This book promotes ancient Traditional Chinese Medicine healing wisdom - healing the skin with natural synergy from body, mind and spirit. Dr.Ping Zhang unlocks for the reader the ancient beauty secrets of Traditional Chinese Medicine, bringing the reader safe, all-natural techniques for restoring a healthy inner balance that's reflected in a smooth, youthful, vibrant face.

This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development. There is a gap between basic aging research and the development of intervention technologies. This major obstacle must be overcome before biogerontological interventions can be put into clinical practice. As biogerontology comes to understand aging as a systemic degenerative process, it is clear that there is a pressing need for technologies that enable cells and tissues in a fully developed adult body to be manipulated systemically to combat aging. The authors review advances in the chemistry and engineering of systemic delivery methods and analyze the strengths and limitations of each. The book is organized into six sections. The first offers an overview of the need for systemic delivery technologies alongside the development of anti-aging therapies and describes approaches that will be required for studying the properties and efficiency of carriers for systemic delivery. Sections II, III and IV describe recent advances in a range of strategies that may enable systemic delivery to help combat aging conditions ranging from cell senescence to decline in immune function and hormonal secretion. Section V discusses practical strategies to engineer and optimize the performance of delivery technologies for applications in systemic delivery, along with their working principles. The final section discusses technical and biological barriers that must be overcome as systemic delivery technologies move from research laboratory to clinical applications aimed at tackling aging and age-associated diseases. Benefiting scholars, students and a broader audience of interested readers, the book includes helpful glossary sections in each chapter, as well as sidebars that highlight important notes, and questions for future research.

Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an "antiaging tonic," testosterone's reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an increase in the number of middle-aged and older men using testosterone and the lack of scientific data on the effect it may have on aging males. Studies of testosterone replacement therapy in older men have generally been of short duration, involving small numbers of participants and often lacking adequate controls. Testosterone and Aging weighs the options of future research directions, examines the risks and benefits of testosterone replacement therapy, assesses the potential public health impact of such therapy in the United States, and considers ethical issues related to the conduct of clinical trials. Testosterone therapy remains an attractive option to many men even as speculation abounds regarding its potential.

If there were a pill that was scientifically proven to help you look 10 years younger, lose fat, improve hormonal health, fight pain and inflammation, increase strength/endurance, heal faster, improve your brain health and increase your energy levels, it would be a billion-dollar blockbuster drug. Hundreds of millions of people would be told to start taking it by their doctors every day. And doctors all over the world would call it a "miracle drug." Here's the crazy part: That "drug" exists. But it's not a pill. It's red light therapy! Did you know that light has the power to heal your body and optimize your health? Of course, everyone knows about the importance of vitamin D from sunlight (from UV light). But few are aware that there is another type of light that may be just as vital to our health - red and near-infrared light. Think it's all just hype? Think again! Believe it or not, there are now over 3,000 peer-reviewed scientific studies showing incredible health and anti-aging benefits of red and near-infrared light therapy. But it gets even better... While you used to have to spend $100 or more to get treatments done in a medical or anti-aging clinic (where this technology has been used for decades), new breakthroughs have allowed us to harness these benefits in the comfort of our own home, without the need to spend thousands on an expensive laser device or $100 per treatment at a health/anti-aging clinic. We can now do red light therapy at home, as much as we want, at a tiny fraction of the cost. In this book, Ari Whitten - bestselling author, health expert and founder of The Energy Blueprint - cuts through all the confusion, myths and pseudoscience around this complex topic, and takes you on a deep dive into the science of how to use red/near-infrared light therapy to improve your health, your body and your life in dozens of ways. Inside this book, you'll learn how to use red/near-infrared light therapy to: - Fight skin aging, wrinkles, and cellulite and look 10 years younger - Lose fat (nearly twice as with diet and exercise alone) - Rid your body of chronic inflammation - Fight the oxidative damage that drives aging - Increase strength, endurance, and muscle mass - Decrease pain - Combat hair loss - Build resilience to stress at the cellular level - Speed up wound/injury healing - Combat some autoimmune conditions and improve hormonal health - Optimize your brain function and mood - Overcome fatigue and improve energy levels You'll also get critical information to get the best results, including: - Specific dosing guidelines for every type of treatment (and how to avoid common mistakes) - The 5 "bioactive" types of light that affect human cell function and human health - Which health issues respond best to red/near-infrared light therapy - The big mistakes people make when giving themselves red light treatments (and exactly how to do treatments to get the best results) - The best light devices to get (and why most devices on the market are a waste of money) - Exact protocols for how to use red/near-infrared light therapy for everything from fat loss, to brain optimization, to skin anti-aging Optimal light exposure habits are as essential to good health as good nutrition habits. But the big problem is that, just as many people eat diets of processed junk food and fast food, most people are eating "light diets" of "junk light" and end up with chronic "mal-illumination." This book will show you how to fix that. Red and near-infrared light therapy is one of the biggest health breakthroughs in the last half century. If you're serious about your health and improving your body, it's time to start using this powerful tool in your life. Buy this book NOW to become the healthier, happier, leaner, stronger, youthful person you've always known you could be. You deserve it! Pick up your copy today by clicking the BUY NOW button at the top of this page!

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

The ketogenic diet is one that is very low in carbohydrate, high in fat, with moderate protein. This diet shifts the body into a natural, healthy metabolic state known as nutritional ketosis. In ketosis the body uses fat as its primary source of energy instead of glucose. Some of this fat is converted into an alternative form of fuel called ketones. Ketones are high-potency fuel that boost energy and cellular efficiency and activates special enzymes that regulate cell survival, repair, and growth. When a person is in nutritional ketosis, blood levels of ketones are elevated to therapeutic levels. In response, high blood pressure drops, cholesterol levels improve, inflammation is reduced, blood sugar levels normalize, and overall health improves. Low-fat diets have been heavily promoted for the past several decades as the answer to obesity and chronic disease. However, we are fatter and sicker now more than ever before. Obviously, the low-fat approach has not worked. Our bodies actually need fat for optimal health and function more efficiently using fat for fuel. In this book you will discover how people are successfully using the ketogenic diet to prevent and treat chronic and degenerative disease. Ketone therapy is backed by decades of medical and clinical research, and has proven to be both safe and effective for the treatment of variety of health issues, including the following: Alzheimer’s disease Parkinson’s disease stroke Multiple sclerosis heart disease cancer diabetes obesity metabolic syndrome Crohn’s disease ulcerative colitis irritable bowel syndrome glaucoma macular degeneration migraine headaches sleep disorders It doesn’t stop there. Research is continually discovering conditions that are responding to the ketogenic diet. Many health problems that medical science has deemed incurable or untreatable are being reversed. Medications that were once relied on daily are no longer necessary and are being tossed away. People are discovering that a simple, but revolutionary diet based on wholesome, natural foods and the most health-promoting fats is dramatically changing their lives. It could be the key to changing yours as well.

The 21st century technological development is revolutionizing medicine and health care, bringing new hopes to human suffering by offering cures and treatments which were unthinkable a few decades ago. This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions. Ideally, by means of the newest medical technology, the "body machinery" should be kept fit and at peak performance all life long. Early detection of age-related dysfunction should thus be "fixed" at any age with interventions such as metabolic fine tuning, enhancement, regeneration, restoration or replacement of "body parts" (i.e. organs, skin, bone or muscle). It covers a vast array of domains: from cell therapy to pharmaceutical interventions, from bio-surgery to aesthetic surgery, from human enhancement to fortified food, from smart housing and robots to toxic-free environments. Anti-ageing medicine holds promises but also significant risks and safety issues which are addressesd in this book. It presents the latest scientific evidence on what works or does not work. It also provides public policy recommendations to ensure the protection of consumers and their rights while encouraging research and development. This book is intended for academics, health professionals, business persons, consumers and policy-makers interested in the latest evidence and ethical issues about anti-ageing medicine.

Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

The author dispels the myths and hype surrounding products and procedures and gives advice on what works and what doesn't, what's ridiculously expensive and what's reasonable.