Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. This popular primer provides a solid understanding of the nervous system, neurologic disorders, and treatments with drugs and other substances Nestler, Hyman, and Malenka’s Molecular Neuropharmacology, Fourth Edition covers everything you need to know about molecular neuroscience. This meticulously detailed guide provides a deep dive into the pathophysiology of neurologic and psychiatric disorders by describing neuropharmacological fundamentals of the nervous system. Packed with tables, diagrams, and figures making the intricacies of neurochemistry easy to understand, it builds a solid understanding of major disease mechanisms by reviewing the effects of drug actions (organized by drug category), and it explains the neuropharmacology of specific neural and psychiatric disorders. Concise overviews of the effects of drugs and neurologically active substances appear before the descriptions of the minute details that lead to these effects—a format designed to boost understanding and knowledge retention of critical concepts.

Market: Pharmacy and medical students; neuroscientists; neurologists; pharmacologists Updated edition has an attractive full-color design with more illustrations Includes numerous Fact Boxes to help reinforce learning

GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others. The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations. FEATURES NEW chapter on neuroinflammation All chemical structure illustrations have been redrawn and improved Fully updated to reflect the latest breakthroughs and new drugs The most well-written and easily understood work on the subject More than 300 full-color illustrations!

* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine

* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine.

Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475

The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.

* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

A COMPREHENSIVE, FULL-COLOR GUIDE TO NEURORADIOLOGY SIGNS ACROSS ALL IMAGING MODALITIES The first book of its kind, Neuroradiology Signs provides a multimodality review of more than 440 neuroradiologic signs in CT, MR, angiography, radiography, ultrasound, and nuclear medicine. It is designed to enhance your recognition of specific imaging patterns, enabling you to arrive at an accurate diagnosis. Neuroradiology Signs consists of 7 chapters: Adult and General Brain Pediatric Brain Head, Neck, and Orbits Vascular Skull and Facial Bones Vertebrae Spinal Cord and Nerves All cases have been reviewed by subspecialty experts and include: Imaging Findings Modalities Differential Diagnosis Discussion References Full-color photographs illustrate sign etymology and enhance your learning experience. The index is conveniently organized by sign, diagnosis, and modality. Neuroradiology Signs is a valuable review for trainees preparing for board examinations and a trusted daily reference for practicing clinicians.