Complementary and Alternative Medicine is a sociological investigation of complementary and alternative medicine (CAM) in contemporary society, and an exploration of the forces throughout the globe, across different institutions, and within different therapeutic spaces, that constrain or foster alternative medicine. Drawing on 30 years of research, the book identifies the trends in the use of CAM and explores the scientific, political and social challenges that CAM faces in relation to orthodox medicine. The author examines the varieties of CAM practices and how they manifest in different institutional spaces – including public inquiries, the orthodox medical practitioner’s consulting room, medical journals and the homes of those who use CAM. It also compares unorthodox practices in different geo-political settings, namely the global north and the global south. This book is valuable reading for higher-level undergraduate and postgraduate social science students, including those in psychology, sociology, anthropology, health sciences and related disciplines. It is relevant for courses in medical sociology, medical anthropology and social science and health, and a broader audience interested in contemporary health issues, controversies and alternative medicine.

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

The revised edition of this award-winning book offers thirty-three Neuro Updates, which provide evidence-based data to help you recognize and explain the deeply transformational nature of the work. Expanding the Practice of Sex Therapy looks beyond behavioral treatments, pharmaceutical interventions, and performance goals to a comprehensive picture of what your clients want and need when they enter sex therapy, and offers creative ways to engage your clients in their own therapeutic process, whether or not you are trained as a sex therapist. Central to Gina Ogden’s approach is her Four-Dimensional Wheel of Sexual Experience, an innovative template that recognizes the full range of sexual issues: physical, emotional, mental, and spiritual. The text is organized into five practice-oriented sections that introduce the 4-D Wheel; show you how you can use it with individuals, couples, and groups; and encourage you to explore it on your own.

At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

All losses are touched with ambiguity. Yet those who suffer losses without finality bear a particular burden. Pauline Boss, the principal theorist of the concept of ambiguous loss, guides clinicians in the task of building resilience in clients who face the trauma of loss without resolution. Boss describes a concrete therapeutic approach that is at once directive and open to the complex contexts in which people find meaning and discover hope in the face of ambiguous losses. In Part I readers are introduced to the concept of ambiguous loss and shown how such losses relate to concepts of the family, definitions of trauma, and capacities for resilience. In Part II Boss leads readers through the various aspects of and target points for working with those suffering ambiguous loss. From meaning to mastery, identity to ambivalence, attachment to hope–these chapters cover key states of mind for those undergoing ambiguous loss. The Epilogue addresses the therapist directly and his or her own ambiguous losses. Closing the circle of the therapeutic process, Boss shows therapists how fundamental their own experiences of loss are to their own clinical work. In Loss, Trauma, and Resilience, Boss provides the therapeutic insight and wisdom that aids mental health professionals in not "going for closure," but rather building strength and acceptance of ambiguity. What readers will find is a concrete therapeutic approach that is at once directive and open to the complex contexts in which people find meaning and discover hope in the face of ambiguous losses.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. - Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies - Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. - Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

This new edition reflects the growing use of short term therapy across a variety of settings. Packed with new material on key issues, the book explores the therapeutic relationship, the length of therapy and the evidence base for various forms of therapy. This is key reading for anyone wishing to incorporate a psychodynamic element in their work.