechnology is used in immunology and drug delivery - Includes focused coverage of the use of nanodevices in diagnostics, therapeutics, and theranostics not offered by other books

Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications.

New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.

Several micro- and nanomanipulation techniques have emerged in recent decades thanks to advances in micro- and nanofabrication. For instance, the atomic force microscope (AFM) uses a nano-sized tip to image, push, pull, cut, and indent biological material in air, liquid, or vacuum. Using micro- and nanofabrication techniques, scientists can make manipulation tools, such as microgrippers and nanotweezers, on the same length scale as the biological samples. Micro and Nano Techniques for the Handling of Biological Samples reviews the different techniques available to manipulate and integrate biological materials in a controlled manner, either by sliding them along a surface (2-D manipulation), or by gripping and moving them to a new position (3-D manipulation). The advantages and drawbacks are mentioned together with examples that reflect the state-of-the-art in manipulation techniques for biological samples. Thanks to the advances in micro- and nanomanipulation techniques, the integration of biomaterials with physical transducers has been possible, giving rise to new and highly sensitive biosensing devices. Although great progress has been made, challenges are still present. To understand the complex interactions between and inside biological samples, scientists will always be working on improving technologies to manipulate, transport, sort, and integrate samples in different environments. Balanced between simplicity for the beginner and hardcore theory for the more advanced readers, this book is the ideal launching point for sharpening the scientific tools required to address these challenges.

Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies. - Highlights the relevance of oral drug delivery in the clinical setting - Covers the most recent advances in the field of nanotechnology for oral drug delivery - Provides the scientific community with data that can facilitate and guide their research

Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications. It has the potential to revolutionize drug therapy by making treatments more effective, reducing side effects, and improving patient outcomes. This book presents a comprehensive review of the most recent studies on smart micro- and nanomaterials with a focus on their “smart” activity for formation of targeted and responsive drug-delivery carriers. This volume: Introduces readers to the fundamentals of these the micro- and nanoscale materials as well as approaches to smart drug delivery and drug delivery systems. Covers polymers, metals, and composite materials as well as quantum dots and carbon nanotubes. Describes of all possible stimulated systems for drug delivery such as enzyme-responsive, small molecules-responsive, thermo-responsive, pH-responsive, electric field-responsive, magnetic field-responsive, light-responsive, ultrasound-responsive, and reductive environment responsive. Offers a critical perspective on the future scope of smart drug delivery systems. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.

Smart drug delivery refers to a targeted drug delivery or precision drug delivery system that allows drugs to be administered to a specific location in the body or at a specific time with enhanced precision and control. This approach has several advantages, including maximizing the therapeutic effects of a drug while minimizing side effects. This book presents various stimuli-responsive micro- and nanomaterials for pharmaceutical industries. This volume: Covers the global market perspective of micro- and nano-smart materials in pharmaceutical industries. Details various processing routes. Discusses mechanisms for target release. Addresses applications in oral drug delivery, anticancer agents, anti-tumor drug delivery, and drugs for management of infection. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.

Nanomedicine explores the modification and enhancement of the properties and performances of typical drugs to treat various diseases. Nano-based medicines have advantages in several ways, such as in nanotherapeutics, nanotheranostics, and nanodiagnostics. Nanomedicine Manufacturing and Applications effectively explores the major manufacturing techniques and applications of nanomaterial-based medicine in the areas of chemotherapy, biochips, insulin pumps, and other treatment methods. This book explains how nanomedicines are developed from nanoparticles as well as their biomedical and other applications related to healthcare. This book is an important reference source for nanoscientists, biomaterials scientists, and biomedical engineers who want to learn more about how nano-based medicines are made and used. - Outlines the process of making nanomedicine as well as nanodrug carriers, with a focus on nanomedicine for cancer treatment. - Explains the formulation and manufacturing process of nanomedicines, showing how to build these materials. - Demonstrates how nano-based medicines are being used to tackle a range of diseases in a way that conventional medicines cannot.