How the controversial practice of quarantine saved nineteenth-century Philadelphia after a series of deadly epidemics. In the 1790s, four devastating yellow fever epidemics threatened the survival of Philadelphia, the nation's capital and largest city. In response, the city built a new quarantine station called the Lazaretto downriver from its port. From 1801 to 1895, a strict quarantine was enforced there to protect the city against yellow fever, cholera, typhus, and other diseases. At the time, the science behind quarantine was hotly contested, and the Board of Health in Philadelphia was plagued by internal conflicts and political resistance. In Lazaretto, David Barnes tells the story of how a blend of pragmatism, improvisation, and humane care succeeded in treating seemingly incurable diseases and preventing further outbreaks. Barnes shares the lessons of the Lazaretto through a series of tragic and inspiring true stories of people caught up in the painful ordeal of quarantine. They include a nine-year-old girl enslaved in West Africa and freed upon arrival in Philadelphia, an eleven-year-old orphan boy who survived yellow fever only to be scapegoated for starting an epidemic, and a grieving widow who saved the Lazaretto in the midst of catastrophe. Spanning a turbulent century of immigration, urban growth, and social transformation, Lazaretto takes readers inside the life-and-death debates and ordinary heroism that saved Philadelphia when its survival as a city was at stake. Amid the controversy and tragedy of the COVID-19 pandemic, this surprising reappraisal of America's historic struggle against deadly epidemics reminds us not to neglect old knowledge and skills in our rush to embrace the new.

After a pandemic strikes, a dorm complex at a small American college is quarantined with all of the students trapped within. What first starts out as youthful freedom from authority soon devolves into a violent new society—it's Lord of the Flies on a college campus. From writer Clay McLeod Chapman (Spider-Verse, Ultimate Spider-Man, American Vampire, Vertigo Quarterly), whose most recent play, “Stump Speeches,” was a New York Times Critics' Pick; and introducing artist Jey Levang.

“Vibrant. . . . Completely engaging. . . . A unique blend of poetic language and graphic depictions of the injustices suffered by African Americans in the post-Civil War period.”— Booklist (starred review) Diane McKinney-Whetstone's stunning historical novel, Lazaretto, begins in the chaotic back streets of post-Civil War Philadelphia as a young black woman, Meda, gives birth to a child fathered by her wealthy white employer. In a city riven by racial tension, the father’s transgression is unforgivable. He arranges to take the baby, so it falls to Sylvia, the midwife’s teenage apprentice, to tell Meda that her child is dead—a lie that will define the course of both women’s lives. A devastated Meda dedicates herself to working in an orphanage and becomes a surrogate mother to two white boys; while Sylvia, fueled by her guilt, throws herself into her nursing studies and finds a post at the Lazaretto, the country’s first quarantine hospital, situated near the Delaware River, just south of Philadelphia. The Lazaretto is a crucible of life and death; sick passengers and corpses are quarantined here, but this is also the place where immigrants take their first steps toward the American dream. The live-in staff are mostly black Philadelphians, and when two of them arrange to marry, the city’s black community prepares for a party on its grounds. But the celebration is plunged into chaos when gunshots ring out across the river. As Sylvia races to save the victim, the fates of Meda’s beloved orphans also converge on the Lazaretto. Here conflicts escalate, lies collapse, and secrets begin to surface. Like dead men rising, past sins cannot be contained.