With hundreds of original photographs, optical micrographs and scanning electron micrographs, this atlas describes the progress of the embryo throughout its development, highlighting the formation and differentiation of organ structures. From the preembryonic and embryo stages to the development of the skeleton and striated muscle, organogenesis of the heart, and development of external genitalia, it provides authoritative answers to the most frequently asked question about the human embryo. With its plethora of outstanding photographs and images, experienced embryologists as well as clinicians and students can compare historical ideas with photographic reality.

Exhaustively illustrated in color with over 1000 photographs, figures, histopathology slides, and sonographs, this uniquely authoritative atlas provides the clinician with a visual guide to diagnosing congenital anomalies, both common and rare, in every organ system in the human fetus. It covers the full range of embryo and fetal pathology, from point of death, autopsy and ultrasound, through specific syndromes, intrauterine problems, organ and system defects to multiple births and conjoined twins. Gross pathologic findings are correlated with sonographic features in order that the reader may confirm visually the diagnosis of congenital abnormalities for all organ systems. Obstetricians, perinatologists, neonatologists, geneticists, anatomic pathologists, and all practitioners of maternal-fetal medicine will find this atlas an invaluable resource.

Here's a rich pictorial review of normal and abnormal human prenatal development. For each body system or region, you'll find a brief description of the developmental plan, with key concepts and terminology, followed by discussions of histological principles, the classification of congenital defects, and basic cellular, molecular, and genetic concepts. An emphasis on morphological patterns in the embryo and fetus makes it easy to understand the structure and function of the adult body and the embryonic basis of birth defects. Summary tables and terminology sections at the end of each chapter, plus an appendix with all major congenital defects and their embryonic basis, make it easy to review course material and prepare for the USMLE.

The first edition of Color Atlas of Fetal and Neonatal Histology was an important step in updating the histology texts available to practicing pathologists and pathology trainees who perform fetal autopsy and/or participate in research involving fetal tissues. It was a well-received volume that filled a major gap in pathology references related to normal histology and provided a comprehensive, state-of-the art review of fetal and neonatal histology. While the basics of fetal histology have changed little in the intervening years since publication of the first edition, this successor edition provides new insights and a fresh perspective. This book contains six new chapters including: blood vessels and lymphatics, external genitalia, eye, ear, skin, and maceration changes. Many existing chapters have also been expanded to address a greater breadth of fetal and neonatal histology such as postnatal testis development and the cardiac conduction system. The “Special Considerations” sections were also expanded in many chapters to address particularly problematic issues within individual organ systems. The book reviews the histology of the major organ systems in the fetus and neonate and provides detailed images, up-to-date references, and practical guidelines for identifying tissues across all gestational ages of development. The second edition of Color Atlas of Fetal and Neonatal Histology serves as the ultimate go-to resource for pathologists and researchers dealing with, and interested in, fetal and neonatal histology. It provides a comprehensive summary of the current status of the field with excellent and extensive illustrative examples that help guide the clinical study of fetal and neonatal histology and stimulate investigative efforts with fetal tissue.

The present anatomical atlas concentrates on the early weeks of prenatal development of the human embryo. It comprises more than 800 scanning electron-microscopic pictures of specimens of exclusively human embryos. The three-dimensional appearing illustrations show the development of the external form of the face, neck, trunk and limbs. Besides, the brain and the viscera of the head, neck, thorax, abdomen and pelvis all dissected into layers are represented in their position and spatial form. The juxtaposition of pictures of temporally close developmental stages reveals the changes in the form of the organs. Photographs of the same organic system are usually shown at the same magnification and clearly demonstrate the growth process. Simple outline drawings provided with the principal nomenclature facilitate the orientation within the specimens. A brief introduction to each chapter explains the most significant developmental steps depicted. This atlas is of great interest not only to anatomists, embryologists, histologists and developmental biologists, but also to biologists, biochemists and geneticists. Moreover, it serves as a valuable reference book for clinicians such as gynecologists, obstetricians, pediatric surgeons and pediatric cardiologists.

Color Atlas of Fetal and Neonatal Histology serves as a comprehensive atlas of the developmental histology of the major organs from 15 weeks gestation to the neonatal period. Each section includes text on basic embryologic processes that influence the development of each organ and highlight major histologic features that correspond with certain developmental periods. In addition, there are many color photomicrographs at key developmental stages to assist the reader in identifying appropriate histologic changes at each developmental stage. This book will be of great value to students of embryology, pathology residents and fellows, and attending pathologists who perform fetal autopsies.

Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.

Unlike conventional single daily observations, time lapse technology provides hundreds of images, which allows pinpointing of key events in the embryo's in vitro development as well as the detection of brief but significant critical changes. This information is beneficial in selecting the most viable embryos from a cohort and increases the chances

The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.