The book examines the social and cultural context of new genetic knowledge associated with breast cancer. It looks at how this knowledge and technologies are used and received in two contrasting social arenas - cancer genetic clinics and a breast cancer research charity.

The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis. Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented.

The discovery of the two inherited susceptibility genes BRCA1 and BRCA2 in the mid-1990s created the possibility of predictive genetic testing and led to the establishment of specific medical programmes for those at high risk of developing breast cancer in the UK, US and Europe. The book provides a coherent structure for examining the diversity of practices and discourses that surround developments linked to BRCA genetics, and to the evolving field of genetics more broadly. It will be of interest to students and scholars of anthropology, sociology, history of science, STS, public health and bioethics. Chapter 8 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 3.0 license.

This Yearbook of Women's History (Jaarboek voor Vrouwengeschiedenis) is dedicated to Gender and Genes. Intruding upon our everyday lives, the world of DNA, genes and genomics has become a challenging field of research, both clinical and biomedical as well as socio-cultural. It is also a challenging topic for a Yearbook which traditionally focuses on women and gender from a historical point of view. Gender issues are part and parcel of genes and genomics in scientific research and socio-cultural discourses and representations. Current literature on genes and genomics does not abound in analyses of biomedical and socio-cultural realms where gender aspects are played out and exchanged. This Yearbookmay thus contribute to a field of analysis which contextualizes history from the viewpoint of current biotechnological developments. This volume contains articles on medical cases (reproductive testing and the case of the sex chromosomes, and framing cancer risk in women and men), cultural representations, a portrait of female scientist Rosalin Franklin and interviews with feminist science philosophers Katarina Karkazis and Donna Dickenson.

In this fully revised and updated second edition of An Anthropology of Biomedicine, authors Lock and Nguyen introduce biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics. Drawing on historical and ethnographic work, the book critiques the assumption made by the biological sciences of a universal human body that can be uniformly standardized. It focuses on the ways in which the application of biomedical technologies brings about radical changes to societies at large based on socioeconomic inequalities and ethical disputes, and develops and integrates the theory that the human body in health and illness is not an ontological given but a moveable, malleable entity. This second edition includes new chapters on: microbiology and the microbiome; global health; and, the self as a socio-technical system. In addition, all chapters have been comprehensively revised to take account of developments from within this fast-paced field, in the intervening years between publications. References and figures have also been updated throughout. This highly-regarded and award-winning textbook (Winner of the 2010 Prose Award for Archaeology and Anthropology) retains the character and features of the previous edition. Its coverage remains broad, including discussion of: biomedical technologies in practice; anthropologies of medicine; biology and human experiments; infertility and assisted reproduction; genomics, epigenomics, and uncertain futures; and molecularizing racial difference, ensuring it remains the essential text for students of anthropology, medical anthropology as well as public and global health.

An Anthropology of Biomedicine is an exciting new introduction to biomedicine and its global implications. Focusing on the ways in which the application of biomedical technologies bring about radical changes to societies at large, cultural anthropologist Margaret Lock and her co-author physician and medical anthropologist Vinh-Kim Nguyen develop and integrate the thesis that the human body in health and illness is the elusive product of nature and culture that refuses to be pinned down. Introduces biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics Develops and integrates an original theory: that the human body in health and illness is not an ontological given but a moveable, malleable entity Makes extensive use of historical and contemporary ethnographic materials around the globe to illustrate the importance of this methodological approach Integrates key new research data with more classical material, covering the management of epidemics, famines, fertility and birth, by military doctors from colonial times on Uses numerous case studies to illustrate concepts such as the global commodification of human bodies and body parts, modern forms of population, and the extension of biomedical technologies into domestic and intimate domains Winner of the 2010 Prose Award for Archaeology and Anthropology

This pioneering collection uses Paul Rabinow’s concept of biosociality to chart the shifts in social relations and in ideas about nature, biology and identity brought about by developments in biomedicine.

Cancer is a transnational condition involving the unprecedented flow of health information, technologies, and people across national borders. Such movement raises questions about the nature of therapeutic citizenship, how and where structurally vulnerable populations obtain care, and the political geography of blame associated with this disease. This volume brings together cutting-edge anthropological research carried out across North and South America, Europe, Africa and Asia, representing low-, middle- and high-resource countries with a diversity of national health care systems. Contributors ethnographically map the varied nature of cancer experiences and articulate the multiplicity of meanings that survivorship, risk, charity and care entail. They explore institutional frameworks shaping local responses to cancer and underlying political forces and structural variables. Chapter 3 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781138776937_oachapter3.pdf

What does it mean to know something - scientifically, anthropologically, socially? What is the relationship between different forms of knowledge and ways of knowing? How is knowledge mobilised in society and to what ends? Drawing on ethnographic examples from across the world, and from the virtual and global 'places' created by new information technologies, Anthropology and Science presents examples of living and dynamic epistemologies and practices, and of how scientific ways of knowing operate in the world. Authors address the nature of both scientific and experiential knowledge, and look at competing and alternative ideas about what it means to be human. The essays analyze the politics and ethics of positioning 'science', 'culture' or 'society' as authoritative. They explore how certain modes of knowing are made authoritative and command allegiance (or not), and look at scientific and other rationalities - whether these challenge or are compatible with science.

In the last several decades, there has been a surge of interest in expertise in the social scientific, philosophical, and legal literatures. While it is tempting to attribute this surge of interest in expertise to the emergence and consolidation of a "knowledge society," "post-industrial society," or "network society," it is more likely that the debates about expertise are symptomatic of significant change and upheaval. As the number of contenders for expert status has increased, as the bases for their claims have become more diverse, and as the struggles between these would-be experts intensified, expertise became problematic and contested. In The Oxford Handbook of Expertise and Democratic Politics, Gil Eyal and Thomas Medvetz have brought together a broad group of scholars who have engaged substantively and theoretically with debates regarding the nature of expertise and the social roles of experts to examine these areas within sociology and allied disciplines. The analyses take an historical and relational approach to the topic and are motivated by the sense that growing mistrust in experts represents a danger to democratic politics today. The chapters will be organized into three general parts: key theoretical and historical debates, the politics of expertise, and expertise within and across professional, disciplinary, legal, and intellectual spheres. Among the topics considered here are the value and relevance of the boundary between experts and laypeople; the causes and consequences of mistrust in experts; the meanings and social uses of objectivity; and the significance of recent transformations in the organization of the professions. Bringing together investigations from social scientists, philosophers, and legal scholars into the political dimensions of expertise, this Handbook connects interdisciplinary work done in science and technology studies with the more classic concerns, topics, and concepts of sociologists of professions and intellectuals.