Recent Highlights in the Discovery and Optimization of Crop Protection Products highlights the most prominent, recent results in the search for safe and effective new crop protection products. With a focus on the design, synthesis, optimization and/or structure-activity relationships of new chemistries targeting insect, disease, weed, nematode, vector and animal parasite control, the book also includes recent developments in crop enhancement chemistries and new approaches to crop protection products. The inclusion of information on testing tools, green chemistry approaches, and the latest discovery tools, like modeling, structure-based design, and testing tools makes this volume complete. Based on key presentations given at the 14th International IUPAC conference on Crop Protection, May 19-24, 2019 in Ghent, Belgium, this book includes the many exciting new discoveries and findings reported. It is designed to inspire additional research and advancement in the field. - Based on science presented at the 2019 International Union of Pure and Applied Chemistry Conference on Crop Protection - Provides real-world perspectives on pesticide and disease control progress - Presents scientific developments from an international array of contributing authors

The leading reference on this topic has just gotten better. Building on the success of the previous two editions, all the chapters have been updated to reflect the latest developments in the field, and new chapters have been added on picolinic acids, oxathiapiprolin, flupyradifurone, and other topics. This third edition presents the most important active ingredients of modern agrochemicals, with one volume each for herbicides, fungicides, and insecticides. The international team of first-class authors from such renowned crop science companies as Bayer, Syngenta, Dow AgroSciences, DuPont (now Corteva Agriscience), and BASF, address all crucial aspects from the general chemistry and the mode of action to industrial-scale synthesis, as well as from the development of products and formulations to their application in the field. A comprehensive and invaluable source of timely information for all of those working in modern biology, including genetics, biochemistry and chemistry, and for those in modern crop protection science, whether governmental authorities, researchers in agrochemical companies, scientists at universities, conservationists, or managers in organizations and companies involved in improvements to agricultural production.

In this fascinating book, Graham Matthews takes the reader through the history of the development and use of chemicals for control of pests, weeds, and vectors of disease. Prior to 1900 only a few chemicals had been employed as pesticides but in the early 1940s, as the Second World War raged, the insecticide DDT and the herbicide 2-4-D were developed. These changed everything. Since then, farmers have been using a growing list of insecticides, herbicides and fungicides to protect their crops. Their use has undoubtedly led to significant gains in agricultural production and reduction in disease transmission, but also to major problems: health concerns for both users of pesticides and the general public, the emergence of resistance in pest populations, and environmental problems. The book examines the development of legislation designed to control and restrict the use of pesticides, the emergence of Integrated Pest Management (IPM) and the use of biological control agents as part of policy to protect the environment and encourage the sustainable use of pesticides. Finally, the use of new technologies in pest control are discussed including the use of genetic modification, targeted pesticide application and use of drones, alongside basic requirements for IPM such as crop rotations, close seasons and adoption of plant varieties with resistance to pests and diseases.

Pesticide use has changed considerably over the past five decades. Rapid growth characterized the first 20 years, ending in 1981. The total quantity of pesticides applied to the 21 crops analyzed grew from 196 million pounds of pesticide active ingredients in 1960 to 632 million pounds in 1981. Improvements in the types and modes of action of active ingredients applied along with small annual fluctuations resulted in a slight downward trend in pesticide use to 516 million pounds in 2008. These changes were driven by economic factors that determined crop and input prices and were influenced by pest pressures, environmental and weather conditions, crop acreages, agricultural practices (including adoption of genetically engineered crops), access to land-grant extension personnel and crop consultants, the cost-effectiveness of pesticides and other practices in protecting crop yields and quality, technological innovations in pest management systems/practices, and environmental and health regulations. Emerging pest management policy issues include the development of glyphosate-resistant weed populations associated with the large increase in glyphosate use since the late 1990s, the development of Bt-resistant western corn rootworm in some areas, and the arrival of invasive or exotic pest species, such as soybean aphid and soybean rust, which can influence pesticide use patterns and the development of Integrated Pest Management programs.

In recent decades, repeated use of herbicides in the same field has imposed selection for resistance in species that were formerly susceptible. On the other hand, considerable research in the private and public sectors has been directed towards introducing herbicide tolerance into susceptible crop species. The evolution of herbicide resistance, understanding its mechanisms, characterisation of resistant weed biotypes, development of herbicide-tolerant crops and management of resistant weeds are described throughout the 36 chapters of this book. It has been written by leading researchers based on the contributions made at the International Symposium on Weed and Crop Resistance to Herbicides held at Córdoba, Spain. This book will be a good reference source for research scientists and advanced students.

This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.

This book contains 33 papers, presented at the meeting "Integrated Crop protection in Cereals", on recent developments in research into integral control of invertebrate pests, diseases and weeds, together with economic appraisals of applying such research to model farming systems.