Six document facsimile reproductions of letters and paragraphs sent to the Viceroy of New Spain during early exploration of greater California; includes correspondence from early merchant Sebastian Vizcaino and Franciscan friar Fray Junipero Serra. Handwritten on documents 14, 16 and 17: "Photographed from the original preserved in the "Archive General de Indias" de Sevilla, under Royal Order dated Madrid December 26,th 1883 for Adolph Sutro, Esq. of San Francisco, California."

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A thorough inventory of research resources in American repositories, the Guide lists collections in the history of chemistry and chemical engineering, the chemical and pharmaceutical industries, and a number of related chemical process industries and businesses, from personal and professional papers of chemical scientists and engineers to business records of the chemical process industries.

History of early Spanish colonization of California. Historian Eldredge writes of the land march of Portola in 1769, culminating in the discovery of San Francisco Bay. E.J. Molera writes of Portola after he left California, and of the first ship to enter San francisco Bay (the packet boat San Carlos) under the command of Don Juan Manuel de Ayala. Included are Molera's translations of Ayala's report to the Viceroy of New Spain, Ayala's description of San Francisco Bay and Pilot de Canizares' report to Ayala of the reconnaissance of the Bay. Illustrations include the first survey and map of San Francisco Bay from a photograph of the Pilot's original drawing attached to the log of the San Carlos in Seville.