For centuries, men and women have manned lighthouses to ensure the safe passage of ships. It is a lonely job, and a thankless one for the most part. Until something goes wrong. Until a ship is in distress. In the 23rd century, this job has moved into outer space. A network of beacons allows ships to travel across the Milky Way at many times the speed of light. These beacons are built to be robust. They never break down. They never fail. At least, they aren't supposed to.

The present work describes an integrated computational model of airflow as well as particle dispersion, breakage and deposition in a Dry Powder Inhaler, DPI. The integrated model combines computational fluid dynamics, CFD, an Eulerian/Lagrangian model for particle motion and deposition, and a particle-wall collision model, which are employed to determine the parameters of a multi-compartment model of the DPI. Dynamic population balance models are solved in the compartment model to determine the breakup and deposition of particle agglomerates in the DPI during inhalation. This approach provides detailed information on the dispersion and deposition of powder particles in the DPI connecting formulation properties to key outflow features, e.g. emitted mass and fine particle fraction.

A new optimization model is presented for the short-term management of the energy supply and demand in smart grids. The detailed model includes a flexible demand profile in order to manage the energy requirements by incorporating penalizations in the economic objective function for delays in satisfying energy demand. The MILP model for the optimization of deterministic scenarios is reformulated in order to incorporate discrete and hybrid time representations. This approach allows considering a different granularity of the problem. Finally, the improved performance of the hybrid approach introduced is shown by comparing the performance of these two time representations.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

The best-selling Spectrum series continues with this twenty-third lavishly produced annual. Challenging, controversial, educational, and irreverent, the award-winning Spectrum series reinforces both the importance and prevalence of fantastic art in today's culture. With exceptional images by extraordinary creators, this elegant full-color collection showcases an international cadre of creators working in every style and medium, both traditional and digital. The best artists from the United States, Europe, China, Australia, South America and beyond have gathered into the only annual devoted exclusively to works of fantasy, horror, science fiction, and the surreal, making Spectrum one of the year's highly most anticipated books. Featured in Spectrum 23 are over 300 diverse visionaries. With art from books, graphic novels, video games, films, galleries, advertising and the fine arts, Spectrum is both an electrifying art book for fans and an invaluable resource for clients looking for bright new talent. The entire field is discussed in an invaluable, found-nowhere-else Year In Review. Contact information for each artist is included. Often imitated, never equaled, Spectrum 23 continues the freshness and excellence that was established over twenty years ago.

Perhaps Dotzauer's most famous cello work is his 113 Etudes in four volumes. Masterfully prepared by him, this edition is a reprint of the authoritative G. Schirmer plate 26746 printed around 1917. This is the first volume in the series. 57pps, Extra note and staff paper in back for teacher annotations. Edition Fleury 2013. A must have for any student, teacher or cellist to have in his/her library.

CO2 capture and sequestration (CCS) is a major means to reduce greenhouse gas emissions, especially from centralized energy conversion sites. Many studies have been conducted either on the CO2 capture side or on the sequestration side, but research on CO2 transport, which connects the capture side and the sequestration side, is rather limited. CO2 capture sites and sequestration sites are usually not geographically located in the same region, thus planning and design of CO2 transport infrastructure must be considered before capture and sequestration activities are conducted. Previously, some studies have been conducted to address the optimal planning problem of CO2 pipelines network via a source-sink match approach, which is applicable to early stages of CCS development when the total amount of CO needed to be transported is rather small. However, in scenarios with large amount of CO to be transported, the source-sink match approach appears to be less efficient. In this manuscript, we propose a superstructure based modelling and optimization framework for optimal planning of CO2 transport pipelines network, where all CO2 emissions sources and sequestrations sites can be connected by pipelines, and pump stations can also be built along pipelines to maintain the pressure of CO transported. We also provide a case study of a region in North China, with 45 emissions sources and four sequestration sites. Different configurations of pipelines network are illustrated in scenarios with low, medium, and high CO2 capture rates.

A teen girl races against the clock to prevent a terrible tragedy in this time travel suspense thriller that will keep middle grade and young adult readers on the edges of their seats By both society’s measure and her own, fifteen-year-old Zoe Mahar is pretty much a loser. Then one day she ducks into Spencerport Savings and Loan simply to get out of the rain—and witnesses a bank robbery gone horrifyingly wrong. The good news is that Zoe has a unique ability: she can play back time and repeat events. But it's not an unlimited deal—she can only jump 23 minutes, and her first playback creates an even more disastrous outcome. Zoe has only ten tries to get it right before this particular 23 minutes becomes irreversible. But in the process of trying to become the heroine she doesn't believe she can be, Zoe will learn about herself—and realize that there is more to who she is than she thought.