Immunotherapy Of Type 1 Diabetes
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Author |
: Domenico Andreani |
Publisher |
: John Wiley & Sons |
Total Pages |
: 280 |
Release |
: 1989 |
ISBN-10 |
: UOM:39015015329371 |
ISBN-13 |
: |
Rating |
: 4/5 (71 Downloads) |
Synopsis Immunotherapy of Type 1 Diabetes by : Domenico Andreani
Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.
Author |
: Khawaja Husnain Haider |
Publisher |
: Walter de Gruyter GmbH & Co KG |
Total Pages |
: 309 |
Release |
: 2018-12-17 |
ISBN-10 |
: 9783110586916 |
ISBN-13 |
: 3110586916 |
Rating |
: 4/5 (16 Downloads) |
Synopsis Stem Cells – From Hype to Real Hope by : Khawaja Husnain Haider
This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.
Author |
: Terry B. Strom |
Publisher |
: Wiley-Blackwell |
Total Pages |
: 672 |
Release |
: 2001-03-30 |
ISBN-10 |
: 0632043598 |
ISBN-13 |
: 9780632043590 |
Rating |
: 4/5 (98 Downloads) |
Synopsis Therapeutic Immunology by : Terry B. Strom
Therapeutic Immunology is a comprehensive review of the clinical application of the drugs, biologic agents, and procedures used to treat immunologic diseases. It is the only reference that provides current information on antibodies, cytokines, gene and cell therapies, vaccines, and other therapeutic approaches in the managament of immune system disorders. This book will show how immunology has come of age as a clinical discipline and is now able to provide treatment strategies for many previously incurable diseases.
Author |
: Mark A. Sperling |
Publisher |
: |
Total Pages |
: 0 |
Release |
: 2005 |
ISBN-10 |
: 141602753X |
ISBN-13 |
: 9781416027539 |
Rating |
: 4/5 (3X Downloads) |
Synopsis Diabetes Mellitus in Children by : Mark A. Sperling
Author |
: Mourad Aribi |
Publisher |
: BoD – Books on Demand |
Total Pages |
: 184 |
Release |
: 2017-03-22 |
ISBN-10 |
: 9789535130215 |
ISBN-13 |
: 9535130218 |
Rating |
: 4/5 (15 Downloads) |
Synopsis Immunopathogenesis and Immune-based Therapy for Selected Autoimmune Disorders by : Mourad Aribi
The book Immunopathogenesis and Immune-Based Therapy for Selected Autoimmune Disorders is a synthesis work that discusses two main aspects of autoimmunity: Immunopathogenesis and therapeutic approaches essentially based on the immunotherapies. This book deals with different topics on a number of autoimmune disorders, including type 1 diabetes, autoimmune cardiomyopathy, autoimmunity of gastrointestinal tract, systemic sclerosis, and myasthenia gravis. This book will be useful to clinicians, biologists, researchers, teachers, and students who are interested in immunology and immunopathology.
Author |
: B. Kyewski |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 331 |
Release |
: 2006-01-09 |
ISBN-10 |
: 9783540277026 |
ISBN-13 |
: 3540277021 |
Rating |
: 4/5 (26 Downloads) |
Synopsis CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential by : B. Kyewski
The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-reactive T cells via negative selection in the thymus dominant tolerance exerted by regulatory T cells plays a major role in tolerance imposition and maintenance. Among the various regulatory/suppressive cells hitherto described, CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues. The repertoire of Treg is clearly biased towards recognition of self-antigens, thereby potentially preventing autoimmune diseases such as gastritis and oophoritis. Regulatory T cells, however also control infections, allergies and tolerance to transplanted tissues and this requires their induction in the periphery under conditions which are not yet fully understood. The concept of dominant tolerance, by far not novel, will offer new insights and hopefully tools for the successful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival. The fulfillment of these high expectations will, however, require their unambiguous identification and a better understanding of their mode of action.
Author |
: F. Bandello |
Publisher |
: Karger Medical and Scientific Publishers |
Total Pages |
: 206 |
Release |
: 2017-04-20 |
ISBN-10 |
: 9783318060423 |
ISBN-13 |
: 3318060429 |
Rating |
: 4/5 (23 Downloads) |
Synopsis Management of Diabetic Retinopathy by : F. Bandello
Recently developed diagnostic and therapeutic technologies such as OCT-angiography and small gauge vitrectomy have influenced the modern treatment of diabetic retinopathy. This volume provides a summary of the state-of-the-art evidence-based approach to managing complications that may occur with diabetic retinopathy. It offers the latest information on pathogenesis and diagnosis, and highly experienced clinicians review the results of relevant randomized clinical trials that serve as the basis of current therapy. The book provides not only a summary of data from randomized trials but also an analysis and interpretation by internationally renowned experts. Ophthalmology residents, fellows, and practicing clinicians will find this book to be a useful reference when seeking evidence-based treatment strategies for various complications of diabetic retinopathy. It is also for researchers identifying new avenues of drug developments and for insurance professionals and health care policy administrators who are establishing evidence-based therapy guidelines for therapeutic intervention.
Author |
: Jay Skyler |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 424 |
Release |
: 2012-03-08 |
ISBN-10 |
: 9781461410287 |
ISBN-13 |
: 1461410282 |
Rating |
: 4/5 (87 Downloads) |
Synopsis Atlas of Diabetes by : Jay Skyler
This handbook is an invaluable resource for improving the management of diabetes. Chapters cover the fundamentals, including epidemiology, history and physical examination, and functional evaluations. Diabetes in children, adolescents, adults, and geriatrics are addressed. Differential diagnosis is emphasized, and evidence-based guidelines and patient-specific considerations aid the reader with injury evaluation and care. Notably, the book highlights the importance of understanding diabetic symptoms when determining the source of illnesses. In addition, the text presents the spectrum of treatment options for diabetes. The book is complete with appendices that explain the evidence-based approach used throughout and the science behind therapeutic modalities.
Author |
: Emmanuel C. Opara |
Publisher |
: CRC Press |
Total Pages |
: 412 |
Release |
: 2019-01-03 |
ISBN-10 |
: 9781351780094 |
ISBN-13 |
: 1351780093 |
Rating |
: 4/5 (94 Downloads) |
Synopsis Nutrition and Diabetes by : Emmanuel C. Opara
Diabetes occurs at such an alarming rate that it can be described as a global epidemic. Following its predecessor, Nutrition and Diabetes: Pathophysiology and Management, Second Edition, is a comprehensive resource that describes various factors that drive the accumulation of excess body weight and fat resulting in obesity. The book discusses the metabolic aberrations found in obesity and how they lead to the association of obesity with diabetes. This new edition highlights the role played by diet and the interrelationships in the metabolism of key nutrients in the pathogenesis of obesity and diabetes which provides the scientific basis for treatment and management approaches. Features Highlights the role of nutrition in the pathogenesis of obesity and diabetes Organized logically into two easy-to-use sections - Pathophysiology and Management of Obesity and Pathophysiology and Treatment of Diabetes Features emerging therapeutic approaches for management of obesity and diabetes Discusses experience in the management of obesity and diabetes in developing countries Presents challenges in insulin therapy and provides guidelines to overcome them The first section of the book retains key topics from the previous edition and contains new chapters including genetic determinants of nutrient processing; fat distribution and diabetes mellitus; combined effect of diet and physical activity in the management of obesity; pharmacologic treatment of obesity; and the role of gut microbiota in the pathogenesis and treatment of obesity. The second section features updated versions of most of the other chapters in the first edition comprising a modified chapter on oxidative stress and the effects of dietary supplements on glycemic control in Type 2 diabetes. In addition, new chapters are added in this section and include the contribution of iron and transition metal micronutrients to diabetes; role of microbiota in the pathogenesis and treatment of diabetes; primary prevention of Type 2 diabetes; and the pathophysiology and management of Type 1 diabetes.
Author |
: A. M. James Shapiro |
Publisher |
: CRC Press |
Total Pages |
: 0 |
Release |
: 2007-07-25 |
ISBN-10 |
: 0824728629 |
ISBN-13 |
: 9780824728625 |
Rating |
: 4/5 (29 Downloads) |
Synopsis Islet Transplantation and Beta Cell Replacement Therapy by : A. M. James Shapiro
Beta cell replacement through transplantation remains the only treatment option for Type 1 diabetes enabling restoration of near-physiological glucose levels without significant hypoglycemia. Outlining the most recent advances and research breakthroughs, this practical guide and reference work explores the impact of islet cell transplantation and brings together leading multidisciplinary proponents critical to future success in the field. Edited by a surgeon and an endocrinologist at the forefront of the technology, this volume considers challenges associated with this procedure including lack of sufficient donor organs and the side effects of immunosuppressive therapy, as well as the potential benefits for current and future patients. Islet Transplantation and Beta Cell Replacement Therapy, after a brief historical overview, examines: the key role of endocrinologists in holistic assessment and selection of islet transplant recipients the factors underlying attrition of islet function over time and need for enhanced graft monitoring post transplantation future in vivo islet imaging setting up new clinical islet transplant programs by outlining potential models and pitfalls-including cost effectiveness and sustainable integrated approaches clinical outcomes and the future direction for islet transplantation, including alternative sources of beta cells, to meet future clinical needs through xenotransplantation, new insulin-producing cells from adult tissue, and stem cell banks