This authoritative new book details the most recent advances in clinical neuroscience, from neurogenetics to the study of consciousness.

This book covers recent advances in the understanding of brain structure, function and disorders based on the fundamental principles of physics. It covers a broad range of physical phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the mind. It provides novel insights into the devastating brain disorders of the mind such as schizophrenia, dementia, autism, aging or addictions, as well as into the new devices for brain repair. The book is aimed at basic researchers in the fields of neuroscience, physics, biophysics and clinicians in the fields of neurology, neurosurgery, psychology, psychiatry.

Great advances have been made in recent years toward a better understanding of the healthy brain and the physical basis of psychiatric disorder. This text brings together contributions from leading international authorities to provide a timely and multidisciplinary overview of this fast developing area. This book provides broad coverage ranging from epilepsy and schizophrenia to basal ganglia disorder and brain lesions. In many cases, a clinically oriented chapter is paired with one that describes the basic science that underpins it, and considerable attention is given to the impact of new technologies, such as structural and functional neuroimaging. This book highlights the basic pathophysiological mechanisms of multifaceted clinical manifestations to provide a valuable review of current neuropsychiatry. It will be welcomed by clinicians, researchers, and students alike from neuroscience to neuropsychology and psychiatry.

Great advances have been made in recent years toward a better understanding of the healthy brain and the physical basis of psychiatric disorder. This text brings together contributions from leading international authorities to provide a timely and multidisciplinary overview of this fast developing area. This book provides broad coverage ranging from epilepsy and schizophrenia to basal ganglia disorder and brain lesions. In many cases, a clinically oriented chapter is paired with one that describes the basic science that underpins it, and considerable attention is given to the impact of new technologies, such as structural and functional neuroimaging. This book highlights the basic pathophysiological mechanisms of multifaceted clinical manifestations to provide a valuable review of current neuropsychiatry. It will be welcomed by clinicians, researchers, and students alike from neuroscience to neuropsychology and psychiatry.

The human brain is made up of 85 billion neurons, which are connected by over 100 trillion synapses. For more than a century, a diverse array of researchers searched for a language that could be used to capture the essence of what these neurons do and how they communicate – and how those communications create thoughts, perceptions and actions. The language they were looking for was mathematics, and we would not be able to understand the brain as we do today without it. In Models of the Mind, author and computational neuroscientist Grace Lindsay explains how mathematical models have allowed scientists to understand and describe many of the brain's processes, including decision-making, sensory processing, quantifying memory, and more. She introduces readers to the most important concepts in modern neuroscience, and highlights the tensions that arise when the abstract world of mathematical modelling collides with the messy details of biology. Each chapter of Models of the Mind focuses on mathematical tools that have been applied in a particular area of neuroscience, progressing from the simplest building block of the brain – the individual neuron – through to circuits of interacting neurons, whole brain areas and even the behaviours that brains command. In addition, Grace examines the history of the field, starting with experiments done on frog legs in the late eighteenth century and building to the large models of artificial neural networks that form the basis of modern artificial intelligence. Throughout, she reveals the value of using the elegant language of mathematics to describe the machinery of neuroscience.

With a large focus on memory this edition discusses the functions and elem ents of the brain, how it works, how it breaks down, and various diseases and disorders that affect it.

A Nobel Prize–winning neuroscientist’s probing investigation of what brain disorders can tell us about human nature Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts. In his seminal new book, The Disordered Mind, Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. But sometimes those connections are disrupted. The brain processes that give rise to our mind can become disordered, resulting in diseases such as autism, depression, schizophrenia, Parkinson’s, addiction, and post-traumatic stress disorder. While these disruptions bring great suffering, they can also reveal the mysteries of how the brain produces our most fundamental experiences and capabilities—the very nature of what it means to be human. Studies of autism illuminate the neurological foundations of our social instincts; research into depression offers important insights on emotions and the integrity of the self; and paradigm-shifting work on addiction has led to a new understanding of the relationship between pleasure and willpower. By studying disruptions to typical brain functioning and exploring their potential treatments, we will deepen our understanding of thought, feeling, behavior, memory, and creativity. Only then can we grapple with the big question of how billions of neurons generate consciousness itself.

One of the key topics for establishing meaningful links between brain sciences and education is the development of reading. How does biology constrain learning to read? How does experience shape the development of reading skills? How does research on biology and behaviour connect to the ways that schools, teachers and parents help children learn to read, particularly in the face of disabilities that interfere with learning? This book addresses these questions and illuminates why reading disorders have been hard to identify, how recent research has established a firm base of knowledge about the cognitive neuroscience of reading problems and the learning tools for overcoming them, and finally, what the future holds for relating mind, brain and education to understanding reading difficulties. Connecting knowledge from neuroscience, genetics, cognitive science, child development, neuropsychology and education, this book will be of interest to both academic researchers and graduate students.

Neural Engineering for Autism Spectrum Disorder, Volume Two: Diagnosis and Clinical Analysis presents the latest advances in neural engineering and biomedical engineering as applied to the clinical diagnosis and treatment of Autism Spectrum Disorder (ASD). Advances in the role of neuroimaging, magnetic resonance spectroscopy, MRI, fMRI, DTI, video analysis of sensory-motor and social behaviors, and suitable data analytics useful for clinical diagnosis and research applications for Autism Spectrum Disorder are covered, including relevant case studies. The application of brain signal evaluation, EEG analytics, fuzzy model and temporal fractal analysis of rest state BOLD signals and brain signals are also presented. A clinical guide for general practitioners is provided along with a variety of assessment techniques such as magnetic resonance spectroscopy. The book is presented in two volumes, including Volume One: Imaging and Signal Analysis Techniques comprised of two Parts: Autism and Medical Imaging, and Autism and Signal Analysis. Volume Two: Diagnosis and Treatment includes Autism and Clinical Analysis: Diagnosis, and Autism and Clinical Analysis: Treatment. - Presents applications of Neural Engineering techniques for diagnosis of Autism Spectrum Disorder (ASD) - Includes in-depth technical coverage of assessment techniques, such as the functional and structural networks underlying visuospatial vs. linguistic reasoning in autism - Covers treatment techniques for Autism Spectrum Disorder (ASD), including social skills intervention, behavioral treatment, evidence-based treatments, and technical tools such as Magnetic Resonance Spectroscopy for ASD - Written by engineers for engineers, computer scientists, researchers and clinicians who need to understand the technology and applications of Neural Engineering for the detection and diagnosis of Autism Spectrum Disorder (ASD)

Since the 1990s, many philosophers have drawn on recent advances in cognitive psychology, brain science and evolutionary psychology to inform their work. These three volumes bring together some of the most innovative work by both philosophers and psychologists in this emerging, collaboratory field.