Routine applications of advanced statistical methods on real data have become possible in the last ten years because desktop computers have become much more powerful and cheaper. However, proper understanding of the challenging statistical theory behind those methods remains essential for correct application and interpretation, and rarely seen in the medical literature. Modern Methods for Epidemiology provides a concise introduction to recent development in statistical methodologies for epidemiological and biomedical researchers. Many of these methods have become indispensible tools for researchers working in epidemiology and medicine but are rarely discussed in details by standard textbooks of biostatistics or epidemiology. Contributors of this book are experienced researchers and experts in their respective fields. This textbook provides a solid starting point for those who are new to epidemiology, and for those looking for guidance in more modern statistical approaches to observational epidemiology. Epidemiological and biomedical researchers who wish to overcome the mathematical barrier of applying those methods to their research will find this book an accessible and helpful reference for self-learning and research. This book is also a good source for teaching postgraduate students in medical statistics or epidemiology.

The thoroughly revised and updated Third Edition of the acclaimed Modern Epidemiology reflects both the conceptual development of this evolving science and the increasingly focal role that epidemiology plays in dealing with public health and medical problems. Coauthored by three leading epidemiologists, with sixteen additional contributors, this Third Edition is the most comprehensive and cohesive text on the principles and methods of epidemiologic research. The book covers a broad range of concepts and methods, such as basic measures of disease frequency and associations, study design, field methods, threats to validity, and assessing precision. It also covers advanced topics in data analysis such as Bayesian analysis, bias analysis, and hierarchical regression. Chapters examine specific areas of research such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, and clinical epidemiology.

This book examines statistical methods and models used in the fields of global health and epidemiology. It includes methods such as innovative probability sampling, data harmonization and encryption, and advanced descriptive, analytical and monitory methods. Program codes using R are included as well as real data examples. Contemporary global health and epidemiology involves a myriad of medical and health challenges, including inequality of treatment, the HIV/AIDS epidemic and its subsequent control, the flu, cancer, tobacco control, drug use, and environmental pollution. In addition to its vast scales and telescopic perspective; addressing global health concerns often involves examining resource-limited populations with large geographic, socioeconomic diversities. Therefore, advancing global health requires new epidemiological design, new data, and new methods for sampling, data processing, and statistical analysis. This book provides global health researchers with methods that will enable access to and utilization of existing data. Featuring contributions from both epidemiological and biostatistical scholars, this book is a practical resource for researchers, practitioners, and students in solving global health problems in research, education, training, and consultation.

Hardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro’s and con’s of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and overreaction of the public, we need solid scientific knowledge and an understanding of all aspects of infectious diseases and their control. The aim of our book is to present the reader with the general picture and the main ideas of the subject. The book introduces the reader to methodological aspects of epidemiology that are specific for infectious diseases and provides insight into the epidemiology of some classes of infectious diseases characterized by their main modes of transmission. This choice of topics bridges the gap between scientific research on the clinical, biological, mathematical, social and economic aspects of infectious diseases and their applications in public health. The book will help the reader to understand the impact of infectious diseases on modern society and the instruments that policy makers have at their disposal to deal with these challenges. It is written for students of the health sciences, both of curative medicine and public health, and for experts that are active in these and related domains, and it may be of interest for the educated layman since the technical level is kept relatively low.

"This book provides information regarding epidemiologic methods used in studies of physical activity. It is intended for use by students and researchers in physical activity and in public health, and by researchers and professionals using physical activity data (e.g., exercise physiologists and health economists). Additionally, those interested in physical activity and health, who want to understand and appropriately interpret the results of physical activity studies (e.g., physicians and journalists), may also find the book useful."--BOOK JACKET.

The concepts of epidemiology, the science that uses statistical methods to investigate associations between risk factors and disease outcomes in human populations, are developed using examples involving real data from published studies. The relevant statistical methods are developed systematically to provide an integrated approach to observational and experimental studies. After covering basic measurement, study design, and study credibility issues, the author continues with basic statistical methods and techniques for adjusting risk estimates for confounders. Statistical models including logistic regression and the proportional hazards model for survival analysis are explained in detail in the following chapters, concluding with an explanation of the general methods for determining the sample size and power requirements for an epidemiological study. Taking advantage of the power, accessibility and user-friendliness of modern computer packages, the author uses a variety of interesting data sets and graphical displays to illustrate the methods. Epidemiological Research Methods will be of interest to students and research workers who need to learn and appreciate modern approaches to the subject. Without unnecessary emphasis on mathematics or theory, the book will enable the reader to gain a greater level of understanding of the underlying methods than is normally provided in books on epidemiology.

This second edition of Epidemiologic Methods offers a rigorous introduction to the concepts and tools of epidemiologic research. Aimed chiefly at future epidemiologists, the book offers clear descriptions, practical examples, and question/answer sections for each of the science's key concepts. Authored by two award-winning epidemiology instructors, this book is ideally suited for use as a text in a graduate-level course sequence in epidemiologic methods. The book's chapters are organized around three main themes: general concepts and tools of epidemiology; major study designs; and special topics, including screening, outbreak investigations, and use of epidemiology to evaluate policies and programs. With additional exercises at the end of each chapter and expanded attention to topics such as confounding, this new edition of Epidemiologic Methods is an indispensable resource for the next generation of epidemiologic study.

Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet

This is the second edition of the first book to provide a complete picture of the design, conduct and analysis of observational studies, the most common type of epidemiologic study. Stressing sample size estimation, sampling, and measurement error, the authors cover the full scope of observational studies, describing cohort studies, case-control studies, cross-sectional studies, and epidemic investigation. The use of statistical procedures is described in easy-to-understand terms.

This book describes the variety of direct and indirect population size estimation (PSE) methods available along with their strengths and weaknesses. Direct estimation methods, such as enumeration and mapping, involve contact with members of hard-to-reach groups. Indirect methods have practical appeal because they require no contact with members of hard-to-reach groups. One indirect method in particular, network scale-up (NSU), has several strengths over other PSE methods: It can be applied at a province/country level, it can estimate size of several hard-to-reach population in a single study, and it is implemented with members of the general population rather than members of hard-to-reach groups. The book discusses methods to collect, analyze, and adjust results and presents methods to triangulate and finalize PSEs.