Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.

Implantable Electronic Medical Devices provides a thorough review of the application of implantable devices, illustrating the techniques currently being used together with overviews of the latest commercially available medical devices. This book provides an overview of the design of medical devices and is a reference on existing medical devices. The book groups devices with similar functionality into distinct chapters, looking at the latest design ideas and techniques in each area, including retinal implants, glucose biosensors, cochlear implants, pacemakers, electrical stimulation therapy devices, and much more. Implantable Electronic Medical Devices equips the reader with essential background knowledge on the application of existing medical devices as well as providing an introduction to the latest techniques being used. - A catalogue of existing implantable electronic medical devices - Up-to-date information on the design of implantable electronic medical devices - Background information and reviews on the application and design of up-to-date implantable electronic medical devices

Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.

This book is a comprehensive, interdisciplinary resource for the latest information on implantable medical devices, and is intended for graduate students studying electrical engineering, electronic instrumentation, and biomedical engineering. It is also appropriate for academic researchers, professional engineers, practicing doctors, and paramedical staff. Divided into two sections on Basic Concepts and Principles, and Applications, the first section provides an all-embracing perspective of the electronics background necessary for this work. The second section deals with pacing techniques used for the heart, brain, spinal cord, and the network of nerves that interlink the brain and spinal cord with the major organs, including ear and eye prostheses. The four main offshoots of implantable electronics, which this book discusses, are: The insertion of an implantable neural amplifier for accurate recording of neural signals for neuroengineering studies The use of implantable pulse generators for pacing the activities of diseased organs The use of implantable sensors for observing the influence of therapy and monitoring a patient’s biological parameters The use of drug delivery systems to supervise the supply of accurate doses of medicine to affected parts Readers will also find chapters on the essentials of clocking and timing circuits, pulse generator circuits, neural amplifiers, batteries, biomaterials and biocompatibility, and more. Unique to this book is also a chapter on cyber security and confidentiality concerns with implants. End-of-chapter questions and exercises help readers apply the content to practical use, making this an ideal book for anyone wishing to learn more about implantable devices.

Research and innovation in areas such as circuits, microsystems, packaging, biocompatibility, miniaturization, power supplies, remote control, reliability, and lifespan are leading to a rapid increase in the range of devices and corresponding applications in the field of wearable and implantable biomedical microsystems, which are used for monitoring, diagnosing, and controlling the health conditions of the human body. This book provides comprehensive coverage of the fundamental design principles and validation for implantable microsystems, as well as several major application areas. Each component in an implantable device is described in details, and major case studies demonstrate how these systems can be optimized for specific design objectives. The case studies include applications of implantable neural signal processors, brain-machine interface (BMI) systems intended for both data recording and treatment, neural prosthesis, bladder pressure monitoring for treating urinary incontinence, implantable imaging devices for early detection and diagnosis of diseases as well as electrical conduction block of peripheral nerve for chronic pain management. Implantable Biomedical Microsystems is the first comprehensive coverage of bioimplantable system design providing an invaluable information source for researchers in Biomedical, Electrical, Computer, Systems, and Mechanical Engineering as well as engineers involved in design and development of wearable and implantable bioelectronic devices and, more generally, teams working on low-power microsystems and their corresponding wireless energy and data links. - First time comprehensive coverage of system-level and component-level design and engineering aspects for implantable microsystems. - Provides insight into a wide range of proven applications and application specific design trade-offs of bioimplantable systems, including several major case studies - Enables Engineers involved in development of implantable electronic systems to optimize applications for specific design objectives.

Wearable and Implantable Medical Devices: Applications and Challenges, Fourth Edition highlights the new aspects of wearable and implanted sensors technology in the healthcare sector and monitoring systems. The book's contributions include several interdisciplinary domains, such as wearable sensors, implanted sensors devices, Internet-of-Things (IoT), security, real-time medical healthcare monitoring, WIBSN design and data management, encryption, and decision-support systems. Contributions emphasize several topics, including real-world applications and the design and implementation of wearable devices. This book demonstrates that this new field has a brilliant future in applied healthcare research and in healthcare monitoring systems. - Includes comprehensive information on wearable and implanted device technology, wearable and implanted sensors design, WIBSN requirements, WIBSN in monitoring systems and security concepts - Highlights machine learning and computing in healthcare monitoring systems based on WIBSN - Includes a multidisciplinary approach to different healthcare applications and their associated challenges based on wearable and implanted technologies

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. - Provides useful information on the fundamentals of biofilm problems in medical devices - Discusses biofilm problems in a range of medical devices - Focuses on strategies for prevention of biofilm formation

A guide to the theory and recent development in the medical use of antenna technology Antenna and Sensor Technologies in Modern Medical Applications offers a comprehensive review of the theoretical background, design, and the latest developments in the application of antenna technology. Written by two experts in the field, the book presents the most recent research in the burgeoning field of wireless medical telemetry and sensing that covers both wearable and implantable antenna and sensor technologies. The authors review the integrated devices that include various types of sensors wired within a wearable garment that can be paired with external devices. The text covers important developments in sensor-integrated clothing that are synonymous with athletic apparel with built-in electronics. Information on implantable devices is also covered. The book explores technologies that utilize both inductive coupling and far field propagation. These include minimally invasive microwave ablation antennas, wireless targeted drug delivery, and much more. This important book: Covers recent developments in wireless medical telemetry Reviews the theory and design of in vitro/in vivo testing Explores emerging technologies in 2D and 3D printing of antenna/sensor fabrication Includes a chapter with an annotated list of the most comprehensive and important references in the field Written for students of engineering and antenna and sensor engineers, Antenna and Sensor Technologies in Modern Medical Applications is an essential guide to understanding human body interaction with antennas and sensors.

This book equips readers to understand a complex range of healthcare products that are used to diagnose, monitor, and treat diseases or medical conditions affecting humans. The first part of the book presents medical technologies such as medical information retrieval, tissue engineering techniques, 3D medical imaging, nanotechnology innovations in medicine, medical wireless sensor networks, and knowledge mining techniques in medicine. The second half of the book focuses on healthcare technologies including prediction hospital readmission risk, modeling e-health framework, personal Web in healthcare, security issues for medical records, and personalized services in healthcare. The contributors are leading world researchers who share their innovations, making this handbook the definitive resource on these topics. Handbook of Medical and Healthcare Technologies is intended for a wide audience including academicians, designers, developers, researchers and advanced-level students. It is also valuable for business managers, entrepreneurs, and investors within the medical and healthcare industries.

As we are increasingly using new technologies to change ourselves beyond therapy and in accordance with our own desires, understanding the challenges of human enhancement has become one of the most urgent topics of the current age. This volume contributes to such an understanding by critically examining the pros and cons of our growing ability to shape human nature through technological advancements. The authors undertake careful analyses of decisive questions that will confront society as enhancement interventions using bio-, info-, neuro- and nanotechnologies become widespread in the years to come. They provide the reader with the conceptual tools necessary to address such questions fruitfully. What makes the book especially attractive is the combination of conceptual, historical and ethical approaches, rendering it highly original. In addition, the well-balanced structure allows both favourable and critical views to be voiced. Moreover, the work has a crystal clear structure. As a consequence, the book is accessible to a broad academic audience. The issues raised are of interest to a wide reflective public concerned about science and ethics, as well as to students, academics and professionals in areas such as philosophy, applied ethics, bioethics, medicine and health management.