This is an open access title available under the terms of a CC BY-NC 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of the detailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a toolbox' by field investigators. It has been compiled by an international group of over 30 authors with direct experience in the design, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience. Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studies to pilot testing.

Many children with mental health problems do not receive support and there are often extensive waiting lists for Children and Young People's Mental Health Services, which are increasingly overstretched. Unfortunately, a large proportion of children with mental health disorders do not accessevidence-based treatment. Low-intensity psychological interventions are now recommended by a number of national guidelines and in the UK, are being implemented by a new workforce of Child Wellbeing Practitioners (CWPs).The Oxford Guide to Brief and Low Intensity Interventions for Children and Young People provides a comprehensive resource for therapists, services and training providers regarding the use, delivery, and implementation of brief and low intensity psychological interventions within a child andadolescent context. It includes concise, focused chapters from leading experts in the field, combining the most up-to-date research with practical considerations regarding the delivery of low intensity interventions.The first of its kind, this book will be an indispensable resource for practitioners, services, and training courses internationally.

This book takes you step-by-step through the Low-intensity CBT interventions and clinical procedures. With an Online Resource site of accompanying workbooks and worksheets, it provides a comprehensive manual for trainee and qualified Psychological Wellbeing Practitioners.

Mental disorders such as depression and anxiety are increasingly common. Yet there are too few specialists to offer help to everyone, and negative attitudes to psychological problems and their treatment discourage people from seeking it. As a result, many people never receive help for these problems. The Oxford Guide to Low Intensity CBT Interventions marks a turning point in the delivery of psychological treatments for people with depression and anxiety. Until recently, the only form of psychological intervention available for patients with depression and anxiety was traditional one-to-one 60 minute session therapy - usually with private practitioners for those patients who could afford it. Now Low Intensity CBT Interventions are starting to revolutionize mental health care by providing cost effective psychological therapies which can reach the vast numbers of people with depression and anxiety who did not previously have access to effective psychological treatment. The Oxford Guide to Low Intensity CBT Interventions is the first book to provide a comprehensive guide to Low Intensity CBT interventions. It brings together researchers and clinicians from around the world who have led the way in developing evidence-based low intensity CBT treatments. It charts the plethora of new ways that evidence-based low intensity CBT can be delivered: for instance, guided self-help, groups, advice clinics, brief GP interventions, internet-based or book-based treatment and prevention programs, with supported provided by phone, email, internet, sms or face-to-face. These new treatments require new forms of service delivery, new ways of communicating, new forms of training and supervision, and the development of new workforces. They involve changing systems and routine practice, and adapting interventions to particular community contexts. The Oxford Guide to Low Intensity CBT Interventions is a state-of-the-art handbook, providing low intensity practitioners, supervisors, managers commissioners of services and politicians with a practical, easy-to-read guide - indispensible reading for those who wish to understand and anticipate future directions in health service provision and to broaden access to cost-effective evidence-based psychological therapies.

Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an individual's circumstances and perceptions. A substantial body of evidence demonstrates that social isolation presents a major risk for premature mortality, comparable to other risk factors such as high blood pressure, smoking, or obesity. As older adults are particularly high-volume and high-frequency users of the health care system, there is an opportunity for health care professionals to identify, prevent, and mitigate the adverse health impacts of social isolation and loneliness in older adults. Social Isolation and Loneliness in Older Adults summarizes the evidence base and explores how social isolation and loneliness affect health and quality of life in adults aged 50 and older, particularly among low income, underserved, and vulnerable populations. This report makes recommendations specifically for clinical settings of health care to identify those who suffer the resultant negative health impacts of social isolation and loneliness and target interventions to improve their social conditions. Social Isolation and Loneliness in Older Adults considers clinical tools and methodologies, better education and training for the health care workforce, and dissemination and implementation that will be important for translating research into practice, especially as the evidence base for effective interventions continues to flourish.

Natalie Rathvon appears as sole author on first (1999) and second (2008) editions' title pages.

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

This Research Topic is a part of the Delft 2021: 1st Sociohydrology Conference series. To view the other sessions please follow the links below: Innovating a New Knowledge Base for Water Justice Studies: Hydrosocial, Sociohydrology, and Beyond Scale Issues in Human-Water Systems Water Resources and Human Behavior: Analysis and Modeling of Coupled Water-Human Systems Feedbacks and Coevolution Innovative Sensing, Observing, Measuring and Analysing Human-Water Data “Pluralistic water research” integrates the hydrological and the social to provide sustainable solutions to water crises. While relying upon robust quantitative modelling, sociohydrology captures crises across many waters (surface, ground and interstitial) along quantity and quality dimensions, hydrosocial unfurls power hierarchies in access to safe and required quota of water, be it for drinking or irrigation purposes. The success of engineering solutions laying out “hard” interventions such as solar powered irrigation, dams, high yielding crop varieties, water treatment plants and water distributions and purifications depend on “soft” socio-political, cultural and psychological variables like the political landscape, community behaviours and governance arrangements. How these soft parameters limit or advance the effect of hard interventions await more enhanced modelling and place-based qualitative analyses to disentangle various cause-effect pathways. While historical and process-based sociohydrology accommodates detailed temporal datasets and causal relationships across human-water systems, the hydrosocial paradigm reconciles “non-modern”, anti-hegemonic, water techniques and knowledge systems, animating local agencies within specific hydroscapes. This issue is dedicated to capture real time innovations through which water challenges have been confronted. It intends to unravel “storylines” along actionable water projects, reflecting on mediations across multiple actors and networks in specific spatio-temporal and cultural contexts, finally drawing our attention to the correlation between projected promises and actual realities. Situated at the crossroads of “boundary work”, we invite articles that will deploy a range of interdisciplinary frameworks like RANAS (Risk, Attitude, Norms, Ability, and Self-regulation), APIE (Awareness, Participation, Involvement and Engagement), HUPE (Historical Urban Political Ecology), etc. to demonstrate coupled sociohydrological and hydrosocial realties and in turn getting informed by empirical insights emanating from these actual water interventions. The final aim of the special issue is not to showcase water just actual interventions but to elicit a rigorous mapping of sustainable processes facilitating collective co-production of resilient water trajectories.