Language demonstrates structure while also showing considerable variation at all levels: languages differ from one another while still being shaped by the same principles; utterances within a language differ from one another while exhibiting the same structural patterns; languages change over time, but in fairly regular ways. This book focuses on the dynamic processes that create languages and give them their structure and variance. It outlines a theory of language that addresses the nature of grammar, taking into account its variance and gradience, and seeks explanation in terms of the recurrent processes that operate in language use. The evidence is based on the study of large corpora of spoken and written language, what we know about how languages change, as well as the results of experiments with language users. The result is an integrated theory of language use and language change which has implications for cognitive processing and language evolution.

Is there a theory that explains the essence of consciousness? Or is consciousness itself an illusion? Am I conscious now? Now considered the 'last great mystery of science', consciousness was once viewed with extreme scepticism and rejected by mainstream scientists. It is now a significant area of research, albeit a contentious one, as well as a rapidly expanding area of study for students of psychology, philosophy, and neuroscience. This edition of Consciousness, revised by author team Susan Blackmore and Emily Troscianko, explores the key theories and evidence in consciousness studies ranging from neuroscience and psychology to quantum theories and philosophy. It examines why the term ‘consciousness’ has no recognised definition and provides an opportunity to delve into personal intuitions about the self, mind, and consciousness. Featuring comprehensive coverage of all core topics in the field, this edition includes: Why the problem of consciousness is so hard Neuroscience and the neural correlates of consciousness Why we might be mistaken about our own minds The apparent difference between conscious and unconscious Theories of attention, free will, and self and other The evolution of consciousness in animals and machines Altered states from meditation to drugs and dreaming Complete with key concept boxes, profiles of well-known thinkers, and questions and activities suitable for both independent study and group work, Consciousness provides a complete introduction to this fascinating field. Additional resources are available on the accompanying companion website: www.routledge.com/cw/blackmore

This volume comprehensively reviews oncology in the precision medicine era of personalized care, latest developments in the field, and indications and clinical trials for the treatment of cancer with targeted therapies, immunotherapy, and epigenetic modulators. It thoroughly addresses concerns of various types of cancers including cancers of the head and neck, lung, colon, esophagus, bladder, pancreas, and breast; melanoma; multiple myeloma; hepatocellular carcinoma; renal cell carcinoma; and sarcomas. It is organized and written in a format that is easy to follow for both clinicians and non-clinical scientists interested in personalized medicine. Chapters cover the identification of the clinical problem and summary of recent findings, tumor biology and heterogeneity, genomics, examples of simple and complex cases, biological pathways, future clinical trials, and financial considerations. Oncology in the Precision Medicine Era: Value-Based Medicine will serve as a useful resource for medical oncologists and healthcare providers tailoring medicine to the needs of the individual patient, from prevention and diagnosis to treatment and follow up.

The displaced are often rendered silent and invisible as they journey in search of refuge. Drawing on historical and contemporary examples from Turkey, the Ottoman Empire, Iraq, Syria, UK, Germany, France, the Balkan Peninsula, US, Canada, Australia, and Kenya, the contributions to this volume draw attention to refugees, asylum seekers, exiles, and forced migrants as individual subjects with memories, hopes, needs, rights, and a prospective place in collective memory. The book's wide-ranging theoretical, literary, artistic, and autobiographical contributions appeal to scholarly and lay readers who share concerns about the fate of the displaced in relation to the emplaced in this age of mass mobility.

Creating Holistic Technology-Enhanced Learning Experiences: Tales of a Future School in Singapore Editors: Lee Yong TAY & Cher Ping LIM The global level of economic, ecological, social, political and cultural integration across nation states and the rapid advancement of technology have brought about transformations that are part of globalisation. Our students are expected to be agents of change rather than passive observers of world events; and at the same time, to live together in an increasingly diverse and complex society and to reflect on and interpret fast changing information. In such a new world order, the holistic development of our students, namely in the cognitive, aesthetics, physical, social and moral, leadership and global domains, is pivotal. This edited book provides descriptive and interpretive accounts of how an elementary school in the FutureSchools@Singapore programme creates holistic technology-enhanced learning experiences for its students at the classroom and school levels. By documenting these accounts and linking them to student learning outcomes, the school will lead the way in providing possible models for the seamless and pervasive integration of information and communication technologies (ICT) into the curriculum for the holistic development of our students.

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This book is an excellent practical compendium of knowledge in the field of HIV and TB drug resistance that will be of immense use to clinicians, nurses, and other caregivers. It provides expert guidance as to what to do in difficult clinical situations and what steps should be taken to prevent the emergence and transmission of drug resistance