AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical app

The Pathology of Drug Abuse, Second Edition is a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book also offers detailed information on the origin, history, and production techniques used to make these drugs. As in the first edition, emphasis remains focused on the investigation of drug-related deaths and on practical approaches to the detection of drug abuse. The medical complications associated with each of the abused drugs are discussed in some detail as well. Individual chapters deal with cocaine, other naturally occurring stimulants, synthetic stimulants, hallucinogens, narcotics, anabolic steroids, and solvent abuse. Approximately 800 new references have been added since the publication of the first edition. Numerous new photomicrographs and drawings have been added, and many of the illustrations from the first edition have been redrawn to enhance clarity.

Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the

Written in the same accessible manner as previous editions, the fifth edition of Karch‘s Pathology of Drug Abuse is an essential guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book focuses on the investigation of drug-related deaths, practical approaches to the detection of drug abuse, and discussions of medical

Provides a self-teaching reference text for forensic chemistry laboratories and law enforcement agencies world-wide. The text includes sections on the importance of physical examinations of drugs and their wrappings; and the use of gas and high-performance chromatography.

A Brief History of Cocaine, Second Edition provides a fascinating historical insight into the reasons why cocaine use is increasing in popularity and why the rise of the cocaine trade is tightly linked with the rise of terrorism The author illustrates the challenges faced by today's governments and explains why current anti-drug efforts have had on

Prenatal Cocaine Exposures addresses the timely problem of maternal cocaine abuse and its effects on exposed infants, including growth retardation, learning, cardiovascular effects, and seizures. The impact of substance abuse on this and future generations presents an ongoing challenge to medical science. This comprehensive and authoritative volume reviews both animal and clinical studies to explain implications for treatment and long-term outcomes of early exposure. Prenatal Cocaine Exposures investigates the specific role of cocaine in altering fetal development. Discussions of current studies and state-of-the-art techniques provide a basis for informed clinical decisions. Pediatricians, medical specialists, basic scientists, educators, and policy makers will all benefit from the comprehensive research gathered in this volume.

A man is accused of attempted murder of a former crystal meth addict. He claims he shot in self-defense, responding to the extremely aggressive behavior the victim was exhibiting. How will this play out in court? Most likely, the prosecution and the defense will call various expert witnesses - perhaps neurologists, psychologists, pathologists - each with testimonies based on their own theoretical viewpoints, but none with a truly comprehensive knowledge of the background and effects of methamphetamine (MA) use. This will cause confusion, complexity, and their testimonies may not comply with Daubert standards. Written by a multidisciplinary team of experts, Methaphetamine Use: Clinical and Forensic Aspects examines MA use and abuse from clinical, forensic, and criminal justice perspectives. It is the first to cover virtually every aspect, reviewing the history, pharmacology, pathology, physiology, treatment, and evidentiary value of MA and its use. It addresses Daubert considerations and victim/witness credibility, competency to confess and to stand trial, criminal responsibility, extreme emotion as mitigation to murder, and dangerousness. It also details statutes and case law to represent perspectives of both the prosecution and the defense. Growing in popularity more than any other illegal drug, methamphetamine has been shown to produce a paranoid psychotic state, which may recur months or years after use. Methamphetamine Use: Clinical and Forensic Aspects provides a comprehensive, critical survey of the current knowledge and policies regarding the use and abuse of this dangerous and ubiquitous substance.

This multi-author, multinational book has provided a source of information about the forensic aspects of medicine and related fields for those currently involved in the clinical and pathologic aspects of health care, forensic assessment, investigation and diagnosis for victims, assailants and others involved in police or judicial systems.

This book provides a comprehensive overview of the current state of knowledge concerning neuropathologies resulting from drug abuse. The first chapters offer readers detailed information on the neurobiological basics of drug abuse and the results of neuroimaging studies in drug abusers. The focus of the book is on neuropathological findings in drug abusers for the predominant substances, which include cannabis, opiates, cocaine, amphetamine, methamphetamine and a broad spectrum of designer drugs. These findings are supported by histological illustrations and discussed in connection with recent scientific publications. A chapter specifically addressing clinicians is also included, and highlights the implications for further therapy. The book is essential reading for neuropathologists, neurologists, neuroradiologists and psychiatrists, as well as other health professionals and scientists interested and engaged in the problem of drug abuse. Although a great deal of data has been derived from animal models and from human neuroimaging studies, little is known about the morphological effects of drug abuse on the human brain. In recent years, fundamental drug-induced effects on the cellular elements of the brain have been detected. These alterations might not only be the substrate of the neuroimaging data but might also have implications for clinical research and therapy. In addition, drug abuse may induce premature neurodegeneration.