The study of breast cancer has involved comparative pathology since the 1890s. The genes that are associated with breast cancer in humans cause cancer in genetically modified mice and rats. This publication opens the way for the examination of other mammalian species.

This book highlights the similarities and differences in the pathology of the genital and urinary tracts in males and females.

This revised and updated second edition contains multiple microscopic illustrations of all diagnostic entities and ancillary techniques, providing a comprehensive, authoritative guide to all aspects of serous effusions. It now includes the many new antibodies which have been tested since the previous edition, as well as a discussion on next-generation sequencing and molecularly targeted therapy. Section one covers diagnosis for benign and malignant effusions while section two discusses biology, therapy, and prognosis highlighting clinical approaches that may be of value. Serous Effusions provides an indispensable guide to all aspects of current practice for cytopathologists, cytotechnicians, pathologists, clinicians and researchers in training and practice.

The Second Edition of this gold-standard text and reference provides a comprehensive description of breast pathology in a clinical context, with emphasis on morphological descriptions of breast cancer in all its many variations. Updates include new information on sentinel lymph node biopsy and increased coverage of needle core biopsy. Dr. Rosen also discusses a new staging system and advances in prognostic markers. More than 2,700 illustrations--including more than 2,000 in full color--provide the true-to-life perspective essential to accurate diagnosis, prognosis, and management.

WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.

Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.

This is the third volume in the Essentials of Diagnostic Gynecological Pathology series sponsored by the British Association of Gynecological Pathologists. Focusing on cervical pathology, it provides an update on current diagnostic criteria, the use of biomarkers and specimen handling. It serves as a quick desktop reference facilitating accurate diagnosis, and also provides detailed descriptions and an exhaustive reference list for more in-depth study. Sections devoted to the changing landscape of cervical screening, current management and future directions are included. Standardized terminology, the biology of HPV-related pre-invasive disease, and the staging of early cervical cancers are discussed. As most histopathology departments receive many gynecological specimens, Pathology of the Cervix has been written to be useful diagnostically to general as well as specialist gynecological pathologists and pathologists in training. Gynecologists, oncologists, dermatologists, genitourinary physicians and cancer nurse specialists will find expert insights here that will help in treatment and counselling of their patients.​

An updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. Readers will also benefit from: A thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice An exploration of concepts related to validating animal models, including the Cinderella Effect Practical discussions of basic necropsy methods and grading lesions for computational analyses Concise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.