Annotation. This book constitutes the refereed proceedings of the 13th Annual International Symposium on Algorithms and Computation, ISAAC 2002, held in Vancouver, BC, Canada in November 2002. The 54 revised full papers presented together with 3 invited contributions were carefully reviewed and selected from close to 160 submissions. The papers cover all relevant topics in algorithmics and computation, in particular computational geometry, algorithms and data structures, approximation algorithms, randomized algorithms, graph drawing and graph algorithms, combinatorial optimization, computational biology, computational finance, cryptography, and parallel and distributedd algorithms.

The perception of time is crucial for everyday activities from the sleep–wake cycle to playing and appreciating music, verbal communication, to the determination of the value of a particular behavior. With regard to the last point, making decisions is heavily influenced by the duration of the various options, the duration of the expected delays for receiving the options, and the time constraints for making a choice. Recent advances suggest that the brain represents time in a distributed manner and reflects time as a result of temporal changes in network states and/or by the coincidence detection of the phase of different neural populations. Moreover, intrinsic oscillatory properties of neural circuits could determine timed motor responses. This Research Topic, partly an emergence of a Satellite EBBS meeting sponsored by the COST-Action TIMELY, will discuss how time in the physical world is reconstructed, distorted and modified in brain networks by emotion, learning and neuropathology. This Research Topic on Timing contains up-to-date reviews regarding the relationship between time and decision-making with respect to the underlying psychological and physiological mechanisms responsible for anticipation and evaluation processes.