This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.

Each volume in this richly illustrated series, published in association with the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format, with high-resolution color photomicrographs, tables, and lists of key specific morphologic criteria. Example vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume provides comprehensive coverage of both surgical pathology and cytopathology of breast lesions. With a focus on malignant tumors, the full spectrum of inflammatory disorders, benign lesions, and hyperplasias are also covered in detail. Advantages and disadvantages of aspiration and core biopsy are discussed, as well as ancillary testing such as hormonal and molecular markers. With over 200 printed photomicrographs and a DVD-ROM offering all images in a downloadable format, this is an important resource for all anatomic pathologists.

Breast cytopathology is a field characterized by practicality and diagnostic efficacy. This book focuses mainly on morphology, with helpful hints for recognizing benign lesions and the main features of malignancy. It reviews specific features of various lesions and the consequences of the diagnosis for the management of the patient. Each chapter contains high-quality cytology images accompanying the descriptions, including comparison images to distinguish the most important morphological features and to help in the differential diagnosis. Fine needle aspiration cytology (FNAC) sampling and preparation technique, fixation, staining, and principles of its interpretation are covered. Immunocytochemistry and ancillary techniques are outlined, as well as the main clinical and radiological features of breast lesions, and the cytological diagnostics of axillary lymph nodes. This publication will be of great use to medical practitioners in their first approach to breast cytopathology, as well as to pathologists and cytotechnicians with little to moderate experience in the field.

Advances in molecular and genetics based diagnostics are driving an increased interest in cytopathology as cytological specimens are the ideal substrate for this new technology. This book fulfills the need for an easy-to-use and authoritative synopsis of breast cytopathology. The volume fits into the lab coat pocket and is ideal for portability and quick reference. Each volume in the series is heavily illustrated with a full color art program, while the text follows a user-friendly outline format.

This book is the culmination of approximately 15 years of experience in breast cytology, which includes the reporting of over 30,000 breast cytology specimens. The cytology of all aspects of the breast is covered, from normal breast with its variations, through benign lesions, both non-neoplastic and neoplastic, to the various types of malignancy, and including male breast. As the primary purpose of any diagnostic procedure on the breast is to detect or rule out malignancy, detailed discussion of breast carcinoma is included. Fine-needle aspiration cytology is dealt with in great detail, from procurement of specimen to preparation and staining of samples. Reporting categories are discussed in depth, with examples of the types of lesion that may be found in each category. Lavish illustrations in full color are included for almost all lesions as pictures illustrate cytologic features much more clearly than do verbose descriptions. Knowing the incidence of a particular entity does not necessarily help in its diagnosis, whereas seeing the morphological features usually leaves a lasting impression. A summary of the cytologic features is included under each topic. Pitfalls that may be encountered are also detailed. The detection of breast cancer is a multidisciplinary endeavor, therefore mammographic and ultrasound images as well as histologic counterparts of the lesions are included, giving the reader a comprehensive view of breast disease.

This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

This book presents the basic concepts for understanding and practicing breast pathology in routine practice. It explains how to tackle the diagnosis, emphasizing diagnostic clues for each entity as well as pitfalls and mimickers. Each chapter has concise, relevant text illustrated by numerous high-quality pictures highlighting the pearls and challenges in the diagnosis of breast lesions. Experts from around the world describe common and rarer conditions affecting the breast. Histology, immunohistochemistry, cytology, radiology and key morphologic criteria are covered. The book includes a chapter dedicated to breast normal histology, which is very important for understanding breast pathology, and a separate chapter for breast radiology, which is essential in understanding and diagnosing the breast lesions especially in a multidisciplinary team. Also, there is a chapter with the latest TNM staging system as well as the recently revised World Health Organization classification of breast tumors. Since in many breast units the cytology is still used to diagnose breast lesions there is a chapter dedicated to this technique. This book is aimed at trainees and practicing pathologists in surgical pathology, particularly those with an interest in breast pathology and those tackling the daily sign-out.

Focuses on the essential information needed by pathologists in order to be able to interpret breast lesions (tumors) appropriately. This book talks about the diagnostic criteria with systematic analysis of differential diagnoses. It also demonstrates value and limitations of immunohistochemistry as a diagnostic adjunct.

Gynecological and Breast Cytopathology Board Review and Self-Assessment is a comprehensive systems-based review of gynecological and breast cytology including cytomorphology, pitfalls and ancillary studies. Presented in a high-yield format with board-type multiple choice questions and detailed answers, this review includes chapters covering Pap smear cytology, colposcopy, breast FNA, and Pelvic washings. The book is also enriched with features to maximize studying and reviewing of cytopathology, including high-yield review with tables emphasizing key points, board exam-type questions, and high quality full-color images. Written by cytologists and cytopathologists with experience in the practice of modern cytology, as well as intensive teaching experience at national and international levels. Gynecological and Breast Cytopathology Board Review and Self-Assessment provides an excellent review, resource, and self-assessment for pathologists, cytopathologists, cytotechnologists, and trainees preparing for board examinations.

WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.