Seventy years ago, Erwin Schrödinger posed a profound question: 'What is life, and how did it emerge from non-life?' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged. This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

The central theme, which threads through the entire book, concerns computational modeling methods for water. Modeling results for pure liquid water, water near ions, water at interfaces, water in biological microsystems, and water under other types of perturbations such as laser fields are described. Connections are made throughout the book with statistical mechanical theoretical methods on the one hand and with experimental data on the other. The book is expected to be useful not only for theorists and computer analysts interested in the physical, chemical, biological and geophysical aspects of water, but also for experimentalists in these fields.

This textbook provides an integrated physical and biochemical foundation for undergraduate students majoring in biology or health sciences. It is particularly suitable for students planning to enter the pharmaceutical industry. This new generation of molecular biologists and biochemists will harness the tools and insights of physics and chemistry to exploit the emergence of genomics and systems-level information in biology, and will shape the future of medicine.

Understanding how simple molecules have given rise to the complex biochemical systems and processes of contemporary biology is widely regarded as one of chemistry’s great unsolved questions. There are numerous theories as to the origins of life, the majority of which draw on the idea that DNA and nucleic acids are the central dogma of biology. The Singularity of Nature: A Convergence of Biology, Chemistry and Physics takes a systems-based approach to the origin and evolution of complex life. Readers will gain a novel understanding of physiologic evolution and the limits to our current understanding: why biology remains descriptive and non-predictive, as well as offering new opportunities for understanding relationships between physics and biology in the origins of biological life at the cellular-molecular level.

This volume contains the lectures presented at the second course of the International School of Space Chemistry held in Erice (Sicily) from October 20 - 30 1991 at the "E. Majorana Centre for Scientific Culture". The course was attended by 58 participants from 13 countries. The Chemistry of Life's Origins is well recognized as one of the most critical subjects of modem chemistry. Much progress has been made since the amazingly perceptive contributions by Oparin some 70 years ago when he first outlined a possible series of steps starting from simple molecules to basic building blocks and ultimate assembly into simple organisms capable of replicating, catalysis and evolution to higher organisms. The pioneering experiments of Stanley Miller demonstrated already forty years ago how easy it could have been to form the amino acids which are critical to living organisms. However we have since learned and are still learning a great deal more about the primitive conditions on earth which has led us to a rethinking of where and how the condition for prebiotic chemical processes occurred. We have also learned a great deal more about the molecular basis for life. For instance, the existence of DNA was just discovered forty years ago.

Light and Life in the Universe: Selected Lectures in Physics, Biology and the Origin of Life is a collection of lectures given at the 1964 Nuclear Research Foundation Summer Science School for High School Students, held at the University of Sydney, Australia, on January 6-17, 1964. The papers explore various aspects of life, both on earth and in the universe generally. Emphasis is placed on the ""units"" of living matter, how life may have started on earth, and the possibility of life on other planets. This book is comprised of 15 chapters and begins with a brief description of some of the properties of atoms and how they join up to form molecules, as well as some of the properties of the central core of each atom. The discussion then turns to electromagnetic radiation, highlighting the difficulties originally encountered by Ernest Rutherford's picture of the atom. Subsequent chapters focus on the influence of gravitational fields; the origin of the solar system; the evolution of life on earth; and link between the primordial atmosphere and the origin of life. The functions of proteins, the practical effects of biology on humans, and the replication of living molecules are also considered. This monograph is written specifically for fourth-year high school students interested in astronomy, physics, chemistry, and biology.

In this book, physics in its many aspects (thermodynamics, mechanics, electricity, fluid dynamics) is the guiding light on a fascinating journey through biological systems, providing ideas, examples and stimulating reflections for undergraduate physics, chemistry and life-science students, as well as for anyone interested in the frontiers between physics and biology. Rather than introducing a lot of new information, it encourages young students to use their recently acquired knowledge to start seeing the physics behind the biology. As an undergraduate textbook in introductory biophysics, it includes the necessary background and tools, including exercises and appendices, to form a progressive course. In this case, the chapters can be used in the order proposed, possibly split between two semesters. The book is also an absorbing read for researchers in the life sciences who wish to refresh or go deeper into the physics concepts gleaned in their early years of scientific training. Less physics-oriented readers might want to skip the first chapter, as well as all the "gray boxes" containing the more formal developments, and create their own á-la-carte menu of chapters.

Pross examines these issues from a chemical perspective, providing a new understanding of how the sciences of chemistry and biology relate to one another.

of these subjects and should be kept constantly at hand so that it can readily be consulted when difficult topics arise. I hope that it may succeed in reducing the fear with which many nurses face the sciences with which the book deals. Section 1 BIOLOGY 2 The cell and its requirements The world of living things is conveniently and conven tionally divided into two great groups, the animals and the plants. Broadly speaking the important feature which distinguishes plants is that they can manufacture most of the substances they require by trapping and using various forms of outside energy, in particular the energy of sunlight. In the process of photosynthesis they utilize the energy of light to build up complex chemical substances from relatively simple ones. In contrast, animals lack the ability to use light or any other form of outside energy. Instead they must obtain the energy they require by breaking down complex substances which ultimately they always obtain from plants. Plant-eating animals such as cows and sheep obtain these substances directly. Carnivores obtain them indirectly after they have passed through the bodies of other animals.