Introduction to Statistics for the Life and Biomedical Sciences has been written to be used in conjunction with a set of self-paced learning labs. These labs guide students through learning how to apply statistical ideas and concepts discussed in the text with the R computing language.The text discusses the important ideas used to support an interpretation (such as the notion of a confidence interval), rather than the process of generating such material from data (such as computing a confidence interval for a particular subset of individuals in a study). This allows students whose main focus is understanding statistical concepts to not be distracted by the details of a particular software package. In our experience, however, we have found that many students enter a research setting after only a single course in statistics. These students benefit from a practical introduction to data analysis that incorporates the use of a statistical computing language.In a classroom setting, we have found it beneficial for students to start working through the labs after having been exposed to the corresponding material in the text, either from self-reading or through an instructor presenting the main ideas. The labs are organized by chapter, and each lab corresponds to a particular section or set of sections in the text.There are traditional exercises at the end of each chapter that do not require the use of computing. In the current posting, Chapters 1 - 5 have end-of-chapter exercises. More complicated methods, such as multiple regression, do not lend themselves to hand calculation and computing is necessary for gaining practical experience with these methods. The lab exercises for these later chapters become an increasingly important part of mastering the material.An essential component of the learning labs are the "Lab Notes" accompanying each chapter. The lab notes are a detailed reference guide to the R functions that appear in the labs, written to be accessible to a first-time user of a computing language. They provide more explanation than available in the R help documentation, with examples specific to what is demonstrated in the labs.

The OpenIntro project was founded in 2009 to improve the quality and availability of education by producing exceptional books and teaching tools that are free to use and easy to modify. We feature real data whenever possible, and files for the entire textbook are freely available at openintro.org. Visit our website, openintro.org. We provide free videos, statistical software labs, lecture slides, course management tools, and many other helpful resources.

An understanding of statistics and experimental design is essential for life science studies, but many students lack a mathematical background and some even dread taking an introductory statistics course. Using a refreshingly clear and encouraging reader-friendly approach, this book helps students understand how to choose, carry out, interpret and report the results of complex statistical analyses, critically evaluate the design of experiments and proceed to more advanced material. Taking a straightforward conceptual approach, it is specifically designed to foster understanding, demystify difficult concepts and encourage the unsure. Even complex topics are explained clearly, using a pictorial approach with a minimum of formulae and terminology. Examples of tests included throughout are kept simple by using small data sets. In addition, end-of-chapter exercises, new to this edition, allow self-testing. Handy diagnostic tables help students choose the right test for their work and remain a useful refresher tool for postgraduates.

This book provides an essential understanding of statistical concepts necessary for the analysis of genomic and proteomic data using computational techniques. The author presents both basic and advanced topics, focusing on those that are relevant to the computational analysis of large data sets in biology. Chapters begin with a description of a statistical concept and a current example from biomedical research, followed by more detailed presentation, discussion of limitations, and problems. The book starts with an introduction to probability and statistics for genome-wide data, and moves into topics such as clustering, classification, multi-dimensional visualization, experimental design, statistical resampling, and statistical network analysis. Clearly explains the use of bioinformatics tools in life sciences research without requiring an advanced background in math/statistics Enables biomedical and life sciences researchers to successfully evaluate the validity of their results and make inferences Enables statistical and quantitative researchers to rapidly learn novel statistical concepts and techniques appropriate for large biological data analysis Carefully revisits frequently used statistical approaches and highlights their limitations in large biological data analysis Offers programming examples and datasets Includes chapter problem sets, a glossary, a list of statistical notations, and appendices with references to background mathematical and technical material Features supplementary materials, including datasets, links, and a statistical package available online Statistical Bioinformatics is an ideal textbook for students in medicine, life sciences, and bioengineering, aimed at researchers who utilize computational tools for the analysis of genomic, proteomic, and many other emerging high-throughput molecular data. It may also serve as a rapid introduction to the bioinformatics science for statistical and computational students and audiences who have not experienced such analysis tasks before.

This book is written in a very easy-to-follow format, and explains the key concepts of biomedical statistics in a lucid yet straightforward manner. It explains how mathematical and statistical tools can be used to find answers to common research questions. In addition, the main text is supplemented by a wealth of solved exercises and illustrative examples to aid in comprehension. Given its content, the book offers an invaluable quick reference guide for graduating students and can be very helpful in their examination process. At the same time, it represents a handy guide for medical and paramedical teachers, post-graduate medical students, research personnel, biomedical scientists and epidemiologists.

Elementary rules of probability; Populations, samples, and the distribution of the sample mean; Analysis of matched pairs using sample means; Analysis of the two-sample location problem using sample means; Surveys and experiments in medical research; Statistical inference for dichotomous variables; Comparing two success probabilities; Chi-squared tests; Analysis of k-sample problems; Linear regression and correlation; Analysis of matched pairs using ranks; Analysis of the two-sample location problem using ranks; Methods for censored data.

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

"Learning Statistics with R" covers the contents of an introductory statistics class, as typically taught to undergraduate psychology students, focusing on the use of the R statistical software and adopting a light, conversational style throughout. The book discusses how to get started in R, and gives an introduction to data manipulation and writing scripts. From a statistical perspective, the book discusses descriptive statistics and graphing first, followed by chapters on probability theory, sampling and estimation, and null hypothesis testing. After introducing the theory, the book covers the analysis of contingency tables, t-tests, ANOVAs and regression. Bayesian statistics are covered at the end of the book. For more information (and the opportunity to check the book out before you buy!) visit http://ua.edu.au/ccs/teaching/lsr or http://learningstatisticswithr.com