Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. - Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition - Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline - Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline - Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering - New chapters on genetics, evolutionary biology, bone aging, and epigenetic control - Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.

The Handbook of the Psychology of Aging, Seventh Edition, provides a basic reference source on the behavioral processes of aging for researchers, graduate students, and professionals. It also provides perspectives on the behavioral science of aging for researchers and professionals from other disciplines. The book is organized into four parts. Part 1 reviews key methodological and analytical issues in aging research. It examines some of the major historical influences that might provide explanatory mechanisms for a better understanding of cohort and period differences in psychological aging processes. Part 2 includes chapters that discuss the basics and nuances of executive function; the history of the morphometric research on normal brain aging; and the neural changes that occur in the brain with aging. Part 3 deals with the social and health aspects of aging. It covers the beliefs that individuals have about how much they can control various outcomes in their life; the impact of stress on health and aging; and the interrelationships between health disparities, social class, and aging. Part 4 discusses the emotional aspects of aging; family caregiving; and mental disorders and legal capacities in older adults. - Contains all the main areas of psychological gerontological research in one volume - Entire section on neuroscience and aging - Begins with a section on theory and methods - Edited by one of the father of gerontology (Schaie) and contributors represent top scholars in gerontology

Handbook of Aging and the Social Sciences, Seventh Edition, provides extensive reviews and critical evaluations of research on the social aspects of aging. It also makes available major references and identifies high-priority topics for future research. The book is organized into four parts. Part 1 reviews developments in the field of age and the life course (ALC) studies and presents guidelines on conducting cohort analysis. Part 2 covers the demographic aspects of aging; longevity trends; disability and aging; and stratification and inequality research. Part 3 includes chapters that examine socioeconomic position and racial/ethnic disparities in health at older ages; the role of social factors in the distribution, antecedents, and consequences of depression; and aspects of private wealth transfers and the changing nature of family gift-giving. Part 4 deals with pension reform in Europe; the political activities of older Americans; the future of retirement security; and gender differences in old age. The Handbook is intended for researchers, professional practitioners, and students in the field of aging. It can also serve as a basic reference tool for scholars, professionals, and others who are not presently engaged in research and practice directly focused on aging and the aged. - Contains all the main areas of social science gerontological research in one volume - Begins with a section on theory and methods - Edited by one of the fathers of gerontology (Binstock) and contributors represent top scholars in gerontology

The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. - Combines both the methods of study for human aging and animal models - Provides a historical overview and discussion of model availability, key methods and ethical issues - Contains over 200 full color illustrations

Robert Arking's Biology of Aging is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging.

Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.

The field of gerontology has often been criticized for being "data-rich but theory-poor." The editors of this book address this issue by stressing the importance of theory in gerontology. While the previous edition focused on multidisciplinary approaches to aging theory, this new edition provides cross-disciplinary, integrative explanations of aging theory: The contributors of this text have reached beyond traditional disciplinary boundaries to partner with researchers in adjacent fields in studying aging and age-related phenomena. This edition of the Handbook consists of 39 chapters written by 67 internationally recognized experts in the field of aging. It is organized in seven sections, reflecting the major theoretical developments in gerontology over the past 10 years. Special Features: Comprehensive coverage of aging theory, focusing on the biological, psychological, and social aspects of aging A section dedicated to discussing how aging theory informs public policy A concluding chapter summarizing the major themes of aging, and offering predictions about the future of theory development Required reading for graduate students and post doctoral fellows, this textbook represents the current status of theoretical development in the study of aging.

This book is a thorough revision of one of the most comprehensive reference volumes for persons working in the area of aging and mental health. The thrust of the work is interdisciplinary, and discusses research on both clinical and practical issues in aging and mental health.The multidisciplinary nature of this book and the inclusion of subject matter from the professional as well as research realm result in a level of comprehensiveness which is distinct in the field of mental health and agingEach chapter contains a comprehensive bibliography, the compilation of which represents a definitive reference source in the fieldThe chapters review state-of-the-art research in the biological, behavioral, and social sciences and represent the cutting-edge of current practice in psychiatry, neurology, social work, nursing, psychology, and pharmacology, among other professionsThe compilation of prevalence data is a much-needed addition to the current literatureThe multidisciplinary nature of this book and the inclusion of both clinical and practical issues makes the book distinctively comprehensive