Biology of Methylotrophs introduces the reader to the study of methylotrophs - microorganisms that use reduced one-carbon compounds for growth. The book is divided into five parts. Part I covers the taxonomy, morphology, and ultrastructure of methylotrophic bacteria. Part II discusses the processes involved in their growth and metabolism. Part III talks about the possible applications of methylotrophs and their enzymes in industrial fields as well as chemistry. Part IV deals with the molecular genetics and the gene expression of methylotrophs, and Part V deals with their habitat and role in the environment. The text is recommended for microbiologists who would like to be acquainted with the subject or make further studies about methylotrophs.

This comprehensive volume is a compilation of articles, some written by established scientists, others by young and upcoming methylotrophy researchers.

This short book attempts to give a reader who has a basic biochemical and microbiological background (one to two years at University level) an idea of the ecological, biochemical, physiological and biotechnological importance of methane, methanol and related compounds in the microbial world. Because the book covers several different scientific disciplines, readers may encounter unfamiliar terminology. The glossary at the end of the book defines the more obscure of these. The book has been written during a period of heavy teaching commit ments, and despite the helpful comments of many colleagues, it is likely that errors have crept in. As I have no co-author whom I can blame, I must accept sole responsibility for these! I wish to thank the many friends, students and colleagues who have read all or part of the manuscript: Charlie Bamforth, Rick Gibson, Jeff Green, Theo Hansen, Wim Harder, Geoff Haywood and, above all, Hans van Dijken.

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs

This book provides in-depth insights into the most recent developments in different areas of microbial methane and methanol utilization, including novel fundamental discoveries in genomics and physiology, innovative strategies for metabolic engineering and new synthetic approaches for generation of feedstocks, chemicals and fuels from methane, and finally economics and the implementation of industrial biocatalysis using methane consuming bacteria. Methane, as natural gas or biogas, penetrates every area of human activity, from households to large industries and is often promoted as the cleanest fuel. However, one should not forget that this bundle of energy, carbon, and hydrogen comes with an exceptionally large environmental footprint. To meet goals of long-term sustainability and human well-being, all areas of energy, chemicals, agriculture, waste-management industries must go beyond short-term economic considerations and target both large and small methane emissions. The search for new environment-friendly approaches for methane capture and valorization is an ongoing journey. While it is not yet apparent which innovation might represent the best solution, it is evident that methane biocatalysis is one of the most promising paths. Microbes are gatekeepers of fugitive methane in Nature. Methane-consuming microbes are typically small in number but exceptionally big in their impact on the natural carbon cycle. They control and often completely eliminate methane emission from a variety of biological and geothermal sources. The tremendous potential of these microbial systems, is only now being implemented in human-made systems. The book addresses professors, researchers and graduate students from both academia and industry working in microbial biotechnology, molecular biology and chemical engineering.

A comprehensive, edited volume pulling together research on manipulation of the crop microbiome for climate resilient agriculture Microbes for Climate Resilient Agriculture provides a unique collection of data and a holistic view of the subject with quantitative assessment of how agricultural systems will be transformed in coming decades using hidden treasure of microbes. Authored by leaders in the field and edited to ensure conciseness and clarity, it covers a broad range of agriculturally important crops, discusses the impact of climate change on crops, and examines biotechnologically and environmentally relevant microbes. The book encapsulates the understanding of microbial mediated stress management at field level, and will serve as a springboard for novel research findings and new applications in the field. Chapter coverage includes: the role of the phytomicrobiome in maintaining biofuel crop production in a changing climate; the impact of agriculture on soil microbial community composition and diversity in southeast Asia; climate change impact on plant diseases; microalgae; photosynthetic microorganisms and bioenergy prospects; amelioration of abiotic stresses in plants through multi-faceted beneficial microorganisms; role of methylotrophic bacteria in climate change mitigation; conservation agriculture for climate change resilience; archaeal community structure; mycorrhiza-helping plants to navigate environmental stresses; endophytic microorganisms; bacillus thuringiensis; and microbial nanotechnology for climate resilient agriculture. Clear and succinct chapters contributed and edited by leaders in the field Covers microbes' beneficial and detrimental roles in the microbiome, as well as the functions they perform under stress Discusses the crop microbiome, nutrient cycling microbes, endophytes, mycorrhizae, and various pests and diseases, and their roles in sustainable farming Places research in larger context of climate change's effect on global agriculture Microbes for Climate Resilient Agriculture is an important text for scientists and researchers studying microbiology, biotechnology, environmental biology, agronomy, plant physiology, and plant protection.

Autotrophic and methylotrophic microorganisms are able to grow at the expense of one-carbon compounds (e.g. carbon dioxide, formaldehyde) as the principal carbon sources for the synthesis of cell material, using light, inorganic compounds or one-carbon compounds as energy sources. The study of the special adaptations required in aerobic and anaerobic microorganisms to sustain an autotrophic or methylotrophic mode of life is a fascinating field of research for scientists from various disciplines. Current research efforts not only focus on fundamental aspects, i.e. metabolic pathways and their regulation, ecology, energy conversion and genetics, but also the possible application of these organisms, in waste water treatment, degradation of xenobiotics, single-cell protein production, as biocatalysts for the production of fine chemicals, draws strong attention. The aim of this series is to provide annual reviews on the biochemistry, physiology, ecology, genetics, and application of microbial autotrophs and methylotrophs. The scope of the series includes all aspects of the biology of these microbes, and will deal with phototrophic and chemolithotrophic prokaryotic autotrophs, carboxydobacteria, acetogenic-, methanogenic- and methylotrophic bacteria, as well as methylotrophic eukaryotes. The exciting advances made in recent years in the study of these organisms is reflected in the chapters of this first volume which have been written by experts in the field. We would like to express our sincere thanks to all the contributors for their stimulating and comprehensive chapters.

Extrusive Bacterial Ectosymbiosis of Ciliates.

Microbe Mediated Remediation of Environmental Contaminants presents recent scientific progress in applying microbes for environmental management. The book explores the current existing practical applications and provides information to help readers develop new practices and applications. Edited by recognized leaders in the field, this penetrating assessment of our progress to date in deploying microorganisms to the advantage of environmental management and biotechnology will be widely welcomed by those working in soil contamination management, agriculture, environment management, soil microbiology, and waste management. The polluting effects on the world around us of soil erosion, the unwanted migration of sediments, chemical fertilizers and pesticides, and the improper treatment of human and animal wastes have resulted in serious environmental and social problems around the world, problems which require us to look for solutions elsewhere than established physical and chemical technologies. Often the answer lies in hybrid applications in which microbial methods are combined with physical and chemical ones. When we remember that these highly effective microorganisms, cultured for a variety of applications, are but a tiny fraction of those to be found in the world around us, we realize the vastness of the untapped and beneficial potential of microorganisms. - Explores microbial application redressing for soil and water contamination challenges - Includes information on microbial synthesized nanomaterials for remediation of contaminated soils - Presents a uniquely hybrid approach, combining microbial interactions with other chemical and physical methods