In consultation with Consulting Editor, Dr. Charles Lightdale, Dr. Kenneth Chang has assembled top authors to provide a current update on the management of GERD. Clinical review articles provide updates on the these important topics: Mechanism and Pathophysiology of GERD; Personalized Approach in the work-up and management of GERD; Proton Pump Inhibitors; Radiofrequency Treatment for GERD; Trans-oral Incisionless Fundoplication (TIF); Innovations in Endoscopic Therapy for GERD; Laparoscopic Hernia Repair and Fundoplication, Failed Nissen; Laparoscopic Sphincter Augmentation (LINX); Refractory GERD and Functional Heartburn; and Extra-esophageal GERD and LPR. Readers will come away with the latest techniques and clinical applications to improve patient outcomes.

THE ESOPHAGUS The Esophagus investigates the anatomy, physiology, and pathology of the esophagus. This sixth edition, revised and updated throughout, also explores the diagnosis and treatment of various esophageal conditions. It includes treatment guidelines approved by the two largest gastroenterology societies, the ACG and AGA, as befits a work co-edited by two former presidents of those organizations. Advancements in diagnostics are presented, as are developments in the surgical and drug therapies. Presented in full colour, and boasting an unrivalled team of editors and contributing authors, The Esophagus Sixth Edition will find a home wherever the anatomy, physiology, and pathology of the esophagus are studied and taught. This book is accompanied by a website containing all the figures from the book in PowerPoint format. www.wiley.com/go/richter/esophagus6e Praise for the Fifth Edition: “There is absolutely no doubt that this edition of the textbook will maintain its status as the go-to reference for esophageal conditions, and will remain a highly utilized and clinically useful resource for novice and experienced physicians and surgeons alike.” (Gastroenterology, 1 July 2013)

This book presents a new, multi- and interdisciplinary approach to gastroesophageal reflux disease (GERD) and Barrett’s esophagus that reflects the latest advances in understanding of the disease. The role of each of the available diagnostic techniques, including endoscopy, histopathology, esophageal manometry, reflux monitoring, and EndoFLIP assessment, is carefully explained. The use of endoscopy for the purposes of mucosal ablation (radiofrequency ablation, cryoablation) and mucosal resection is described, and all aspects of anti-reflux surgery are covered, with detailed explanation of indications and techniques for standard fundoplication, endoscopic fundoplication, and surgical procedures using the LINX system and the EndoStim device. To assist the reader further, a novel interdisciplinary algorithm is presented for GERD diagnosis and treatment. In addition, the latest diagnostic and therapeutic approaches (including endoscopic and surgical resection and chemoradiation) are also presented for esophageal cancer and cancer palliation. A key feature of the book is its recognition of the contribution of different specialties in the management of GERD, and it will accordingly appeal to a wide range of practitioners.

This portable handbook provides daily guidance on one of the most prevalent conditions in medicine, gastroesophageal reflux disease and related acid-reflux conditions. Gastroenterologists in training and in practice will use the variety of pedagogic features -- such as case histories, potential pitfall boxes, key points, management algorithms, and useful weblinks -- in each chapter to find quick answers to immediate questions.

Today a number of gastrointestinal disorders that once required open surgical or percutaneous management are being managed with endolumenal therapies. This has led to an evolution of minimally invasive endolumenal approaches to many disorders. This issue reviews the progress made in the application of endolumenal therapies and not only discuss current applications but future efforts and directions for clinical investigation. Articles will focus on the scope of the problem, past management options, new endolumenal options, investigations with endolumenal therapy, current status (clinical trial results if available), and future directions.

In collaboration with Consulting Editor, Dr. Charles J. Lightdale, Guest Editor Dr. Sachin Wani has put together a state-of-the art issue that presents the latest advances in Barrett's Esophagus. He has secured expert authors who have contributed clinical reviews on the following topics: The epidemiology of Barrett's esophagus and esophageal adenocarcinoma – implications for screening and surveillance; Endoscopic screening for Barrett's esophagus and esophageal adenocarcinoma: rationale, candidates and challenges; Progress in screening for Barrett's esophagus: beyond standard upper endoscopy; Best practices in surveillance for Barrett's esophagus; Pathologic assessment of Barrett's esophagus and Barrett's related neoplasia: Do we need quality indicators; Cost effectiveness of screening, surveillance and endoscopic eradication therapies in Barrett's esophagus and early esophageal cancer; Advanced imaging and sampling in Barrett's esophagus: Artificial intelligence to the rescue; Advances in biomarkers for risk stratification in Barrett's esophagus; Current status of chemoprevention in Barrett's esophagus; Optimizing outcomes with radiofrequency frequency ablation of Barrett's esophagus: candidates, efficacy and durability; Updates in cryotherapy for Barrett's esophagus; Role of endoscopic mucosal resection and endoscopic submucosal dissection in the management of Barrett's related neoplasia; Practical approach to refractory and recurrent Barrett's esophagus; Surgical management of Barrett's related neoplasia; and Measuring Quality in Barrett's esophagus: Time to embrace quality indicators. Endoscopists will come away with the information they need to screen, diagnose, and treat patients with Barrett's Esophagus.

Gastroesophageal reflux disease and its complications effect 40 % of the US population. It is the most common reason for outpatient GI visits with treatment costs amounting to nearly $10 billion a year. Thisissue updates interested physicians on the new advance in GERD pathogenesis, diagnosis and medical/surgical treatment , especially over the last 5 years. Lots of advancements have been made in this time period and this will be a excellent reference book for the busy academic and community physician interested in GERD.

In collaboration with Consulting Editor, Dr. Charles Lightdale, Dr. Douglas K. Rex has put together a state-of the-art issue of the Gastrointestinal Endoscopy Clinics of North America devoted to Colonoscopic Polypectomy. Expert authors have contributed clinical reviews that address best practices, evidentiary support, and expert recommendations. Articles specifically address the following topics: Endoscopic assessment prior to resection: What the experts do; Reviewing the evidence that polypectomy prevents cancer; The cold revolution: how far can it go?; Best methods for resection of diminutive and small polyps; Teaching polypectomy and assessing the quality of polypectomy; How to perform wide-field EMR and follow-up examinations; Surgery vs. EMR vs. ESD for large polyps: Making sense of when to use which approach; How to learn and perform ESD and full thickness endoscopic resection in the colorectum in the U.S; Underwater endoscopic mucosal resection (EMR); Lesion retrieval, lesions handling, marking; and Closure of defects and management of complications. Readers will come away with the latest information they need to evaluate options for lesion resection and to improve outcomes.

Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.