Handbook of Mediators in Septic Shock presents a comprehensive, systematic evaluation of the various putative mediators of septic shock through the use of meta-analysis. Experts of individual mediators have objectively evaluated the collective literature using classical Koch-Dale Criteria for causal relationships. A decision tree approach has been used to analyze the existing evidence for each of the four Koch-Dale Criteria for each individual mediator of septic shock. The book provides an integrated perspective that describes how these many mediators interact. It also covers how advances in mathematical modeling of complex realities are applied to the field of septic shock pathogenesis. CRC Handbook of Mediators in Septic Shock will be a useful reference for emergency room and intensive care physicians, trauma specialists, pathophysiologists, physiologists, biochemists, pharmacologists, and others interested in the topic. Features

This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of shock – septic, hemorrhagic, cardiogenic, anaphylactic, and obstructive – at all stages from initial response through to ICU admission. As well as management, the coverage encompasses pathophysiology, clinical presentation, diagnosis, and emerging trends. A further key feature is the use of a scenario-based approach to present a series of cases based on real-life experiences. Here, a narrative style and Q&A form are employed to vividly convey scenarios that may be encountered in clinical practice and to elucidate decision making in complex circumstances. When readers experience difficulty in answering the questions, the earlier sections can be consulted to identify the correct response. This book will be of great value for all health care professionals. In particular, it will be very helpful for novice or inexperienced practitioners in emergency medicine, critical care medicine, and traumatology.

Handbook of ICU Therapy provides rapid access to important information on the treatment of the critically ill patient. It comprises a series of 'cutting edge' reviews of the most advanced treatment concepts available in the modern ICU. Whilst assuming a basic knowledge of underlying conditions, it nonetheless outlines key physiological principles where necessary, and critically reviews current literature and best practice. The heart of the book is aimed at providing key practical information on treatment techniques to the busy clinician in an easily accessible style. In addition to conventional drug therapy, ventilator, fluid and physical therapies are also discussed in detail. All of the authors are directly involved in ICU research and practice and are familiar with all of the latest developments in this fast-moving field of medicine.

Focused on the practical issues of nursing care and nursing procedures, the Oxford Handbook of Critical Care Nursing has been written by nurses, for nurses Reflecting current best practice, this handbook is an easily accessible and evidence-based guide for all levels of nursing staff working in critical care environments. It provides the nurse at the bedside with the answers to day-to-day problems experienced when caring for critically ill patients, and is also a guide to some of the less commonly encountered issues. Now including more detail on the psychological issues facing critically ill patients and further information on the intricacies of receiving and transferring critically ill patients to and from critical care environments, this handbook is a concise, practical, evidence-based guide for nursing professionals caring for critically ill patients

First multi-year cumulation covers six years: 1965-70.

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Everything you need to pass the NAPLEX® – comprehensive study material and two practice exams – in one student-reviewed package Written by an instructor who has taught thousand of students, this all-in-one study guide was developed and reviewed by pharmacists, faculty, students, and recent graduates – so you know it contains only the most relevant, up-to-date conent. You’ll find valuable foundational material and chapter-ending case application questions that cover every key topic included on the NAPLEX. Two downloadable practice tests with a total of 370 questions allowing you to pinpoint your weaknesses. Includes: Coverage that is organized around the NABP competencies and designed to sharpen problem-solving skills, put must-know information at your fingertips, and improve exam-taking ability More than 1400 case application questions, each with a detailed explanation of both correct and incorrect answer choices Takeaway Points at the end of every chapter that summarize key concepts Two complete downloadable practice tests, each with 185 questions

"The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals" is an indispensable resource for physicians, nurse practitioners, physician assistants, pharmacists, and nurses in managing critically ill patients. This comprehensive guide delves deep into the world of vasopressors and inotropes, offering a blend of scientific understanding using evidence-based medicine and practical wisdom. Authored by Dr. Eddy J Gutierrez, a board-certified Intensivist, this handbook begins with the basic pillars of hemodynamics. It then progresses beyond basic concepts to detailed discussions on each type of vasopressor and inotrope, providing insights into their clinical applications, indications, and contraindications using evidence-based practices as the foundation. Its unique question-and-answer format demystifies topics like shock management, cardiac output improvement, and patient stabilization, making it ideal for students and healthcare professionals. Real-world case studies and clinical scenarios enrich the text, offering practical examples of how to apply theoretical knowledge in a clinical setting. The book emphasizes the importance of personalized medicine, advocating for tailored treatment plans and continuous patient monitoring to ensure the best possible outcomes. Whether you're a seasoned critical care professional or new to the field, "The Vasopressor & Inotrope Handbook" is a valuable addition to your library. It not only serves as a day-to-day reference but also as a foundation for ongoing learning in this dynamic and challenging area of medicine. Elevate your medical expertise today. Click to purchase "The Vasopressor & Inotrope Handbook" and become adept at navigating the complexities of vasopressors and inotropes in clinical practice!

A unique reference manual for academic surgeons, this book discusses every facet of surgical research. From getting grant money to choosing a topic, reviewing the literature, planning and conducting research, and reporting results.