This book traces the emergence of SARS, in the process examining the global politics and economics of disease. It provides the first behind-the-scenes account of how the global battle against SARS was fought and the incredible research efforts that finally led to identification of the virus.

Could a few fleas really change the world? In the early 1300s, the world was on the brink of change. New trade routes in Europe and Asia brought people in contact with different cultures and ideas, while war and rebellions threatened to disrupt the lives of millions. Most people lived in crowded cities or as serfs tied to the lands of their overlords. Conditions were filthy, as most people drank water from the same sources they used for washing and for human waste. In the cramped and rat-infested streets of medieval cities and villages, all it took were the bites of a few plague-infected fleas to start a pandemic that killed roughly half the population of Europe and Asia. The bubonic plague wiped out families, villages, even entire regions. Once the swollen, black buboes appeared on victims’ bodies, there was no way to save them. People died within days. In the wake of such devastation, survivors had to reevaluate their social, scientific, and religious beliefs, laying the groundwork for our modern world. The Black Death outbreak is one of world history’s pivotal moments.

A vivid, sweeping, and “fact-filled” (Booklist, starred review) history of mankind’s battles with infectious disease that “contextualizes the COVID-19 pandemic” (Publishers Weekly)—for readers of the #1 New York Times bestsellers Yuval Harari’s Sapiens and John Barry’s The Great Influenza. For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion—quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles—resulting in an urbanized, globalized, and unimaginably wealthy world. However, our development has lately become precarious. Climate and population fluctuations and factors such as global trade have left us more vulnerable than ever to newly emerging plagues. Greater global cooperation toward sustainable health is urgently required—such as the international efforts to manufacture and distribute a COVID-19 vaccine—with millions of lives and trillions of dollars at stake. “A timely, lucid look at the role of pandemics in history” (Kirkus Reviews), The Plague Cycle reveals the relationship between civilization, globalization, prosperity, and infectious disease over the past five millennia. It harnesses history, economics, and public health, and charts humanity’s remarkable progress, providing a fascinating and astute look at the cyclical nature of infectious disease.

Recounts the history and effects of the bubonic plague, describes how the disease spread, and offers information about treatment and prevention in the modern world.

The Black Death was the fourteenth century's equivalent of a nuclear war. It wiped out one-third of Europe's population, taking millions of lives. The author draws together the most recent scientific discoveries and historical research to pierce the mist and tell the story of the Black Death as a gripping, intimate narrative.

Developed throughout early modern Europe, lazaretti, or plague hospitals, took on a central role in early modern responses to epidemic disease, in particular the prevention and treatment of plague. The lazaretti served as isolation hospitals, quarantine centres, convalescent homes, cemeteries, and depots for the disinfection or destruction of infected goods. The first permanent example of this institution was established in Venice in 1423 and between the fifteenth and eighteenth centuries tens of thousands of patients passed through the doors. Founded on lagoon islands, the lazaretti tell us about the relationship between the city and its natural environment. The plague hospitals also illustrate the way in which medical structures in Venice intersected with those of piety and poor relief and provided a model for public health which was influential across Europe. This is the first detailed study of how these plague hospitals functioned, where they were situated, who worked there, what it was like to stay there, and how many people survived. Comparisons are made between the Venetian lazaretti and similar institutions in Padua, Verona and other Italian and European cities. Centred on the sixteenth and seventeenth centuries, during which time there were both serious plague outbreaks in Europe and periods of relative calm, the book explores what the lazaretti can tell us about early modern medicine and society and makes a significant contribution to both Venetian history and our understanding of public health in early modern Europe, engaging with ideas of infection and isolation, charity and cure, dirt, disease and death.

A wide-ranging study that illuminates the connection between epidemic diseases and societal change, from the Black Death to Ebola This sweeping exploration of the impact of epidemic diseases looks at how mass infectious outbreaks have shaped society, from the Black Death to today. In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare. A multidisciplinary and comparative investigation of the medical and social history of the major epidemics, this volume touches on themes such as the evolution of medical therapy, plague literature, poverty, the environment, and mass hysteria. In addition to providing historical perspective on diseases such as smallpox, cholera, and tuberculosis, Snowden examines the fallout from recent epidemics such as HIV/AIDS, SARS, and Ebola and the question of the world’s preparedness for the next generation of diseases.

NEW YORK TIMES BESTSELLER • From the Pulitzer Prize-winning author of The Looming Tower—a riveting thriller and “all-too-convincing chronicle of science, espionage, action and speculation” (The Wall Street Journal). At an internment camp in Indonesia, forty-seven people are pronounced dead with acute hemorrhagic fever. When epidemiologist Henry Parsons travels there on behalf of the World Health Organization to investigate, what he finds will have staggering repercussions. Halfway across the globe, the deputy director of U.S. Homeland Security scrambles to mount a response to the rapidly spreading pandemic leapfrogging around the world, which she believes may be the result of an act of biowarfare. And a rogue experimenter in man-made diseases is preparing his own terrifying solution. As already-fraying global relations begin to snap, the virus slashes across the United States, dismantling institutions and decimating the population. With his own wife and children facing diminishing odds of survival, Henry travels from Indonesia to Saudi Arabia to his home base at the CDC in Atlanta, searching for a cure and for the origins of this seemingly unknowable disease. The End of October is a one-of-a-kind thriller steeped in real-life political and scientific implications, filled with the insight that has been the hallmark of Wright’s acclaimed nonfiction and the full-tilt narrative suspense that only the best fiction can offer.

From the Pulitzer Prize–winning author of The Looming Tower, and the pandemic novel The End of October: an unprecedented, momentous account of Covid-19—its origins, its wide-ranging repercussions, and the ongoing global fight to contain it "A book of panoramic breadth ... managing to surprise us about even those episodes we … thought we knew well … [With] lively exchanges about spike proteins and nonpharmaceutical interventions and disease waves, Wright’s storytelling dexterity makes all this come alive.” —The New York Times Book Review From the fateful first moments of the outbreak in China to the storming of the U.S. Capitol to the extraordinary vaccine rollout, Lawrence Wright’s The Plague Year tells the story of Covid-19 in authoritative, galvanizing detail and with the full drama of events on both a global and intimate scale, illuminating the medical, economic, political, and social ramifications of the pandemic. Wright takes us inside the CDC, where a first round of faulty test kits lost America precious time . . . inside the halls of the White House, where Deputy National Security Adviser Matthew Pottinger’s early alarm about the virus was met with confounding and drastically costly skepticism . . . into a Covid ward in a Charlottesville hospital, with an idealistic young woman doctor from the town of Little Africa, South Carolina . . . into the precincts of prediction specialists at Goldman Sachs . . . into Broadway’s darkened theaters and Austin’s struggling music venues . . . inside the human body, diving deep into the science of how the virus and vaccines function—with an eye-opening detour into the history of vaccination and of the modern anti-vaccination movement. And in this full accounting, Wright makes clear that the medical professionals around the country who’ve risked their lives to fight the virus reveal and embody an America in all its vulnerability, courage, and potential. In turns steely-eyed, sympathetic, infuriated, unexpectedly comical, and always precise, Lawrence Wright is a formidable guide, slicing through the dense fog of misinformation to give us a 360-degree portrait of the catastrophe we thought we knew.