This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts sheet format. Database accession numbers and useful adjuncts such as Request forms, worksheets for PCR/enzyme digests also serve to benefit the user. The information is clearly presented and easily accessible and is complemented by the excellent diagrams and tabular material. This book is invaluable for both new and experienced researchers in the field and other related disciplines. - Essential for hematologists and those involoved in tissue typing and the study of human genetic polymorphisms - Presents clearly and concisely the information on a particular variant and the technique used to detect it - Organized by antigen and provides sequences of polymorphisms and primers - Details the general concepts and critical information on genes, their products, and sources of relevant nucleic acids - Includes protocols that allow investigators to set up assays with minimal effort (protocols include primers, reagents, reaction conditions, sizes of amplified products, restriction fragment digests, and the relevant safety information) - Provides information that helps interpret results in clinical settings - Contains additional sources of information (e.g., key references, web site addresses, glossary, Database accession numbers, request forms, and worksheets for PCR/enzyme digests)

Offering a concise overview of transfusion medicine, including best practices for specific clinical settings, this practical resource by Dr. Robert W. Maitta covers the key information you need to know. Holistic, multidisciplinary coverage and a succinct, easy-to-read format make it essential reading for transfusion specialists, as well as practitioners in other specialties whose patients undergo blood transfusions. - Covers the latest advancements in transfusion therapies, hematopoietic stem cells, infectious and non-infectious complications of transfusions, and future directions in transfusion medicine. - Discusses special populations, including organ transplant patients; pediatric, obstetric, and geriatric patients; and patients undergoing emergency care. - Consolidates fundamental clinical concepts and current practice of transfusion medicine into one convenient resource.

Practical Transfusion Medicine, Fourth Edition Edited by Michael F. Murphy, Professor of Blood Transfusion Medicine, University of Oxford; Consultant Haematologist, NHS Blood and Transplant and Oxford University Hospitals, Oxford, UK Derwood H. Pamphilon, formerly Consultant Haematologist, NHS Blood and Transplant; Honorary Clinical Reader, Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK Nancy M. Heddle, Director, MTRP, Professor, Department of Medicine, McMaster University, Hamilton, Ontario, Canada The pace of change in transfusion medicine is relentless, with new scientific and technological developments. In addition, efforts are continuing to improve clinical transfusion practice and avoid the use of blood wherever possible. This fourth edition continues to be a concise and comprehensive guide to transfusion medicine. It has been thoroughly revised and updated throughout. The scope of the book has been broadened by including more international authors and a new co-editor, Professor Nancy Heddle, an expert in evidence-based transfusion medicine. Practical Transfusion Medicine is divided into seven main parts, each of which guide the reader systematically through the key areas of the speciality: - Principles of transfusion medicine - Complications of transfusion - Practice in blood centres and hospitals - Clinical transfusion practice - Alternatives to transfusion - Cellular and tissue therapy and organ transplantation - Development of the evidence base for transfusion This book is ideal for trainee/resident haematologists revising for examinations and as a reference source for clinical and scientific staff working in the field of transfusion medicine. Titles of related interest Klein: Mollison’s Blood Transfusion in Clinical Medicine, 11e ISBN 9780632064540 (forthcoming 2013) De Vries: Hemovigilance: An Effective Tool for Improving Transfusion Safety ISBN 9780470655276 (August 2012) McCullough: Transfusion Medicine, 3e ISBN 978144433705 (December 2011)

The objective of this publication is to set out a balanced view of current opinion about good clinical practice for blood transfusion services in the UK, giving, where possible, an evidence-based account about effective treatment. It is intended for all staff involved in prescribing, supplying and administering blood products, and will also be useful to medical, laboratory and nursing staff and those responsible for the safe transport and delivery of blood to the patient. This is the 5th edition of this publication and it supersedes the 4th ed. (2007) (ISBN 9780113226771).

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Handbook of Transfusion Medicine

Highly Commended - 2010 BMA Medical Book Awards An essential, practical manual for all those working in transfusion medicine Concise and user-friendly guide to transfusion medicine Focuses on clinical aspects but also covers background science and organizational issues Complications encountered in transfusion are addressed throughout Highlights controversial issues and provides advice for everyday clinical questions in transfusion medicine This comprehensive guide to transfusion medicine takes a practical and didactic approach. The third edition of this text includes many new contributions and has expanded to seven sections. The first of these takes the reader systematically through the principles of transfusion medicine. The second deals with the complications which can arise in transfusion and is followed by a section on the practice of transfusion in blood centres and hospitals. The fourth section covers clinical transfusion practice and the fifth looks at alternatives to transfusion. Section six addresses cellular and tissue therapy and organ transplantation and the final section of the book examines the development of the evidence base for transfusion. As with previous editions; the final section includes a visionary chapter on future advances in the field. This new edition of Practical Transfusion Medicine benefits from even more international authorship than the previous two editions and is an invaluable resource for trainee doctors, scientists, technicians and other staff in haematology and transfusion and as a reference book for clinical staff in haematology and other disciplines faced with specific problems.

Commonly known as the Red Book, Guidelines for the Blood Transfusion Services in the United Kingdom 8th Edition contains best practice guidelines for all materials produced by the United Kingdom Blood Transfusion Services (UKBTS) for both therapeutic and diagnostic use. Key features: Sets standards to be met, describes technical details of processes and states legally binding requirements under Blood Safety and Quality Regulations 2005; Reflects the work of Joint UKBTS/HPA Professional Advisory Committee (JPAC) experts with the overall aim of ensuring as far as possible the safety of Blood transfusion for both donor and patient in the UK;Focuses on products rather than their use

This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.