This proceedings volume consists of papers presented at the Sixth International Workshop on Computer-Aided Scheduling of Public Transpon, which was held at the Fund~lio Calouste Gulbenkian in Lisbon from July 6th to 9th, 1993. In the tradition of alternating Workshops between North America and Europe - Chicago (1975), Leeds (1980), Montreal (1983), Hamburg (1987) and again Montreal (1990), the European city of Lisbon was selected as the venue for the Workshop in 1993. As in earlier Workshops, the central theme dealt with vehicle and duty scheduling problems and the employment of operations-research-based software systems for operational planning in public transport. However, as was initiated in Hamburg in 1987, the scope of this Workshop was broadened to include topics in related fields. This fundamental alteration was an inevitable consequence of the growing demand over the last decade for solutions to the complete planning process in public transport through integrated systems. Therefore, the program of this workshop included sections which dealt with scheduling problems and computerized systems for operational planning as well as sections on network planning and data management.

This volume consists of papers presented at the Fifth International Workshop on Computer Aided Scheduling of Public Transport, which was held in Montreal from August 19th to the 23rd, 1990. Since the first Workshop in Chicago in 1975 the field had matured considerably. In 1975, there were no presentations that described systems which had been implemented and used on a regular basis. By 1980, in Leeds, and certainly by 1983, in Montreal, several systems were in regular use. They were based on both heuristics and mathematical programming techniques. In 1990, there were more than one hundred transit companies using computer-aided scheduling tools in their regular operations. The scope of the Workshop was broadened in 1987, in Hamburg, so that topics related to scheduling may be introduced. We find, for example, in this book several papers on the technology related to the collection of data and/or the data bases required for scheduling and planning activities.

This volume consists of papers presented at the Fourth International Workshop on Computer-Aided Scheduling of Public Transport, which was held in Hamburg from 28th to 31st July 1987. The first of this series of Workshops was held in Chicago in 1975. Papers presented then tended to look forward to what might be done in the future application of computers to problems in transit scheduling. No presentations described systems which had been implemented and were being used on a regular basis, although a few papers discussed apparently successful once-off applications in both bus scheduling and bus crew scheduling (or run-cutting). However, within a few months of the end of that first workshop some systems had been implemented, both in Europe and in North America. By the time of the second Workshop, in Leeds in 1980, several systems were in regular use. Most of the crew scheduling implementations were based on heuristic methods (e.g., RUCUS), although mathematically based methods were being used in Quebec City and in Hamburg, and several papers described further mathematical methods in the course of development. A wide variety of bus scheduling approaches was reported, many of them being in regular use.

This proceedings volume consists of selected papers presented at the Eighth International Conference on Computer-Aided Scheduling 0/Public Transport (CASPT 2000), which was held at the conference center of the Konrad rd Adenauer-Foundation in Berlin, Germany, from June 2pt to 23 , 2000. The CASPT 2000 is the continuation of aseries of international workshops and conferences presenting recent research and progress in computer-aided scheduling in public transport.Previous workshops and conferences were held in • Chicago (1975), • Leeds (1980), • Montreal (1983 and 1990), • Hamburg (1987), • Lisbon (1993) and • Cambridge, Mass. (1997).1 With CASPT 2000, our series of workshops and conferences celebrated th its 25 anniversary. Starting with a Workshop on Automated Techniques [or Scheduling 0/ Vehicle Operators [or Urban Public Transportation Services in 1975 the scope and purpose has broadened since and still continues to do so. The previous workshops and conferences were focused on public mass transit, and while this remained the primary focus ofthe 2000 conference, it included also computer-aided scheduling methods being developed and applied in re lated means of passenger transport systems. Commonalities regarding op erations research techniques such as, e.g., column generation techniques and 1 While there were no formal proceedings for the first workshop but only a p- printed copy of all papers issued to participants on arrival, the subsequent ones are weil documented as folIows: Wren, A. (Ed.) (1981). Computer Scheduling 0/ Public Transport. North Holland, Amsterdam.

This proceedings volume consists of papers presented at the Sixth International Workshop on Computer-Aided Scheduling of Public Transpon, which was held at the Fund~lio Calouste Gulbenkian in Lisbon from July 6th to 9th, 1993. In the tradition of alternating Workshops between North America and Europe - Chicago (1975), Leeds (1980), Montreal (1983), Hamburg (1987) and again Montreal (1990), the European city of Lisbon was selected as the venue for the Workshop in 1993. As in earlier Workshops, the central theme dealt with vehicle and duty scheduling problems and the employment of operations-research-based software systems for operational planning in public transport. However, as was initiated in Hamburg in 1987, the scope of this Workshop was broadened to include topics in related fields. This fundamental alteration was an inevitable consequence of the growing demand over the last decade for solutions to the complete planning process in public transport through integrated systems. Therefore, the program of this workshop included sections which dealt with scheduling problems and computerized systems for operational planning as well as sections on network planning and data management.

The scope of this synthesis is to (1) search out useful information on the use of computer-aided scheduling and dispatch (CASD) in demand-responsive transit (DRT) services, (2) develop an amalgamation or compendium of the current knowledge and successful practices used in computerizing the functions necessary to efficiently and effectively operate such DRT services, and (3) report on measures used to resolve specific problems in planning and implementing CASD. The ultimate objective in compiling a considerable storehouse of information is to make this information available to the public transit community. Private and nonprofit organizations that are providing DRT services will similarly benefit from a review of these results.

This volume consists of selected papers presented at the Ninth International Conference on Computer-Aided Scheduling of Public Transport. Coverage includes the use of computer-aided methods and operations research techniques to improve: information management; network and route planning; vehicle and crew scheduling and rostering; vehicle monitoring and management; and practical experience with scheduling and public transport planning methods.

This book contains eleven chapters describing some of the most recent methodological operations research developments in transportation. It is structured around the main transportation modes, and each chapter is written by a group of well-recognized researchers. Because of the major impact of operations research methods in the field of air transportation over the past forty years, it is befitting to open the book with a chapter on airline operations management. This book will prove useful to researchers, students, and practitioners in transportation and will stimulate further research in this rich and fascinating area. - Volume 14 examines transport and its relationship with operations and management science - 11 chapters cover the most recent research developments in transportation - Focuses on main transportation modes-air travel, automobile, public transit, maritime transport, and more

Provides detailed information about the signal transduction pathways used by interferons to activate gene transcription. In addition, this book discusses how the same pathways are used by many other cytokines and thus provide a forum for cross-talk among these important biological response modifiers. Additionally, the book introduces the interferon system and describes the interferon-inducible genes whose products are responsible for the cellular actions of interferons. The nature of the interferon receptors and how the transcriptional signals are transmitted from the receptors on the cell surface to the genes in the nucleus are discussed in detail. Finally, the use of similar pathways of signal transduction by other cytokines is highlighted.