This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.

Arguably the most important ancillary test available to ophthalmologists worldwide, optical coherence tomography (OCT) has revolutionized the field, and now includes angiographic evaluations (OCTA) that provide vascular flow data without eye injection. Handbook of Retinal OCT is an easy-to-use, high-yield guide to both OCT and OCTA imaging for practitioners at any stage of their career. Highly templated, concise, and portable, this revised edition helps you master the latest imaging methods used to evaluate retinal disease, uveitis, and optic nerve disorders. - Helps all health professionals with an interest in OCT to better and more quickly interpret OCT imaging, offering quick, highly visual guidance for evaluating age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, and much more. - Provides quick answers with bulleted, templated chapters, each focused on one specific diagnosis or group of diagnoses with a particular OCT appearance. - Demonstrates how the full spectrum of diseases presents through approximately 400 illustrations, including the highest-quality spectral-domain OCT images available and more than 50 new OCTA images. - Includes five new chapters covering optic nerve disease with retinal findings, pachychoroid diseases, paracentral acute middle maculopathy (PAMM), auto-immune retinopathies, and primary uveal lymphoma. - Offers clear visual guidance on image patterns with multiple arrows and labels throughout to highlight key details of each disease.

High-speed anterior segment optical coherence tomography (OCT) offers a non-contact method for high resolution cross-sectional and three-dimensional imaging of the cornea and the anterior segment of the eye. As the first text completely devoted to this topic, Anterior Segment Optical Coherence Tomography comprehensively explains both the scientific principles and the clinical applications of this exciting and advancing technology. Anterior Segment Optical Coherence Tomography enhances surgical planning and postoperative care for a variety of anterior segment applications by expertly explaining how abnormalities in the anterior chamber angle, cornea, iris, and lens can be identified and evaluated using the Visante OCT(TM). Inside Anterior Segment Optical Coherence Tomography, Dr. Roger Steinert and Dr. David Huang, along with 22 of the field's leading professionals, provide a wealth of useful clinical and physiological material about this new diagnostic imaging technique. Valuable images are included to assist in the pre- and postoperative assessment of various anterior segment disorders. Additionally, this unique resource contains detailed information on biometric measurements to enhance diagnostic capability. On the leading edge of anterior segment imaging: - Mapping of corneal thickness and keratoconus evaluation - Measurement of LASIK flap and stromal bed thickness - Visualization and measurement of anterior chamber angle and diagnosis of narrow angle glaucoma - Measuring the dimensions of the anterior chamber and assessing the fit of intraocular lens implants - Visualizing and measuring the results of corneal implants and lamellar procedures - Imaging through corneal opacity to see internal eye structures With the increase in popularity of anterior chamber imaging, and anterior segment OCT proving to be the best tool for high resolution biometry, Anterior Segment Optical Coherence Tomography is a must-have for anterior segment, refractive, cornea, and glaucoma surgeons.

Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.

"The recent introduction of optical coherence tomography angiography (OCTA) has remarkably expanded our knowledge of different retinal, chorioretinal, and optic disc disorders. OCTA is nowadays often introduced as a routine exam in clinical practice, granting the opportunity to non-invasively investigate retinal and choroidal circulation. In this book, many major experts in posterior eye imaging share their experiences and their latest images and ideas about OCTA"--

The second edition of Spectral Domain OCT is a practical guide to the investigation and diagnosis of retinal disease using the Topcon machine. Beginning with an overview of OCT, the book provides a step by step approach to image capture, analysis and interpretation. With the help of numerous case studies, OCT patterns in different types of retinal disease are presented as both 2D and 3D images. In addition, Spectral Domain OCT highlights features of the new Topcon 2000 machine with an enhanced speed of 27,000 A scans/second, improved software algorithms and extra facilities for anterior segment imaging.

Optical Coherence Tomography (OCT) plays a vital role in pediatric retina diagnosis, often revealing unrecognized retinal disorders and connections to brain injury, disease, and delayed neurodevelopment. Handbook of Pediatric Retinal OCT and the Eye-Brain Connection provides authoritative, up-to-date guidance in this promising area, showing how to optimize imaging in young children and infants, how to accurately interpret these images, and how to identify links between these images and brain and developmental disorders. - Illustrates optimal methods of OCT imaging of children and infants, how to avoid pitfalls, and how to recognize and avoid artifacts - Explains how the OCT image may relate to brain disease and delayed neurodevelopment - Features more than 200 high-quality images and scans that depict the full range of disease in infants and young children - Provides guidance in identifying retinal layers and important abnormalities. - Covers the structural features of the retina and optic nerve head in developmental, acquired, or inherited conditions that affect the eye and visual pathways - Offers practical ways to set up imaging programs in the clinic, operating room, or neonatal nursery

The first comprehensive review of the use of optical coherence tomography in neurological diseases for neurologists, neuro-ophthalmologists, and neuroradiologists.

Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT.