John Hughes was born 10 January 1653 in Merionethshire, Wales. His parents were Hugh ap Cadwalader ap Rhys and Gwen Williams. He married Gwena Cadwalader in 1676. They had eight children. They emigrated in 1698 and settled in Berks County, Pennsylvania. He died in 1736. Ancestors, descendants and relatives lived mainly in Wales, Pennsylvania and Illinois.

Every 3rd issue is a quarterly cumulation.

Jason Penrose (1832-1922) was a descendant of Robert Penrose (b. 1673) and Mary Chaytor, who immigrated from Dublin, Ireland to Penn. in 1717. They had 10 children. Jason married Martha Harmer, descendant of Adam Rauenzahner/Routsong (b. 1764) and his wife, Catherine. Jason and Martha had four children, all born in Pennsville, Ohio.