The crime thriller, “A Natural Kill”, has action of a movie like “Taken”, the heart of “Forrest Gump” and justice evident in the “Equalizer”. ‘Motion Picture Company Inc. future production.’ Dr. Peter Kalos has no idea that he’s about to find himself at odds with a vicious drug dealer when his work at the hospital leads him to discover a heinous crime perpetrated against a child. Clint Wolf, an infamous hitman known as “The Black Stallion” is brought in to silence the physician, now the lone witness for the prosecution. Clint’s style of murder branded a natural kill relies on high-tech surveillance. He stalks his prey, finds their weaknesses, and then orchestrates a death that seems to be from natural causes. Surveillance reveals the doctor to be a Godly man of strong faith, possessed of saintly virtues. Clint is challenged by what he observes, but then he discovers the doctor’s startling dark secret. Further complications arise when he falls in love with Stacy, a waitress with strong Christian values. The ramifications lead Clint toward a life-and-death struggle with unexpected adversaries.

"This richly illustrated book provides an in-depth natural history of the most poisonous plants on earth, covering everything from the lethal effects of hemlock and deadly nightshade to the uses of such plants in medicine, ritual, and chemical warfare"--Dust jacket.

This volume contains collection of Natural Killer Cell methodologies relevant for both basic and translational research. These methodologies present new developments in the natural killer (NK) cell field, such as understanding the influence of NK cells metabolism on its function, identifying complexity of NK cell subsets through mass cytometry, and determining the emergence of memory NK cells in murine model of MCMV infection. Methods that study NK cell migration and cytotoxicity through endpoint analysis or live single cell imaging are also discussed. Chapters also describe methods pertaining to translational application of NK cells, such as ex vivo expansion of NK cells on K562 cell lines genetically modified to express either membrane bound IL-15 or membrane bound IL-21, large scale NK cell culture, current techniques for engineering NK cells to express chimeric antigen receptors or chemokine receptors using retroviral vectors, electroporation of mRNA, and the natural phenomenon of trogocytosis. Written in the highly successful Methods in Molecular Biology series format, these chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, Natural Killer Cells: Methods and Protocols is a valuable resource for researchers who not only want to understand mechanisms that govern NK cell behavior and diversity, but also for those who want to understand how to systematically evaluate NK cells for adoptive immunotherapy applications.

A fun exploration of the darker side of the natural world reveals the fascinating, weird, often perverted ways that Mother Nature fends only for herself. It may be a wonderful world, but as Dan Riskin (cohost of Discovery Canada’s Daily Planet) explains, it’s also a dangerous, disturbing, and disgusting one. At every turn, it seems, living things are trying to eat us, poison us, use our bodies as their homes, or have us spread their eggs. In Mother Nature Is Trying to Kill You, Riskin is our guide through the natural world at its most gloriously ruthless. Using the seven deadly sins as a road map, Riskin offers dozens of jaw-dropping examples that illuminate how brutal nature can truly be. From slothful worms that hide in your body for up to thirty years to wrathful snails with poisonous harpoons that can kill you in less than five minutes to lustful ducks that have orgasms faster than you can blink, these fascinating accounts reveal the candid truth about “gentle” Mother Nature’s true colors. Riskin’s passion for the strange and his enthusiastic expertise bring Earth’s most fascinating flora and fauna into vivid focus. Through his adventures— which include sliding on his back through a thick soup of bat guano just to get face-to-face with a vampire bat, befriending a parasitic maggot that has taken root on his head, and coming to grips with having offspring of his own—Riskin makes unexpected discoveries not just about the world all around us but also about the ways this brutal world has shaped us as humans and what our responsibilities are to this terrible, wonderful planet we call home.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

"This accessible guidebook is the result of a longstanding collaboration between the Royal Botanic Gardens, Kew and the Medical Toxicology Information Services at Guy's and St. Thomas' Hospital, London. Helpful descriptions and more than 230 photographs will assist you in identifying 132 of the most poisonous plants and plant groups likely to be encountered as pot plants, in flower beds and vegetable plots, and in more natural environments"--Page 4 of cover.

Exploring the relationship between natural law theory and the philosophy of law, Bebhinn Donnelly proposes a new approach to natural law theory - one which addresses some of the tradition's shortcomings, and advances further the approach to Hume's dichotomy. This volume will be of interest to academics in philosophy of law, moral/political philosophy, natural law theorists, and students of jurisprudence internationally.

In this eloquent plea for compassion and respect for all species, journalist and gardener Nancy Lawson describes why and how to welcome wildlife to our backyards. Through engaging anecdotes and inspired advice, profiles of home gardeners throughout the country, and interviews with scientists and horticulturalists, Lawson applies the broader lessons of ecology to our own outdoor spaces. Detailed chapters address planting for wildlife by choosing native species; providing habitats that shelter baby animals, as well as birds, bees, and butterflies; creating safe zones in the garden; cohabiting with creatures often regarded as pests; letting nature be your garden designer; and encouraging natural processes and evolution in the garden. The Humane Gardener fills a unique niche in describing simple principles for both attracting wildlife and peacefully resolving conflicts with all the creatures that share our world.

Basing his argument on natural law, Graham J. McAleer asserts that only public authority has the right to intentionally kill. He draws upon the work of Thomas Aquinas and Francisco de Vitoria, defending the claim that these natural law theorists have developed the best available theory of homicide. To have rule of law in any meaningful sense, the author argues, there must be protections for the guilty and prohibition against killing innocents. Western theories of law have drifted steadily towards the privatization of homicide,despite the fact that it runs counter to rule of law. Public acts of homicide like capital punishment are now viewed by many as barbaric, while a private act of homicide like the starvation of comatose patients is viewed by many as a caring gesture both to patient and family. This subversion of the rule of law is prompted by humanitarian ethics. McAleer argues that humanitarianism is a false friend to those committed to the rule of law. The problem of human vulnerability makes political theology an inescapable consideration for law. Readers will find much to reflect upon in this book. McAleer's argument can be read as a cultural chapter in the history of moral ideas, but also as a close and timely reading of a grim subject.

Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. - Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro - Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies - Color illustrations enhance explanations of the immune system