Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

All practitioners and pharmacists interested in treatment with herbal remedies should have this book at their disposal. It is the definitive practice-oriented introduction - now in its fifth edition - to phytotherapy. Methodically classified by organic systems and fields of application, the text provides a quick insight into dosage, form of application and effects of the most important herbal remedies. Only those herbal remedies that are of pharmacological and clinical efficiency have been considered. The authors are highly experienced in the field of postgraduate medical education, and, with this work, present an indispensable reference book for the medical practice.

The standard-setting reference in medical toxicology—trusted as the leading evidencebased resource for poison emergencies A Doody's Core Title for 2017! For decades, one name has been synonymous with the most respected, rigorous perspectives on medical toxicology and the treatment of poisoned and overdosed patients: Goldfrank's Toxicologic Emergencies. Presented in full color, Goldfrank’s delivers essential, patientcenteredcoverage of every aspect of poison management. The editors and authors are recognized as preeminent scholars in their specialties and provide unmatched coverage of all aspects of toxicologic emergencies, from pharmacology and clinical presentation to cutting-edge treatment strategies. Goldfrank's Toxicologic Emergencies, Tenth Edition begins with an examination of medical toxicology principles and techniques. It then reviews the biochemical, molecular, and pathophysiologic basis of toxicology, followed by an intense focus on toxicologic principles related to special patient populations. Features Case studies enhance your understanding of the clinical application of the text material Practical focus on the pathophysiologic basis of medical toxicology The Antidotes in Depth sections delivers the expertise of toxicologists across the world as they present treatments for critically ill poisoned and overdosed patients and allow you to easily identify key issues relating to the use of complex and often unfamiliar therapies The principles of risk management, medicolegal decision making, patient safety, post mortem toxicology and the assessment of ethanol induced impairment described in chapters and Special Considerations emphasize the interface between medical toxicology, the law, and quality care

This comprehensive review of existing and potential anticancer drugs and therapies by leading researchers from academia, government laboratories, and pharmaceutical companies offers essential insight into what has been accomplished and where the experimental therapy of cancer is going. The authoritative contributors illuminate the current status of the major molecules of cancer treatment, ranging from the nitrogen mustards through platinum complexes to interferons, cytokines, growth factors and their inhibitors, and on to immunotoxins, antisense oligonucleotides, and gene therapy. A companion volume by the same editor (Anticancer Drug Development Guide: Preclinical and Clinical Screening and Approval) details the processes by which new anticancer drugs are approved. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.

Presents the latest R & D information on medicinal mushrooms from diverse geographical locations Offers comprehensive coverage of the most important application areas of medicinal mushrooms Includes contributions by eminently experienced researchers in the field of medicinal mushrooms Medicinal mushrooms are increasingly gaining attention worldwide because of their pharmacologically bioactive compounds, which have demonstrated potent and unique clinical properties. Scientific studies carried out during the last decade have confirmed their efficacy in treating a wide range of diseases. Extracts and bioactive compounds obtained from mushrooms have been used medicinally as anticancer, immunomodulator, antibacterial, antiviral, anti-inflammatory, anti-atherosclerotic, neuroprotectant, cardioprotectant, antioxidant, and anti-hypoglycemic agents, and in stem cell-based therapies. Introducing readers to the latest developments in, and ongoing research efforts on, medicinal mushrooms, this book gathers articles contributed by eminent researchers in different disciplines and from around the globe. Highlighting the tremendous potential of mushrooms for the development of new drugs, the topics covered include but are not limited to: Recent progress in research on the pharmaceutical potential of medicinal mushrooms and prospects for their clinicalapplication Edible mushroom neuronutraceuticals: Basis of therapeutics Overview of therapeutic efficacy of mushrooms Mushrooms – a wealth of resources for prospective stem cell-based therapies Mushrooms as potential natural cytostatics

Rufus of Ephesus' treatise On Melancholy represents perhaps the most influential medical monograph from the late first century AD, since his notion of melancholy links two diverse aspects: black bile as a cause for madness and depression and as a sign of intellectual genius. Rufus combines concepts of melancholy developed in the Aristotelian philosophy with concepts of famous physicians such as Hippocrates and Diocles. His ideas strongly influenced subsequent generations of physicians, and especially Galen, and dominated discourses on the topic during the Middle Ages and the Renaissance. Moreover, the reception of Rufus' concepts was not limited to the Western world; in medieval Muslim culture, in particular, his work enjoyed great fame and favor, and many intellectuals read it eagerly.In this volume, the Greek, Latin and Arabic fragments of this work, lost in the original, have been collected for the first time. Arabic sources in particular yield hitherto unknown fragments, thus allowing for new interpretations of this work. The English introduction, translation and commentary reconstruct the main arguments of this important treatise, enabling the interested scholar to obtain easy access to it. Leading scholars contributed interpretative essays which investigate Rufus and his ideas about melancholy in antiquity, the Middle Ages, the Renaissance and the early modern period from different vantage points, including history, philosophy, literature, art history and psychiatry.

Bodies in Balance: The Art of Tibetan Medicine is the first comprehensive, interdisciplinary exploration of the triangular relationship among the Tibetan art and science of healing (Sowa Rigpa), Buddhism, and arts and crafts. Generously illustrated with more than 200 images, Bodies in Balance includes essays on contemporary practice, pharmacology and compounding medicines, astrology and divination, history and foundational treatises. The volume brings to life the theory and practice of this ancient healing art. 2015 Best Art Book Accolade, ICAS Book Prize in the Humanities Category Bodies in Balance: The Art of Tibetan Medicine is the first comprehensive, interdisciplinary exploration of the triangular relationship among the Tibetan art and science of healing (Sowa Rigpa), Buddhism, and arts and crafts. This book is dedicated to the history, theory, and practice of Tibetan medicine, a unique and complex system of understanding body and mind, treating illness, and fostering health and well-being. Sowa Rigpa has been influenced by Chinese, Indian, and Greco-Arab medical traditions but is distinct from them. Developed within the context of Buddhism, Tibetan medicine was adapted over centuries to different health needs and climates across the region encompassing the Tibetan Plateau, the Himalayas, and Mongolia. Its focus on a holistic approach to health has influenced Western medical thinking about the prevention, diagnoses, and treatment of illness. Generously illustrated with more than 200 images, Bodies in Balance includes essays on contemporary practice, pharmacology and compounding medicines, astrology and divination, history and foundational treatises. The volume brings to life the theory and practice of this ancient healing art.

Jabir ibn Hayyan, for a long time the reigning alchemical authority both in Islam and the Latin West, has exercised numerous generations of scholars. To be sure, it is not only the vexed question of the historical authorship and dating of the grand corpus Jabirianum which poses a serious scholarly challenge; equally challenging is the task of unraveling all those obscure and tantalizing discourses which it contains. This book, which marks the first full-scale study of Jabir ever to be published in the English language, takes up both challenges. The author begins by critically reexamining the historical foundations of the prevalent view that the Jabirian corpus is the work not of an 8th-century individual, but that of several generations of Shi'i authors belonging to the following century and later. Tentatively concluding that this view is problematic, the author, therefore, infers that its methodological implications are also problematic. Thus, developing its own methodological matrix, the book takes up the second challenge, namely that of a substantive analysis and explication of a Jabirian discourse, the Book of Stones. Here explicating Jabir's notions of substance and qualities, analyzing his ontological theory of language and unraveling the metaphysics of his Science of Balance, the author reconstructs the doctrinal context of the Stones and expounds its central theme. He then presents an authoritative critical edition of a substantial selection of the text of the Stones, based on all available manuscripts. This critical edition has been translated in its entirety and is provided with exhaustive commentaries and textual notes -- another pioneering feature of this book: for this is the first English translation of a Jabirian text to emerge in print after a whole century. An outstanding contribution is that it announces and presents an exciting textual discovery: the author has found in the Stones a hitherto unknown Arabic translation of part of Aristotle's Categories. Given that we have so far known of only one other, and possibly later, classical Arabic translation of the Greek text, Haq's discovery gives this book an historical importance.