Bionanomaterials are molecular materials composed partially or completely of biological molecules, key biological structures, such as proteins, enzymes, viruses, DNA, biopolymers as well as metal, metal oxides, and carbon nanomaterials with characteristic bioactivity. Bionanomaterials have drawn much attention for their use in a wide range of industrial applications from scaffolds, dental implants, drug delivery, dialysis, biobatteries, biofuel cells, air purification, and water treatment. Therefore, the intensive current research in this area is driven towards the designing and functionalization of bionanomaterials for industrial applications. Fundamentals of Bionanomaterials covers the fundamental aspects, experimental setup, synthesis, properties, and characterization of the different types of bionanomaterial. It discusses the different structure and unique properties of bionanomaterials that can be obtained by modifying their morphology and composition, highlighting a wide range of fabrication techniques of bionanomaterials and critical processing parameters. This is an important reference source for all those seeking to gain a solid understanding of the characterization, properties and processing a variety of bionanomaterial classes. - Explains the major properties and characterization techniques for a range of bionanomaterial classes - Discusses the commercialization of different types of bionanomaterials for a variety of industry sectors - Highlights the challenges and interdisciplinary perspective of bionanomaterials in science, biology, engineering, medicine, and technology, incorporating both fundamentals and applications

This reference text brings together comprehensive reviews of the latest research in the field of bionanomaterials, with a focus on fundamentals and biomedical applications. Detailed coverage of the classification, properties and synthesis of bionanomaterials is provided to enhance readers' understanding. The book combines new ideas to uplift the advancement of bionanomaterials in biomedical research and provides a valuable reference for researchers and advanced students in the fields of biomaterials, bionanotechnology and bioengineering. The major applications covered include nanobiosensing, nanomedicine, diagnostics, therapeutics, tissue engineering and green bionanotechnology. The properties and applications of synthetic bionanomaterials and molecularly-imprinted polymer-based bionanomaterials are also included.

This book introduces readers to the structure and characteristics of nanomaterials and their applications in dentistry. With currently available implant materials, the clinical failure rate varies from a few percent to over 10 percent and new materials are clearly needed. Nanomaterials offer the promise of higher strength, better bonding, less toxicity, and enhanced cytocompatibility, leading to increased tissue regeneration. Mieczyslaw Jurczyk, director of the Institute of Materials Science and Engineering at the Poznan University of Technology in Poland, has drawn from work in his laboratory and elsewhere in Poland to show that nanomaterials have important biological applications including in the stomatognathic system consisting of mouth, jaws, and associated structures. The book is written from a materials science and medical point of view and has 13 chapters and about 400 pages. The book can be divided approximately into three sections: the first five chapters introduce nanobiomaterials, the next five chapters describe their dental applications, and the last chapters describe their biocompatibility. Chapter 3 is a compendium on metallic biomaterials such as stainless steel, cobalt alloys, and titanium alloys; bioactive, bioresorbable polymers; and composites and ceramic biomaterials. The "top-down" approach to producing nanomaterials such as high-energy ballmilling and severe plastic deformation, as well as Feynman’s "bottom-up technique" of building atom by atom, are discussed in the next chapter. Subsequent chapters discuss each material in depth and point out how new architectures and properties emerge at the nanoscale. Chapter 8 is devoted to shape-memory materials, which now include not only NiTi but also polymers and magnetic materials. In order to improve bonding, nanomaterials can be used to synthesize implants with surface roughness similar to that of natural tissues. Chapter 9 is devoted to different surface treatments for Ti-based nanomaterials, such as anodic oxidation to improve the bioactivity of titanium and improve the corrosion resistance of porous titanium and its alloys. The use of carbon in various forms—nanoparticles, nanofibers, nanotubes, and thin films—is discussed next with emphasis on the microstructure and properties of these materials, their implant applications, and their interaction with subcutaneous tissues. Nanomaterials can be used in preventive dentistry and therefore can reduce the amount of dental treatment that is necessary to maintain a healthy mouth as argued in chapter 11. In a subsequent chapter, the author explains osseointegration (direct bone-to-metal interface) from a biological point of view and early tissue response. The mechanism of the interaction between the implanted materials with the cellular protein in the tissues is described. The last chapter discusses the application of new nanostructured materials in permanent and bioresorbable implants, nanosurface dental implants, and nanostructured dental composite restorative materials. This book not only focuses on nanomaterials but also on nanoengineering to achieve the best results in dentistry. It is recommended to anyone interested in nanomaterials and their applications in dental science. People with a background in materials, chemistry, physics, and biology will benefit from it.

Biomaterials and Bionanotechnology examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.

This book covers advances in nanostructured materials across a variety of biomedical applications as the field evolves from development of prototype devices to real-world implementation. It provides an in-depth look at the current state of the art in oxide nanostructures, carbon nanostructures, and 2D material fabrication and highlights the most important biomedical applications and devices of nanomaterials, including drug delivery, medical imaging, gene therapy, biosensors, and diagnostics. FEATURES Presents the findings of cutting-edge research activities in the field of nanomaterials, with a particular emphasis on biological and pharmaceutical applications Details finished and ongoing toxicity evaluations of emerging nanomaterials Offers a multidisciplinary perspective This book is recommended for senior undergraduate and graduate students, professionals, and researchers working in the fields of bioengineering, materials science and engineering, and biotechnology.

This book focuses on the application of nanotechnology in medicine and drug delivery, including diagnosis and therapy. Nanomedicine can contribute to the development of a personalized medicine both for diagnosis and therapy. By interacting with biological molecules at nanoscale level, nanotechnology opens up an immense field of research and applications. Interactions between artificial molecular assemblies or nanodevices and biomolecules can be understood both in the extracellular medium and inside human cells. Operating at nanoscale allows exploitation of physical properties different from those observed at microscale, such as the volume to surface area ratio. A number of clinical applications of nanobiotechnology, such as disease diagnosis, target-specific drug delivery, and molecular imaging are being investigated. Some promising new products are also undergoing clinical trials. Such advanced applications of this approach to biological systems will undoubtedly transform the foundations of diagnosis, treatment, and prevention of disease in the future. Nanomedicine sales reached $16 billion in 2015, with a minimum of $3.8 billion in nanotechnology R&D being invested each year. Global funding for emerging nanotechnology increased by 45% per year in recent years, with product sales exceeding $1 trillion in 2013. As the nanomedicine industry continues to grow, it is expected to have a significant impact on the global economy. This book provides clear, colorful and simple illustrations, tables, and case studies to clearly convey the content to a general audience and reader. This book also discusses the development of nanobiomaterials from biogenic (biological sources) systems for healthcare and disease therapies. This book, therefore, is useful for researchers and academicians in the fields of nanotechnology, medicine, nano-biotechnology and pharmacology.

This book presents multidisciplinary research focusing on the analysis, synthesis, and design of bio and nanomaterials. Merging biophysics, biochemistry, and bioengineering perspectives, it discusses the basic properties of materials and their interaction with biological systems; the development of new medical devices, such as implantable systems; and new algorithms and methods for modeling the mechanical, physical, and biological properties of biomaterials. The book gathers the proceedings of the 3rd International Conference on Bio and Nanomaterials, held on September 29–October 3, 2019, on an MSC cruise ship navigating the Mediterranean Sea. It particularly highlights Horizon 2020 projects, covering topics such as novel synthetic strategies for nanomaterials, the implementation of bio- and smart materials for pharmacological and medical purposes, as well as environmental applications. Intended for a broad audience of academics and professionals, it offers a comprehensive and timely snapshot of the field of biomaterials. In addition to a set of innovative theories together with the necessary practical tools for their implementation, it also addresses the current challenges in the field, fostering new discussions and possible future collaborations between diverse groups.

Synthesis of Bionanomaterials for Biomedical Applications summarizes a range of procedures, including green synthesis of metal nanoparticles, metal oxide nanoparticles, and other types of nanoparticles while also exploring the appropriate use of these nanoparticles in various therapeutic applications such as anticancer, antibacterial, antifungal, drug delivery, and more. The book provides important information for materials scientists and pharmaceutical scientists on the synthesis of various nanoparticles using a variety of eco-friendly bionanomaterials. As concern has arisen regarding the environmental impact caused by some of nanomaterials, as well as their possible toxicity to cells, this book presents information on a new generation of eco-friendly materials. In addition, the green synthesis of nanoparticles shows how environmentally-friendly nanoparticles can be synthesized from different biological sources, such as microbes, fungi, algae and plants. - Provides information on the synthesis and application of eco-friendly bionanomaterials - Offers coverage of nanomaterials generated through green synthesis - Assesses the challenges of manufacturing eco-friendly nanomaterials on an industrial scale

Theranostic Bionanomaterials is an invaluable study of recent advances and trends in the development and application of functional bionanomaterials for theranostic applications. This book describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties and discusses how these functional nanomaterials enable the precise manipulation of architectural, physical and biochemical cell microenvironments in vitro. In addition, it covers how they can act as the carriers of diagnostic or therapeutic agents, thus providing new pathways or strategies for disease diagnosis and treatment. Specific chapters discuss protein delivery, drug delivery, tissue regeneration, bioimaging, biodetection, and much more. This book will be a critical resource for those involved in cutting-edge research in theranostics bionanomaterial. - Focuses on nanofabrication methods of bionanomaterials - Reviews the application of bionanomaterials, with a focus on drug delivery and diagnosis - Describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties

This is a comprehensive overview of bionanotechnology to students in nanotechnology, biotechnology, bionanotechnology, related fields such as biology, chemistry, physics, and materials science and also everyone who is interested in this research area. It describes the definition of bionanomaterials, how they can be synthesized, characterized and applied in different fields. The current status and future of bionanotechnology, as well as its advantages and limitations, are comprehensively discussed throughout the book. This is an entry-level book which is easy for readers to understand its contents. In this book, we tried to identify the definition of bionanotechnology. Briefly, Bionanotechnology is the emerging research field that comes from the intersection of nanotechnology and biotechnology. Nanotechnology is referring to the design, development, and application of materials which at least one dimension at nanometer scale meanwhile biotechnology is developed based on knowledge about living systems and organisms to create or improve different products. The association of nanotechnology and biotechnology pave a way to develop a hybrid technology with unique features. Thus, this novel technology will be used to improve our living standard in different aspects from developing new medicine, food, and functional cosmetics, introducing new methods to analyze and treat cancer to protect environmental problems.