This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.

This volume presents the proceedings of a muscle symposium, which was held as the Fourth Fujihara seminar on October 28 - November 1, 2002, at Hakone, Japan. This volume covers all fields of muscle biology, from molecules to humans. This book provides information about recent progress of muscle research as well as the problems that remain to be investigated. This volume will stimulate muscle investigators to design and perform novel experiments to clarify the mysteries in muscle contraction.

This book represents the final reports of the scientific projects funded within the DFG-SPP1466 and, hence, provides the reader with the possibility to familiarize with the leading edge of VHCF research. It draws a balance on the existing knowledge and its enhancement by the joint research action of the priority program. Three different material classes are dealt with: structural metallic materials, long-fiber-reinforced polymers and materials used in micro-electro-mechanical systems. The project topics address the development of suitable experimental techniques for high-frequency testing and damage monitoring, the characterization of damage mechanisms and damage evolution, the development of mechanism-based models and the transfer of the obtained knowledge and understanding into engineering regulations and applications.

Fatigue is an important concern for all athletes, sportspeople and coaches, and in clinical exercise science. There remains considerable debate about the definition of fatigue, what causes it, what its impact is during different forms of exercise, and what the best methods are to combat fatigue and improve performance. This is the first student-focused book to survey the contemporary research evidence into exercise-induced fatigue and to discuss how knowledge of fatigue can be applied in sport and exercise contexts. The book examines the different ‘types’ of fatigue and the difficulties of identifying which types are prevalent during different types of exercise, including a discussion of the most important methods for measuring fatigue. It introduces the fundamental science of fatigue, focussing predominantly on covering physiological aspects, and explores key topics in detail, such as energy depletion, lactic acid, dehydration, electrolytes and minerals, and the perception of fatigue. Every chapter includes real case studies from sport and exercise, as well as useful features to aid learning and understanding, such as definitions of key terms, guides to further reading, discussion questions, and principles for training and applied practice. Fatigue in Sport and Exercise is an invaluable companion for any degree-level course in sport and exercise physiology, fitness and training, or strength and conditioning.

Fatigue of structures and materials covers a wide scope of different topics. The purpose of the present book is to explain these topics, to indicate how they can be analyzed, and how this can contribute to the designing of fatigue resistant structures and to prevent structural fatigue problems in service. Chapter 1 gives a general survey of the topic with brief comments on the signi?cance of the aspects involved. This serves as a kind of a program for the following chapters. The central issues in this book are predictions of fatigue properties and designing against fatigue. These objectives cannot be realized without a physical and mechanical understanding of all relevant conditions. In Chapter 2 the book starts with basic concepts of what happens in the material of a structure under cyclic loads. It illustrates the large number of variables which can affect fatigue properties and it provides the essential background knowledge for subsequent chapters. Different subjects are presented in the following main parts: • Basic chapters on fatigue properties and predictions (Chapters 2–8) • Load spectra and fatigue under variable-amplitude loading (Chapters 9–11) • Fatigue tests and scatter (Chapters 12 and 13) • Special fatigue conditions (Chapters 14–17) • Fatigue of joints and structures (Chapters 18–20) • Fiber-metal laminates (Chapter 21) Each chapter presents a discussion of a speci?c subject.

Written by a leading researcher in the field, this revised and updated second edition of a highly successful book provides an authoritative, comprehensive and unified treatment of the mechanics and micromechanisms of fatigue in metals, non-metals and composites. The author discusses the principles of cyclic deformation, crack initiation and crack growth by fatigue, covering both microscopic and continuum aspects. The book begins with discussions of cyclic deformation and fatigue crack initiation in monocrystalline and polycrystalline ductile alloys as well as in brittle and semi-/non-crystalline solids. Total life and damage-tolerant approaches are then introduced in metals, non-metals and composites followed by more advanced topics. The book includes an extensive bibliography and a problem set for each chapter, together with worked-out example problems and case studies. This will be an important reference for anyone studying fracture and fatigue in materials science and engineering, mechanical, civil, nuclear and aerospace engineering, and biomechanics.

Fatigue can have a major impact on an individual's performance and well-being, yet is poorly understood, even within the scientific community. There is no developed theory of its origins or functions, and different types of fatigue (mental, physical, sleepiness) are routinely confused. The widespread interpretation of fatigue as a negative consequence of work may be true only for externally imposed goals; meaningful or self-initiated work is rarely tiring and often invigorating. In the first book dedicated to the systematic treatment of fatigue for over sixty years, Robert Hockey examines its many aspects - social history, neuroscience, energetics, exercise physiology, sleep and clinical implications - and develops a new motivational control theory, in which fatigue is treated as an emotion having a fundamental adaptive role in the management of goals. He then uses this new perspective to explore the role of fatigue in relation to individual motivation, working life and well-being.