The second edition of this book is intended as a definitive text on biliary tract and gallbladder cancers. Specifically, it will serve as a single-source reference on the current knowledge base for the multidisciplinary management of such cancers and thus covers epidemiological, surgical, radiotherapy, and chemotherapy approaches. A key feature is the demonstration of the impact of cutting-edge technical knowledge on treatment; for example, interventional radiology techniques, novel surgical approaches, and image-guided radiation therapy are all extensively discussed. Diagnosis is also considered in detail, with coverage of novel serum biomarkers, pathologic staging, molecular profiling, and the full range of current and emerging imaging strategies. This book will be an invaluable source of information on new techniques for experienced practitioners, yet is sufficiently concise to offer an introduction to the field for students and community practitioners.

Biliary Tract and Gallbladder Cancer: Diagnosis and Therapy is a comprehensive and definitive discussion of all aspects of the treatment of malignant tumors of the gallbladder and biliary tract. This is the first book to examine these cancers in such depth, as rapid advances in surgical oncology and radiotherapeutic approaches have demanded the full coverage this text provides. The book progresses logically, with early chapters presenting the epidemiologic, pathologic, and pathogenetic characteristics of BT and GB lesions, followed by excellent discussions of clinical and radiologic diagnosis and staging. Finally, the full arsenal of therapeutic approaches is presented, from the local to systemic, established to experimental. Segments throughout detail the most current cutting-edge therapies, making the latest information readily available across a number of subdisciplines. Features of this unique textbook include: An exclusive and comprehensive focus on neoplasms of the gallbladder and biliary tract A multidisciplinary focus, with contributions from medical, surgical, and radiation oncology, pathology, and imaging, and a clear emphasis on team-based approaches to oncologic care The latest clinical research and treatment discussions from international experts Biliary Tract and Gallbladder Cancer serves as the single-source knowledge base for multidisciplinary biliary tract cancer management. It is comprehensive enough to demonstrate new treatments of biliary tract cancer to experienced practitioners, yet concise enough to serve as an introduction to novices in the field.

This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

A new, fully updated edition of the world’s most famous book on liver diseases—with updating of all areas and inclusion of new specific topics, by internationally renowned specialists This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world’s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock's Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock's unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors’ experience, the hallmark of this book. Based on these elements, the 12th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category. Sherlock's Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website. Internationally recognized and loved, world-renowned hepatology book, first published in 1955 Takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock’s clarity and legacy of presentation Full colour throughout with 700 illustrative figures Wide faculty of international contributors Sherlock's Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.

This book covers various aspects of gall bladder cancer, e.g. its epidemiology, etiology, pathology, clinical presentation, diagnosis, investigations, staging, management, prevention, etc. Gall bladder cancer is the most common form of biliary tract cancer worldwide, there are peculiar geographical variations in its incidence; while it is rare in the developed west (North America and Western Europe), high incidence rates are reported from Central and South America, Central and Eastern Europe, East Asia (Japan and Korea) and northern India. In addition, the book addresses a number of related issues including thick walled gall bladder, gall bladder cancer with surgical obstructive jaundice, incidental gall bladder cancer, the role and place of common bile duct excision, the Japanese aggressive surgical approach, management of asymptomatic gall stones, etc. An authoritative work that provides detailed insights into various aspects of gall bladder cancer and its management, the book offers a valuable resource for physicians in high-incidence areas and low-incidence areas alike. It is richly illustrated throughout with radiographs (US, CT, MRI, etc.) and operative and specimen photos.

An interdisciplinary reference book for the diagnosis and treatment of gallbladder and bile duct diseases With recent developments in the management of hepatobiliary diseases including liver transplantation, this new edition aids all members of the team by addressing both the biliary indications for and biliary complications of these procedures. It's divided into three sections on anatomy, pathophysiology, and epidemiology; diagnostic and therapeutic approaches including the latest therapeutic modalities; and specific conditions. Includes more than 250 illustrations for rapid reference. Each chapter now has a Q&A section and begins with a list of objectives outlining the chapter’s goals. In addition, a number of new imaging modalities are presented in this new edition. It takes an integrated medical, surgical and radiological approach, making this invaluable to all members of the team who deal with complications of liver transplantation and the management of patients.

This book covers all liver tumors and lesions that clinically and radiologically mimic liver tumors. It provides readers with a comprehensive overview of this complex and rapidly evolving field. All aspects of surgical pathology are addressed, supplemented by detailed presentations of the lesions’ cell-biologic and molecular features. In addition, the methods employed for diagnosis and diagnostic algorithms are discussed. It appeals to pathologists and hepatologists and serves as an invaluable aid to diagnosis.The field of liver tumors and tumor-like lesions in adults and children has experienced tremendous advances in recent years. Specifically, the recognition of novel entities, deepened insights into known tumors, and refinement of classifications have necessitated continual updates and reappraisals. In addition, previous understanding of hepatic carcinogenesis and tumor progression has been transformed by the very rapid evolution of our understanding of cell biology, genomics, signaling pathways, cell interactions, and mechanisms of invasion and spread of hepatic tumor cells. These general pathology issues must be combined with surgical pathology if a comprehensive understanding of liver tumor pathology is to be achieved.