This book provides readers with comprehensive details on the management and measures to protect health against risks to people and environments generated by the use of ionizing and non-ionizing radiation. This book is divided into three sections, namely, Radiation Protection and Measurement; Radiation Therapy; and Radioactivity. The first section covers ionizing radiation protection; population exposure to non-ionizing density; and the system of dosimetry quantities for use in emergency preparedness and response to nuclear or radiological accidents. The second section covers various planning techniques for spinal stereotactic body radiotherapy and the application of radiation technology in the development of a malaria vaccine. The third section discusses environmental radioactivity monitoring using efficient measurements and the assessment of radiation exposure to humans. Also in this section is the evaluation of the effects of chronic radiation exposure on the testes of mice after a nuclear power plant accident.

This account of sources of ionizing radiation and methods of radiation protection describes units of radiation protection, measurement techniques, biological effects, environmental radiation and many applications. Each chapter contains problems with solutions.

This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

An Introduction to Non-Ionizing Radiation provides a comprehensive understanding of non-ionizing radiation (NIR), exploring its uses and potential risks. The information is presented in a simple and concise way to facilitate easy understanding of relevant concepts and applications. Chapters provide a summary and include relevant equations that explain NIR physics. Other features of the book include colorful illustrations and detailed reference lists. With a focus on safety and protection, the book also explains how to mitigate the adverse effects of non-ionizing radiation with the help of ANSI guidelines and regulations. An Introduction to Non-Ionizing Radiation comprises twelve chapters, each explaining various aspects of non-ionizing radiation, including: Fundamental concepts of non-ionizing radiation including types and sources Interaction with matter Electromagnetic fields The electromagnetic wave spectrum (UV, visible light, IR waves, microwaves and radio waves) Lasers Acoustic waves and ultrasound Regulations for non-ionizing radiation. Risk management of non-ionizing radiation The book is intended as a primer on non-ionizing radiation for a broad range of scholars and professionals in physics, engineering and clinical medicine.

Does radiation medicine need more regulation or simply better-coordinated regulation? This book addresses this and other questions of critical importance to public health and safety. The issues involved are high on the nation's agenda: the impact of radiation on public safety, the balance between federal and state authority, and the cost-benefit ratio of regulation. Although incidents of misadministration are rare, a case in Pennsylvania resulting in the death of a patient and the inadvertent exposure of others to a high dose of radiation drew attention to issues concerning the regulation of ionizing radiation in medicine and the need to examine current regulatory practices. Written at the request from the Nuclear Regulatory Commission (NRC), Radiation in Medicine reviews the regulation of ionizing radiation in medicine, focusing on the NRC's Medical Use Program, which governs the use of reactor-generated byproduct materials. The committee recommends immediate action on enforcement and provides longer term proposals for reform of the regulatory system. The volume covers: Sources of radiation and their use in medicine. Levels of risk to patients, workers, and the public. Current roles of the Nuclear Regulatory Commission, other federal agencies, and states. Criticisms from the regulated community. The committee explores alternative regulatory structures for radiation medicine and explains the rationale for the option it recommends in this volume. Based on extensive research, input from the regulated community, and the collaborative efforts of experts from a range of disciplines, Radiation in Medicine will be an important resource for federal and state policymakers and regulators, health professionals involved in radiation treatment, developers and producers of radiation equipment, insurance providers, and concerned laypersons.

This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. Newer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors. - Provides a comprehensive overview of the basic and translational research in DNA repair as a cancer therapeutic target - Includes timely updates from the earlier edition, including Fanconi Anemia cross-link repair, translesion DNA polymerases, chemotherapy induced peripheral neuropathy, and many other new areas within DNA repair and cancer therapy - Saves academic, medical, and pharma researchers time by allowing them to quickly access the very latest details on DNA repair and cancer therapy - Assists researchers and research clinicians in understanding the importance of the breakthroughs that are contributing to advances in disease-specific research