This succinct book guides the trainee through the hurdles of fledgling cytology practice and can also be used throughout the career as an aide memoire by the more experienced. Whilst there are several well established and excellent textbooks on general cytology, these are by and large reference books rather than bench books that can lie beside each individual trainee’s microscope and be resourced continually before and during each case. With numerous illustrations to enthuse the reader and make cytological practice a more enjoyable and educational experience, the book also highlights points of diagnostic difficulty, particularly with regard to the differentiation of neoplastic from non-neoplastic disease. This bench book will be an invaluable reference guide to histo- and cyto-pathology trainees as well as consultants who want a quick refresher/reference point.

Cytology and Cell Physiology, Third Edition focuses on cell cytology and physiology as well as recent advances in the techniques in studying cells, including microscopy. It also describes cell membranes, surface, and physiology; cytoplasmic constituents; nucleus and nucleocytoplasmic reactions; enzyme histochemistry and cytochemistry; viruses within cells; and morphology of the cancer cell. Organized into 13 chapters, this edition begins with a historical overview of cytology, the template hypothesis of protein synthesis, and the respiratory function of mitochondria. It then discusses the subcellular components and their centrifugal isolation, some general principles of microscopy, selected physical and physicochemical methods, applications of enzyme histochemistry to electron microscopy, and structure and physical properties of the plasma membrane. The remaining chapters focus on the endoplasmic reticulum, the Golgi apparatus, the nucleus and its role in cell metabolism, RNA synthesis and movement, the behavior of viruses within cells, and pathological changes in cells. The book concludes with a chapter on the function and metabolism of cancer cells. This book is highly recommended to cytologists, investigators in the field of pathology, and graduate students in biology, biochemistry, physiology, and anatomy.

Covering aspects of Cell Science, ranging from Basic and Applied, to their modern developments including cell cycle and check-point, Cytology and Genetics elucidates all relevant notions thoroughly.

The second edition of this well-received book provides detailed information on the basic and advanced laboratory techniques in histopathology and cytology. It offers clear guidance on the principles and techniques of routine and special laboratory techniques. It also covers advanced laboratory techniques such as immunocytochemistry, flow cytometry, liquid-based cytology, polymerase chain reactions, tissue microarray, molecular technology, etc. The book's second edition covers several important recent topics with many new chapters, such as liquid biopsy, artificial neural network, digital pathology, and next-generation sequencing. Each chapter elucidates basic principle, practical methods, troubleshooting, and clinical applications of the technique. It includes multiple colored line drawings, microphotographs, and tables to illustrate each technique. The book is a helpful guide to the post-graduate students and fellows in pathology, practicing pathologists, as well as laboratory technicians, and research students.

Liquid-based cytology preparations are currently the standard of care for gynecological cytology, and are being increasingly used for non-gynecological cytology. Diagnostic Liquid-Based Cytology serves as a handy guide to diagnostic cytopathology on liquid-based preparations. The authors, renowned experts in the field, provide clear, concise, and practical diagnostic guidance. This handbook equips you to achieve accurate diagnosis of most commonly and uncommonly encountered diseases in exfoliative and aspirated tissue samples from various sites. The key cytopathological features of various diseases are described. The book is lavishly illustrated with dozens of color images that depict the full range of common and rare conditions. Diagnostic Liquid-Based Cytology offers highly practical guidance and information needed to solve common diagnostic challenges in liquid-based cytology preparations. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is an excellent resource not only for practicing pathologists as well as for pathologists-in-training, and will be the perfect practical resource for daily reference in the cytopathology laboratory.

Cibas (pathology, Harvard Medical School) and Ducatman (pathology, West Virginia University) provide practicing and trainee pathologists with a guide to diagnostic interpretation of cytological specimens, with chapters devoted to various and organ systems. Coverage includes the use of special techniques such as immunohistochemistry, flow cytometry, and molecular biology, as well as indications, methods, and diagnostic pitfalls for various conditions. Color medical images are included. This second edition features new chapters on soft tissue methods and laboratory management. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com).

This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.

Although modern cell biology is often considered to have arisen following World War II in tandem with certain technological and methodological advances—in particular, the electron microscope and cell fractionation—its origins actually date to the 1830s and the development of cytology, the scientific study of cells. By 1924, with the publication of Edmund Vincent Cowdry’s General Cytology, the discipline had stretched beyond the bounds of purely microscopic observation to include the chemical, physical, and genetic analysis of cells. Inspired by Cowdry’s classic, watershed work, this book collects contributions from cell biologists, historians, and philosophers of science to explore the history and current status of cell biology. Despite extraordinary advances in describing both the structure and function of cells, cell biology tends to be overshadowed by molecular biology, a field that developed contemporaneously. This book remedies that unjust disparity through an investigation of cell biology’s evolution and its role in pushing forward the boundaries of biological understanding. Contributors show that modern concepts of cell organization, mechanistic explanations, epigenetics, molecular thinking, and even computational approaches all can be placed on the continuum of cell studies from cytology to cell biology and beyond. The first book in the series Convening Science: Discovery at the Marine Biological Laboratory, Visions of Cell Biology sheds new light on a century of cellular discovery.

This edition stresses not just the diagnostic cytological features of the various conditions encountered, but also the diagnostic pitfalls and the grey areas between so as to enable the reader to give more evidence-based reports. In recognition of their rapid expansion, there are new chapters on recent technological developments and on the cytodiagnosis of childhood tumours. A special section on the importance of multidisciplinary team meetings that include the cytopathologist as a core member of the team has also been included at the end of each chapter. As active members of this team, cytopathologists can define their role in the management pathway and thus bring the patient and the microscope together as never before. The full text can be accessed online and images downloaded via Expert Consult.