Discrete-trials teaching, or DTT, is a very important teaching technique developed by behavior analysts. The DTT Manual has taught numerous groups of individuals to conduct DTT with children with autism in as quickly as 6 hours. The manual is the product of the joint work of Dr. Daniela Fazzio, PhD, BCBA-D and Dr. Garry L. Martin, PhD, Distinguished Professor of Psychology. The manual addresses an area of much need in the field of autism treatment; effective and efficient training for parents and professionals. It was written with them in mind and it has been empirically tested several times, with several university students, paraprofessionals, and parents. It will be easy to navigate for individuals with a high school diploma, regardless of any prior experience in psychology or special education.

In 1948 the first randomized controlled trial was published by the English Medical Research Council in the British Medical Journal. Until then, observations had been uncontrolled. Initially, trials frequently did not confirm the hypotheses to be tested. This phenomenon was attributed to low sensitivity due to small samples, as well as inappropriate hypotheses based on biased prior trials. Additional flaws were recognized and, subsequently, were better accounted for: carryover effects due to insufficient washout from previous treatments, time effects due to external factors and the natural history of the condition under study, bias due to asymmetry between treatment groups, lack of sensitivity due to a negative correlation between treatment responses, and so on. Such flaws, mainly of a technical nature, have been largely corrected and led to trials after 1970 being of significantly higher quality. The past decade has focused, in addition to technical aspects, on the need for circumspection in the planning and conducting of clinical trials. As a consequence, prior to approval, clinical trial protocols are now routinely scrutinized by different circumstantial organs, including ethics committees, institutional and federal review boards, national and international scientific organizations, and monitoring committees charged with conducting interim analyses. This book not only explains classical statistical analyses of clinical trials, but also addresses relatively novel issues, including equivalence testing, interim analyses, sequential analyses, and meta-analyses, and provides a framework of the best statistical methods currently available for such purposes. This book is not only useful for investigators involved in the field of clinical trials, but also for all physicians who wish to better understand the data of trials as currently published.

Now available in paperback for the first time, this book examines trials, civil and criminal, ecclesiastical and secular, in England and Europe between the thirteenth and the seventeenth centuries. Chapters consider the judges and juries and the amateur and professional advisers involved in legal processes as well as the offenders brought before the courts, with the reasons for prosecuting them and the defences they put forward. The cases examined range from a fourteenth century cause-célèbre, the attempted trial of Pope Boniface VIII for heresy, to investigations of obscure people for sexual and religious offences in the city states of Geneva and Venice. Technical terms have been cut to a minimum to ensure accessibility and appeal to lawyers, social, political and legal historians, undergraduate and postgraduates as well as general readers interested in the development of the trial through time.

A vital history of organizing within and beyond the walls of women’s prisons in the 1970s, illuminating a crucial chapter in today’s abolition feminist struggles. This new edition of an award-winning book features a foreword from acclaimed scholar-activist Sarah Haley and an afterword by Thuma. During the 1970s, grassroots women activists in and outside of prisons forged a radical politics against gender violence and incarceration. Scholar-activist Emily L. Thuma traces the making of this anticarceral feminism at the intersections of struggles for racial and economic justice, imprisoned and institutionalized people’s rights, and gender and sexual liberation. All Our Trials chronicles the organizing, ideas, and influence of those who placed criminalized and marginalized women at the heart of their antiviolence mobilizations. This activism confronted a "tough on crime" political agenda and clashed with the mainstream women’s movement’s strategy of resorting to the criminal legal system as a solution to sexual and domestic violence. Drawing on extensive archival research and first-person narratives, Thuma weaves together the stories of mass defense campaigns, prisoner uprisings, coalition organizing, and radical print cultures that cut through prison walls. In the process, All Our Trials reveals a vibrant culture of opposition to interpersonal and state violence that both transforms our understanding of 1970s social movements and illuminates the history of present struggles for transformative justice.

It's hard to conceive of a topic of more broad and personal interest than the study of the mind. In addition to its traditional investigation by the disciplines of psychology, psychiatry, and neuroscience, the mind has also been a focus of study in the fields of philosophy, economics, anthropology, linguistics, computer science, molecular biology, education, and literature. In all these approaches, there is an almost universal fascination with how the mind works and how it affects our lives and our behavior. Studies of the mind and brain have crossed many exciting thresholds in recent years, and the study of mind now represents a thoroughly cross-disciplinary effort. Researchers from a wide range of disciplines seek answers to such questions as: What is mind? How does it operate? What is consciousness? This encyclopedia brings together scholars from the entire range of mind-related academic disciplines from across the arts and humanities, social sciences, life sciences, and computer science and engineering to explore the multidimensional nature of the human mind.

Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: "... very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.

Pulmonary rehabilitation programmes are now a fundamental part of the clinical management of patients with chronic respiratory diseases. This comprehensive reference book places pulmonary rehabilitation within the wider framework of respiratory disease, and the health burden that this now poses worldwide. Part one of the book examines the evidence

An attractive feature of self-regulation therapies is that, instead of doing something to the patients, they teach them to do something for them selves. Furthermore, the fact that the patient is able to do something to cope with his or her health problem can produce a significant reduction in the stress that may have contributed to that problem and in the additional stress that it produces. While the idea that the mind can playa role in the health of the body and some therapeutic techniques based on this idea are not new, remarkable scientific advances have been made recently in the area of self-regulation and health. There has been an exciting and rapidly accel erating increase in our basic science knowledge of homeostasis, or, in other words, how the body regulates itself in order to maintain health. Technical and conceptual advances are increasing our knowledge of the details of such regulation at all levels-cells, tissues, organs, organ sys tems, and the body as a whole. We are learning how the competing demands of different elements at each of these levels are adjusted by the brain, which, with its neural and humoral mechanisms, is the supreme organ of integration of the body.