A practical guide to understanding and overcoming addiction to cocaine and meth.

This book focuses on the DNA-binding transcription factors and the proteins with which they directly interact. It examines the regulatory systems that modulate gene expression in all cells and the more specialized systems that regulate localized gene expression throughout the mammalian organism.

The United States Government Internet Directory (formerly the e-Government and Web Directory: U.S. Federal Government Online) serves as a guide to the changing landscape of government information online. The Directory is an indispensable guidebook for anyone who is looking for official U.S. government resources on the Web. The U.S. government's information online is massive and can be difficult to locate. Thus you need The United States Government Internet Directory to navigate the maze of data and locate the materials you seek. --Book Jacket.

Newfoundland lies at the intersection of arctic and more temperate regions and, commensurate with this geography, populations of two Amerindian and two Paleoeskimo cultural traditions occupied Port au Choix, in northern Newfoundland, Canada, for centuries and millennia. Over the past two decades The Port au Choix Archaeology Project has sought a comparative understanding of how these different cultures, each with their particular origin and historical trajectory, adapted to the changing physical and social environments, impacted their physical surroundings, and created cultural landscapes. This volume brings together the research of Renouf, her colleagues and her students who together employ multiple perspectives and methods to provide a detailed reconstruction and understanding of the long-term history of Port au Choix. Although geographically focussed on a northern coastal area, this volume has wider implications for understanding archaeological landscapes, human-environment interactions and hunter-gatherer societies.

Blending theory with practical application, this comprehensive text supports courses at the intersection of corporate social responsibility (CSR), corporate strategy, and public policy. Part I provides an overview of the field, defining CSR and placing it in the context of wider corporate strategy. Part II contains chapters on CSR issues related to the organization, the economy, and society, and provides detailed case studies on a variety of well-known firms. Adopting a stakeholder perspective, the authors explore CSR issues within the complex global business environment in which corporations operate today.

Updated to reflect the latest discoveries in the field, the Fifth Edition of Hartl's classic text provides an accessible, student-friendly introduction to contemporary genetics. Designed for the shorter, less comprehensive introductory course, Essential Genetics: A Genomic Perspective, Fifth Edition includes carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. New and updated sections on genetic analysis, molecular genetics, probability in genetics, and pathogenicity islands ensure that students are kept up-to-date on current key topics. The text also provides students with a sense of the social and historical context in which genetics has developed. The updated companion web site provides numerous study tools, such as animated flashcards, crosswords, practice quizzes and more! New and expanded end-of-chapter material allows for a mastery of key genetics concepts and is ideal for homework assignments and in-class discussion.

From Kanorado to Pawnee villages, Kansas is a land rich in archaeological sites--nearly 12,000 known-that testify to its prehistoric heritage. This volume presents the first comprehensive overview of Kansas archaeology in nearly fifty years, containing the most current descriptions and interpretations of the state's archaeological record. Building on Waldo Wedel's classic Introduction to Kansas Archaeology, it synthesizes more than four decades of research and discusses all major prehistoric time periods in one readily accessible resource. In Kansas Archaeology, a team of distinguished contributors, all experts in their fields, synthesize what is known about the human presence in Kansas from the age of the mammoth hunters, circa 10,000 B.C., to Euro-American contact in the mid-nineteenth century. Covering such sites as Kanorado-one of the oldest in the Americas-the authors review prehistoric peoples of the Paleoarchaic era, Woodland cultures, Central Plains tradition, High Plains Upper Republican culture, Late Prehistoric Oneota, and Great Bend peoples. They also present material on three historic cultures: Wichita, Kansa, and Pawnee. The findings presented here shed new light on issues such as how people adapted to environmental shifts and the impact of technological innovation on social behavior. Included also are chapters on specialized topics such as plant use in prehistory, sources of stone for tool manufacture, and the effects of landscape evolution on sites. Chapters on Kansas culture history also reach into the surrounding region and offer directions for future inquiry. More than eighty illustrations depict a wide range of artifacts and material remains. An invaluable resource for archaeologists and students, Kansas Archaeology is also accessible to interested laypeople--anyone needing a summary of the material remains that have been found in Kansas. It demonstrates the major advances in our understanding of Kansas prehistory that have applications far beyond its borders and point the way toward our future understanding of the past.

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