This issue of Critical Care Clinics focuses on Gastrointestinal Critical Care. Articles include: Non variceal Upper Gastrointestinal bleeds; Lower Gastrointestinal bleeds; Mesenteric Ischemia; Peritonitis; The open abdomen and intra abdominal infections; Gut motility issues in critical illness; Gut as the motor of multiple organ dysfunction; Intra abdominal hypertension and abdominal compartment syndrome; Abdominal circulatory interactions in critical illness; Severe acute pancreatitis and necrotizing pancreatitis; and Nutrition in the critically ill.

This issue of Critical Care Clinics focuses on Hepatology and Critical Care. Articles include: Acute on Chronic and Decompensated Chronic Liver Failure, Hepatic Encephalopathy, Respiratory Complication in Liver Disease, GI Issues in Liver Disease, Bridging the Patient with Liver Disease to Transplant or Recovery, Infections in Liver Disease, Kidney Injury in Liver Disease, The Liver in Critical Illness, Hematological Issues in Liver Disease, Pharmacological Issues in Liver Disease and more!

This issue of Critical Care Clinics focuses on Obstetric and Gynecologic Emergencies in the ICU. Articles include: Respiratory Failure and Mechanical Ventilation in the Pregnant Patient, Anesthetic Complications in Pregnancy, Neurologic Complications in Pregnancy, Renal Failure in Pregnancy, Management Complex Cardiac Issues in the Pregnant Patient, Liver Failure in Pregnancy, Hypertensive Emergencies in Pregnancy, Ethical Issues in Pregnancy, and more!

Dr. John Kellum has assembled an essential update on the topic of Nephrology as it relates to Critical Care Medicine. Articles include: Diagnostic criteria, Biomarkers for AKI, Sepsis-induced AKI,Drug-induced AKI, Cardio-renal syndrome,Surgery Associated AKI,Contrast-induced AKI, Principles of Fluid Therapy,Fluid composition and clinical effects, Renal replacement therapy, and Understanding acid-base.

Gastrointestinal dysfunction or injury is common in the critical care patient either as a primary diagnosis or as secondary symptoms. Several studies confirm that up to 62% of critical care patients exhibit at least one GI symptom for at least one day. In addition, recent studies have shown that GI problems are related to negative outcomes in the critical care patient. The articles in this issue are current and relevant to critical care patients today: Autoimmune Disease of the Gut in the Critical Care Patient; Nutrition Options in CCU Patients; Mesenteric Ischemia; Management of C-Diff in Critical Care Setting; Management of Acute GI Bleed; Acute Diverticulitis Management; GI Patient Skills Training in the ICU: SOFA assessment and recognizing GI symptoms; EBP with probiotics in treatment for antibiotic associated diarrhea in the ICU; GI Problems in the ICU with Patients with HIV/AIDs; Complications of GI Motility/GI Failure in the Critically Ill Patient; Untreated Gastroesophageal Reflux Patients in the ICU; Liver Transplant; Ecoli Complications in Critical Care-Pediatrics; and GI Traumatic injuries: GI Perforation. Being knowledgeable and skillful in the recognition and care for these problems is paramount to the critical care nurse.

This issue of Critical Care Clinics focuses on Burn Resuscitation in the ICU. Articles include: The Physiologic Basis of Burn Shock and the Need for Aggressive Fluid Resuscitation; The Use of Colloid in Burn Resuscitation; Monitoring and Endpoints of Burn Resuscitation; Vitamin C in Burn Resuscitation; Pediatric Burn Resuscitation; Burn resuscitation in the Austere Environment; Failed Burn resuscitation; and more!

Guest editor Lena Napolitano has assembled an expert team of authors on the topic of Trauma in the ICU. Articles will focus on: Non-compressible Torso Hemorrhage; Prediction of Massive Transfusion in Trauma; Coagulopathy of Trauma; Viscoelastic testing and Hyperfibrinolysis in Trauma; Tranexamic Update in Trauma; Optimal Reversal of Novel Anticoagulants in Trauma; Optimal Transfusion for Traumatic Hemorrhagic Shock; and more

This issue provideds a comprehensive update to Sleep Medicine in the Intensive Care Unit, with editor Vipin Malik assembling a line-up of key topics such as:Sleep Neurobiology and Critical Care Illness,Obesity Hypoventilation Syndrome and Respiratory Failure,Obstructive Sleep Apnea,Non-Invasive Ventilation in Critically Ill Patients,Restless Leg Syndrome,Sleep and Endocrine System,Congestive Heart Failure and Central Sleep Apnea,Circadian Dysrhythmias,Neuromuscular Disorders and Sleep in Critically Ill Patients, Perioperative Issues and Sleep Disordered Breathing, Seizures, and more!

The second in a two-part series on Life-Threatening Infections. Article topics include: Biowarfare/Bioterrorism pathogens, Infections in neutropenics, Infections in AIDS, Influenza and endemic viral pneumonias, Resistant gram negative infections, Toxic Shock Syndrome, Fulminant viral myocarditis, and Overwhelming post-splenectomy infection.

The Guest Editors have assembled expert authors to contribute current reviews devoted to critical care in pediatrics. The articles are devoted to Simulation and Impact on Code Sepsis; Cardiac Rapid Response Team/Modified Cardiac PEWS Development; Impact on Cardiopulmonary Arrest Events on Inpatient Cardiac Unit; Promoting Safety in Post-Tracheostomy Placement Patients in the Pediatric Intensive Care Unit Through Protocol; Innovation in Hospital-Acquired Pressure Ulcers Prevention in Neonatal Post-Cardiac Surgery Patients; Utilizing an Interactive Patient Care System in an Acute Care Pediatric Hospital Setting to Improve Patient Outcomes; Advances in Pediatric Pulmonary Artery Hypertension; and Creating a Safety Program in a Pediatric Intensive Care Unit or Assessing Pain in the Pediatric Intensive Care Patients to name a few. Readers will come away with information that is actionable in the pediatric ICU.