Differential Equations and Applications in Ecology, Epidemics, and Population Problems is composed of papers and abstracts presented at the 1981 research conference on Differential Equations and Applications to Ecology, Epidemics, and Population Problems held at Harvey Mudd College. The reported researches consist of mathematics that is either a direct outgrowth from questions in population biology and biomathematics, or applicable to such questions. The content of this volume are collected in four groups. The first group addresses aspects of population dynamics that involve the interaction between spatial and temporal effects. The second group covers other questions in population dynamics and some other areas of biomathematics. The third group deals with topics in differential and functional differential equations that are continuing to find important applications in mathematical biology. The last group comprises of work on various aspects of differential equations and dynamical systems, not essentially motivated by biological applications. This book is valuable to students and researchers in theoretical biology and biomathematics, as well as to those interested in modern applications of differential equations.

This volume contains contributed papers authored by participants of a Conference on Differential Equations and Dynamical Systems which was held at the Instituto Superior Tecnico (Lisbon, Portugal). The conference brought together a large number of specialists in the area of differential equations and dynamical systems and provided an opportunity to celebrate Professor Waldyr Oliva's 70th birthday, honoring his fundamental contributions to the field. The volume constitutes anoverview of the current research over a wide range of topics, extending from qualitative theory for (ordinary, partial or functional) differential equations to hyperbolic dynamics and ergodic theory.

This IMA Volume in Mathematics and its Applications MATHEMATICAL APPROACHES FOR EMERGING AND REEMERGING INFECTIOUS DISEASES: MODELS, AND THEORY METHODS is based on the proceedings of a successful one week workshop. The pro ceedings of the two-day tutorial which preceded the workshop "Introduction to Epidemiology and Immunology" appears as IMA Volume 125: Math ematical Approaches for Emerging and Reemerging Infectious Diseases: An Introduction. The tutorial and the workshop are integral parts of the September 1998 to June 1999 IMA program on "MATHEMATICS IN BI OLOGY. " I would like to thank Carlos Castillo-Chavez (Director of the Math ematical and Theoretical Biology Institute and a member of the Depart ments of Biometrics, Statistics and Theoretical and Applied Mechanics, Cornell University), Sally M. Blower (Biomathematics, UCLA School of Medicine), Pauline van den Driessche (Mathematics and Statistics, Uni versity of Victoria), and Denise Kirschner (Microbiology and Immunology, University of Michigan Medical School) for their superb roles as organizers of the meetings and editors of the proceedings. Carlos Castillo-Chavez, es pecially, made a major contribution by spearheading the editing process. I am also grateful to Kenneth L. Cooke (Mathematics, Pomona College), for being one of the workshop organizers and to Abdul-Aziz Yakubu (Mathe matics, Howard University) for serving as co-editor of the proceedings. I thank Simon A. Levin (Ecology and Evolutionary Biology, Princeton Uni versity) for providing an introduction.

This book groups material that was used for the Marrakech 2002 School on Delay Di?erential Equations and Applications. The school was held from September 9-21 2002 at the Semlalia College of Sciences of the Cadi Ayyad University, Marrakech, Morocco. 47 participants and 15 instructors originating from 21 countries attended the school. Fin- cial limitations only allowed support for part of the people from Africa andAsiawhohadexpressedtheirinterestintheschoolandhadhopedto come. Theschoolwassupportedby?nancementsfromNATO-ASI(Nato advanced School), the International Centre of Pure and Applied Mat- matics (CIMPA, Nice, France) and Cadi Ayyad University. The activity of the school consisted in courses, plenary lectures (3) and communi- tions (9), from Monday through Friday, 8. 30 am to 6. 30 pm. Courses were divided into units of 45mn duration, taught by block of two units, with a short 5mn break between two units within a block, and a 25mn break between two blocks. The school was intended for mathematicians willing to acquire some familiarity with delay di?erential equations or enhance their knowledge on this subject. The aim was indeed to extend the basic set of knowledge, including ordinary di?erential equations and semilinearevolutionequations, suchasforexamplethedi?usion-reaction equations arising in morphogenesis or the Belouzov-Zhabotinsky ch- ical reaction, and the classic approach for the resolution of these eq- tions by perturbation, to equations having in addition terms involving past values of the solution.

The dynamics of infectious diseases represents one of the oldest and ri- est areas of mathematical biology. From the classical work of Hamer (1906) and Ross (1911) to the spate of more modern developments associated with Anderson and May, Dietz, Hethcote, Castillo-Chavez and others, the subject has grown dramatically both in volume and in importance. Given the pace of development, the subject has become more and more di?use, and the need to provide a framework for organizing the diversity of mathematical approaches has become clear. Enzo Capasso, who has been a major contributor to the mathematical theory, has done that in the present volume, providing a system for organizing and analyzing a wide range of models, depending on the str- ture of the interaction matrix. The ?rst class, the quasi-monotone or positive feedback systems, can be analyzed e?ectively through the use of comparison theorems, that is the theory of order-preserving dynamical systems; the s- ond, the skew-symmetrizable systems, rely on Lyapunov methods. Capasso develops the general mathematical theory, and considers a broad range of - amples that can be treated within one or the other framework. In so doing, he has provided the ?rst steps towards the uni?cation of the subject, and made an invaluable contribution to the Lecture Notes in Biomathematics. Simon A. Levin Princeton, January 1993 Author’s Preface to Second Printing In the Preface to the First Printing of this volume I wrote: \ . .

"Math and bio 2010 grew out of 'Meeting the Challenges: Education across the Biological, Mathematical and Computer Sciences,' a joint project of the Mathematical Association of America (MAA), the National Science Foundation Division of Undergraduate Education (NSF DUE), the National Institute of General Medical Sciences (NIGMS), the American Association for the Advancement of Science (AAAS), and the American Society for Microbiology (ASM)."--Foreword, p. vi

The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of disease transmission models. It includes (i) an introduction to the main concepts of compartmental models including models with heterogeneous mixing of individuals and models for vector-transmitted diseases, (ii) a detailed analysis of models for important specific diseases, including tuberculosis, HIV/AIDS, influenza, Ebola virus disease, malaria, dengue fever and the Zika virus, (iii) an introduction to more advanced mathematical topics, including age structure, spatial structure, and mobility, and (iv) some challenges and opportunities for the future. There are exercises of varying degrees of difficulty, and projects leading to new research directions. For the benefit of public health professionals whose contact with mathematics may not be recent, there is an appendix covering the necessary mathematical background. There are indications which sections require a strong mathematical background so that the book can be useful for both mathematical modelers and public health professionals.

The volume contains the texts of four courses, given by the authors at a summer school that sought to present the state of the art in the growing field of topological methods in the theory of o.d.e. (in finite and infinitedimension), and to provide a forum for discussion of the wide variety of mathematical tools which are involved. The topics covered range from the extensions of the Lefschetz fixed point and the fixed point index on ANR's, to the theory of parity of one-parameter families of Fredholm operators, and from the theory of coincidence degree for mappings on Banach spaces to homotopy methods for continuation principles. CONTENTS: P. Fitzpatrick: The parity as an invariant for detecting bifurcation of the zeroes of one parameter families of nonlinear Fredholm maps.- M. Martelli: Continuation principles and boundary value problems.- J. Mawhin: Topological degree and boundary value problems for nonlinear differential equations.- R.D. Nussbaum: The fixed point index and fixed point theorems.