This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

The United States is among the wealthiest nations in the world, but it is far from the healthiest. Although life expectancy and survival rates in the United States have improved dramatically over the past century, Americans live shorter lives and experience more injuries and illnesses than people in other high-income countries. The U.S. health disadvantage cannot be attributed solely to the adverse health status of racial or ethnic minorities or poor people: even highly advantaged Americans are in worse health than their counterparts in other, "peer" countries. In light of the new and growing evidence about the U.S. health disadvantage, the National Institutes of Health asked the National Research Council (NRC) and the Institute of Medicine (IOM) to convene a panel of experts to study the issue. The Panel on Understanding Cross-National Health Differences Among High-Income Countries examined whether the U.S. health disadvantage exists across the life span, considered potential explanations, and assessed the larger implications of the findings. U.S. Health in International Perspective presents detailed evidence on the issue, explores the possible explanations for the shorter and less healthy lives of Americans than those of people in comparable countries, and recommends actions by both government and nongovernment agencies and organizations to address the U.S. health disadvantage.

Human activities influence the chemical and physical properties of the atmosphere; examples are increases in troposphere concentrations of ozone, carbon dioxide, oxides of nitrogen and sulfur, heavy metals and UV-B radiation. Many of these changes can alter the physiological status of terrestrial vegetation through either inhibition or enhancement of growth and reproduction, thereby influencing the ability of sensitive plants to compete for limited resources. As a result, air pollution stress may be changing the genetic structure of plant populations. In this book, leading researchers with a broad, interdisciplinary range of expertise discuss the known and measurable effects of pollution on terrestrial vegetation within the framework of ecological genetics, as well as suitable experimental methodologies to analyze the often novel or unusual effects of such environmental stresses. For environmental researchers and managers, Ecological Genetics and Air Pollution will be a welcomed introduction to this field of growing importance for long-term ecological studies.

Biodiversity is the delicate ecological balance within biological systems such as species and populations. Evidence suggests air pollution disrupts and impoverishes ecosysytems processes, and genetic and population diversity. Based on a symposium conducted by the EPA's Environmental Research Laboratory, this book pulls together current knowledge on the subject, assesses its relevance, and offers a framework for future research on the impact of air pollution on biodiversity through all levels of biological organization. This text is particularly timely due to acid rain and other toxic problems. The text also discusses the best available control technology, management practices, alternative chemicals, and legislative ways to reduce the impact of air pollution on biodiversity.

Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.

"This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans, which met in Lyon, 8-15 October 2013."

Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches. - Summarizes and updates information on antibiotics and AMR/ARGs production and its fate and transport in the environment - Includes phytoremediation and bioremediation technologies for environmental management - Provides analysis of risk assessment of antibiotic resistance genes to help understand the environmental and socioeconomic impacts of antibiotics and AMR/ARGs

Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.

Comprehensive and global in scope, Environmental Pollution and Plant Responses provides an analysis of the research on the factors contributing to the deteriorating environmental quality and its effect on plant performance. The issues include: environmental pollution and global climate change, response patterns of plants at different levels, mechanisms of interaction, tolerance strategies and future research prospects. The author evaluates trends and gives management strategies for abating the problem. This volume highlights the complexities of environmental problems and the affect of pollution on every level of the ecosystem.

Air pollutants provide environmental conditions that drastically differ in many respects from those to which forest trees are naturally adapted. Leading experts in the field here consider these questions of immediate relevance arising from the changing environment: (1) Do air pollutants introduce effects of selection that differ from those known for populations that are not subject to such stress conditions? (2) If air pollutants introduce quantitatively or even qualitatively novel selective effects, which consequences might arise from the adaptation of forest tree populations to the present conditions as well as for the preservation of adaptability to future conditions? In addition to these questions, concepts for preservation of genetic resources are discussed.