Anne Neville was queen to England's most notorious king, Richard III. She was immortalised by Shakespeare for the remarkable nature of her marriage, a union which brought together a sorrowing widow with her husband's murderer. Anne's misfortune did not end there. In addition to killing her first husband, Richard also helped kill her father, father-in-law and brother-in-law, imprisoned her mother, and was suspected of poisoning Anne herself. Dying before the age of thirty, Anne Neville packed into her short life incident enough for many adventurous careers, but was always, apparently, the passive instrument of others' evil intentions. This fascinating new biography seeks to tell the story of Anne's life in her own right, and uncovers the real wife of Richard III by charting the remarkable twists and turns of her fraught and ultimately tragic life.

Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.

Includes articles on issues of worldwide anthropological interest.