A comprehensive overview of the principles and applications of femtosecond lasers, especially applied to medicine and to production technology. The advantages and problems of ultrashort laser pulses are discussed in more detail in the context of applications in the micro-machining of technical materials such as drilling, surface structuring and cutting, in medical use like dental, ophthalmologic, neurological and otolaryngological applications, in metrology, and in the generation of x-rays. Safety aspects are also considered.

There is no doubt that the advent of immunocytochemical techniques, by enhancing our ability to detect specific cell products or markers, has opened new avenues in the understanding of human diseases, and in our ability to perform better diagnosis in surgical pathology. The rapid development of this field has resulted in thousands of publications in the literature regarding immunocytochemistry in diagnostic pathology. This explosion of knowledge makes necessary publications summarizing what are the main markers available and how they can be used in the diagnosis of tumors. The need of a more organized and structured knowledge was evident during the workshop in Immunocytochemistry of Tumor Diagnosis that took place in the City of Detroit an October 1984. This book is the result of that workshop in which 22 chapters are focusing an the main subject of differential diagnosis of tumors. Jose Russo, M.D. Editor xiii ACKNOWLEDGEMENTS I wish to thank my many associates at the Michigan Cancer Foundation for their help in the preparation of this manuscript. I give thanks to Dr.

A comprehensive overview of the principles and applications of femtosecond lasers, especially applied to medicine and to production technology. The advantages and problems of ultrashort laser pulses are discussed in more detail in the context of applications in the micro-machining of technical materials such as drilling, surface structuring and cutting, in medical use like dental, ophthalmologic, neurological and otolaryngological applications, in metrology, and in the generation of x-rays. Safety aspects are also considered.

The book Femtosecond Laser: Techniques and Technology provides complete insight of Femtosecond Laser technology in various ocular indications. Refractive Surgery technology has undergone rapid advancements and innovations in last two decades. Femtosecond Laser offers new possibilities in the field of minimally invasive corneal surgery. It employs near infrared pulses to cut tissue with minimal collateral tissue damage. The highly localized tissue effect of low energy Femtosecond Laser shall expand the capabilities and precision of this technology in near future and may be used to create three-dimensional intrastromal resection with micron precision. Femtosecond laser is a simple, rapid reliable and efficient method in ophthalmology with satisfactory results for effective lens position and refractive outcome. Femtosecond laser is enjoying rapid growth in the area of cataract surgery. The Femtosecond Laser has proved its versatility in Lamellar keratoplasty, customized trephination in penetrating keratoplasty, tunnel creation for intracorneal ring segments, astigmatic keratotomy for keratoprostheses, non-invasive trans-scleral glaucoma surgery, retinal imaging presbyopic surgery and cataract surgery. Advances in ultrafast laser technology continued to improve the surgical safety, efficiency, speed and versatility of Femtosecond Lasers in Ophthalmology. Femtosecond Laser finds application in anterior and posterior segment indications of ophthalmology.

Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a new, comprehensive text that presents a practical approach to optimizing laser settings and procedure techniques for performing LASIK, intracorneal ring segment placement, and other corneal procedures with currently available femtosecond lasers. Dr. Ella Faktorovich has provided detailed photographs and illustrations to demonstrate the techniques for optimizing procedure outcomes. The author guides you step-by-step through common procedures while providing a detailed approach to managing and preventing possible complications. Topics covered include: - Strategies for centration - Decreasing the incidence of opaque bubble layer formation - Optimizing the energy delivered to the cornea - Improving the quality of dissection As the first book on femtosecond laser application to corneal surgery, Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a useful guide for beginning surgeons as well as surgeons looking to develop or enhance their working knowledge of femtosecond lasers.

Covering key techniques for optical microscopy and micro-fabrication, this book provides the first detailed treatment of femtosecond laser-based biophotonics. After a review of the techniques for nonlinear and multiphoton imaging, applications for laser-based manipulation of micro-particles are introduced. The final chapter focuses on the burgeoning field of femtosecond micro-engineering.

Ultrashort Laser Pulse Phenomena, Second Edition serves as an introduction to the phenomena of ultra short laser pulses and describes how this technology can be used to examine problems in areas such as electromagnetism, optics, and quantum mechanics. Ultrashort Laser Pulse Phenomena combines theoretical backgrounds and experimental techniques and will serve as a manual on designing and constructing femtosecond ("faster than electronics") systems or experiments from scratch. Beyond the simple optical system, the various sources of ultrashort pulses are presented, again with emphasis on the basic concepts and how they apply to the design of particular sources (dye lasers, solid state lasers, semiconductor lasers, fiber lasers, and sources based on frequency conversion). - Provides an easy to follow guide through "faster than electronics" probing and detection methods - THE manual on designing and constructing femtosecond systems and experiments - Discusses essential technology for applications in micro-machining, femtochemistry, and medical imaging

Ideal for cell biologists, life scientists, biomedical engineers, and clinicians, this handbook provides comprehensive treatment of the theories, techniques, and biomedical applications of nonlinear optics and microscopy.

Keeping abreast of the latest techniques and applications, this new edition of the standard reference and graduate text on laser spectroscopy has been completely revised and expanded. While the general concept is unchanged, the new edition features a broad array of new material. This new edition has been completely revised, especially the chapters on non linear spectroscopy, ion trapping, ultra short laser pulses and new developments. Fifty new figures illustrate the newest developments and results. The author is one of the most renowned experts in this area and no other book with this broad scope is available.

This book covers the fundamental principles and physical phenomena behind laser-based fabrication and machining processes. It also gives an overview of their existing and potential applications. With laser machining an emerging area in various applications ranging from bulk machining in metal forming to micromachining and microstructuring, this book provides a link between advanced materials and advanced manufacturing techniques. The interdisciplinary approach of this text will help prepare students and researchers for the next generation of manufacturing.